Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Joel McMillan"'
Autor:
Adrien Eberlin, Jörn Dengjel, Anne Von Maessenhausen, Michael Schleicher, Philipp Metzger, Roland Schüle, Manfred Jung, Stefan Gerhardt, Joel McMillan, Ralf Flaig, Oliver Einsle, Dominica Willmann, Ignasi Forné, Daniel Wohlwend, Eric Metzger, Axel Imhof, Mark T. Bedford, Anne Kathrin Schott, Kerstin Petroll, Sven Perner, Alexsandra B. Espejo, Katrin M. Schüle, Sylvia Urban
Publikováno v:
Nature Structural & Molecular Biology. 23:132-139
Prostate cancer evolution is driven by a combination of epigenetic and genetic alterations such as coordinated chromosomal rearrangements, termed chromoplexy. TMPRSS2-ERG gene fusions found in human prostate tumors are a hallmark of chromoplexy. TMPR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3894e756650aedbaaafe92bb9999904
https://doi.org/10.1038/nsmb.3153
https://doi.org/10.1038/nsmb.3153
Autor:
Joel McMillan, Dina Robaa, Luca Carlino, Chiara Luise, Ralf Flaig, Tobias Wagner, Manfred Jung, Wolfgang Sippl, Roland Schüle
Publikováno v:
ChemMedChem. 11(20)
The methyllysine reader protein Spindlin1 has been implicated in the tumorigenesis of several types of cancer and may be an attractive novel therapeutic target. Small-molecule inhibitors of Spindlin1 should be valuable as chemical probes as well as p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda5f8e43b7663eb780f07400bbc8b9d
https://pubmed.ncbi.nlm.nih.gov/27634332
https://pubmed.ncbi.nlm.nih.gov/27634332