Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Joel McIntosh"'
Autor:
Joel McIntosh
Publikováno v:
20 Ideas for Teaching Gifted Kids in the Middle School and High School ISBN: 9781003419358
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3dc63707ca809d6aa65e6057e453bd2
https://doi.org/10.4324/9781003419358-4
https://doi.org/10.4324/9781003419358-4
Autor:
Joel McIntosh
Publikováno v:
20 Ideas for Teaching Gifted Kids in the Middle School and High School ISBN: 9781003419358
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4265738437cfb7f1e149cec3c65cd78
https://doi.org/10.4324/9781003419358-2
https://doi.org/10.4324/9781003419358-2
Autor:
Joel McIntosh
Publikováno v:
20 Ideas for Teaching Gifted Kids in the Middle School and High School ISBN: 9781003419358
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea4ce45b866664da818eddfe86582ada
https://doi.org/10.4324/9781003419358-1
https://doi.org/10.4324/9781003419358-1
Autor:
Joel McIntosh
Publikováno v:
20 Ideas for Teaching Gifted Kids in the Middle School and High School ISBN: 9781003419358
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fd723724fdd63de1931eb7f3b7e3da6
https://doi.org/10.4324/9781003419358-5
https://doi.org/10.4324/9781003419358-5
Autor:
Joel McIntosh
Publikováno v:
20 Ideas for Teaching Gifted Kids in the Middle School and High School ISBN: 9781003419358
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96e5a2b9940f51615bc4efc05535ea7d
https://doi.org/10.4324/9781003419358-3
https://doi.org/10.4324/9781003419358-3
Autor:
Deyi Zhang, Hailey M. Harris, Jonathan Chen, Jen Judy, Gabriella James, Aileen Kelly, Joel McIntosh, Austin Tenn-McClellan, Eileen Ambing, Ying Siow Tan, Hao Lu, Stefan Gajewski, Matthew C. Clifton, Stephanie Yung, Daniel W. Robbins, Mehdi Pirooznia, Sigrid S. Skånland, Erika Gaglione, Maissa Mhibik, Chingiz Underbayev, Inhye E. Ahn, Clare Sun, Sarah E. M. Herman, Mark Noviski, Adrian Wiestner
Publikováno v:
Blood.
Bruton tyrosine kinase (BTK) is essential for B-cell receptor (BCR) signaling, a driver of chronic lymphocytic leukemia (CLL). Covalent inhibitors bind C481 in the active site of BTK and have become a preferred CLL therapy. Disease progression on cov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498c126a31ed92c458ccf4c6fb1cb394
https://pubmed.ncbi.nlm.nih.gov/36375120
https://pubmed.ncbi.nlm.nih.gov/36375120
Autor:
Jeffrey T. Mihalic, Nivetha Brathaban, Brandon Bravo, Timothy Ingallinera, Daisuke Kato, Hao Lu, Jun Ma, Joel McIntosh, Austin Tenn-McClellan, Ratul Mukerji, Mark A. Noviski, Ge Peng, Luz Perez, Ryan Rountree, May Tan, Jeffrey Wu, Jordan Ye, Stephanie Yung
Publikováno v:
Cancer Research. 83:3423-3423
Chronic activation of Bruton’s Tyrosine Kinase (BTK) signaling is a hallmark of B cell malignancies. Over the last decade, covalent and reversible inhibitors of BTK have proven effective for the treatment of many of these including chronic lymphocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87566cd02d9779e22cd5117c50be20da
https://doi.org/10.1158/1538-7445.am2023-3423
https://doi.org/10.1158/1538-7445.am2023-3423
Autor:
Aparna Sundaram, Dean Sheppard, Sean Liu, You-Zhi Tang, Nilgun Isik Reed, Seul Ki Yeon, Hyunjun Yang, Chun Chen, Richard T. Beresis, Joel McIntosh, Marc Adler, Ian B. Seiple, Hyunil Jo, William F. DeGrado
Publikováno v:
Bioorg Med Chem Lett
Inhibition of integrin alpha5beta1 emerges as a novel therapeutic option to block transmission of contractile forces during asthma attack. We designed and synthesized novel inhibitors of integrin alpha5beta1 by backbone replacement of known alphavbet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11c914bfea385636c854bba196faeca
https://doi.org/10.1016/j.bmcl.2020.127578
https://doi.org/10.1016/j.bmcl.2020.127578
Autor:
Annafelicia Civitavecchia, You-Zhi Tang, Yibing Wu, Dean Sheppard, Hyunil Jo, Joel McIntosh, Nilgun Isik Reed, Kathleen S. Molnar, William F. DeGrado
Publikováno v:
ACS medicinal chemistry letters, vol 7, iss 10
One small molecule inhibitor of αvβ1 integrin, c8, shows antifibrotic effects in multiple in vivo mouse models. Here we synthesized c8 analogues and systematically investigate their structure-activity relationships (SAR) in αvβ1 integrin inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c874697ed5eebef0db8c418ad100353
https://europepmc.org/articles/PMC5066160/
https://europepmc.org/articles/PMC5066160/
Autor:
David M, Goldstein, Michael, Soth, Tobias, Gabriel, Nolan, Dewdney, Andreas, Kuglstatter, Humberto, Arzeno, Jeffrey, Chen, William, Bingenheimer, Stacie A, Dalrymple, James, Dunn, Robert, Farrell, Sandra, Frauchiger, JoAnn, La Fargue, Manjiri, Ghate, Bradford, Graves, Ronald J, Hill, Fujun, Li, Renee, Litman, Brad, Loe, Joel, McIntosh, Daniel, McWeeney, Eva, Papp, Jaehyeon, Park, Harlan F, Reese, Richard T, Roberts, David, Rotstein, Bong, San Pablo, Keshab, Sarma, Martin, Stahl, Man-Ling, Sung, Rebecca T, Suttman, Eric B, Sjogren, Yunchou, Tan, Alejandra, Trejo, Mary, Welch, Paul, Weller, Brian R, Wong, Hasim, Zecic
Publikováno v:
Journal of medicinal chemistry. 54(7)
The development of a new series of p38α inhibitors resulted in the identification of two clinical candidates, one of which was advanced into a phase 2 clinical study for rheumatoid arthritis. The original lead, an lck inhibitor that also potently in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cda31600d6054cc75ed83ea768d5f392
https://pubmed.ncbi.nlm.nih.gov/21375264
https://pubmed.ncbi.nlm.nih.gov/21375264