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pro vyhledávání: '"Joel M. Schrock"'
Autor:
Travis C. Palmer, Joel M. Schrock, Rashad R. Karimov, Susruta Majumdar, Julie E. Pickett, Steven G. Grinnell, András Váradi, Gavril W. Pasternak
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1761-1764
Trialkylstannanes are versatile precursors for chemical transformations, including radiolabeling with a variety of halogens, particularly iodine. In the present work a convenient, Pd-mediated stannylation method is presented that can be performed in
Autor:
Joel M. Schrock, Gavril W. Pasternak, Christina M. Spino, Stacy M. Stabler, Charles G. Longen, Felix J. Kim, Jacqueline C. Marino
Publikováno v:
Molecular pharmacology. 84(5)
The Sigma1 receptor (Sigma1) is an endoplasmic reticulum (ER) integral membrane protein that is highly expressed in a number of cancer cell lines. Small molecule compounds targeting Sigma1 (Sigma1 ligands) inhibit cancer cell proliferation and induce
Autor:
Joel M. Schrock, Gavril W. Pasternak, Felix J. Kim, Mohammad Mainul Islam, Steven G. Grinnell
Publikováno v:
The FASEB Journal. 27
Publikováno v:
Biochemical and biophysical research communications. 426(2)
Treatment with sigma1 receptor (Sigma1) ligands can inhibit cell proliferation in vitro and tumor growth in vivo. However, the cellular pathways engaged in response to Sigma1 ligand treatment that contribute to these outcomes remain largely undefined
Publikováno v:
The FASEB Journal. 24