Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Joel Lanoix"'
Autor:
Jean-David Larouche, Céline M Laumont, Assya Trofimov, Krystel Vincent, Leslie Hesnard, Sylvie Brochu, Caroline Côté, Juliette F Humeau, Éric Bonneil, Joel Lanoix, Chantal Durette, Patrick Gendron, Jean-Philippe Laverdure, Ellen R Richie, Sébastien Lemieux, Pierre Thibault, Claude Perreault
Publikováno v:
eLife, Vol 12 (2024)
Transposable elements (TEs) are repetitive sequences representing ~45% of the human and mouse genomes and are highly expressed by medullary thymic epithelial cells (mTECs). In this study, we investigated the role of TEs on T-cell development in the t
Externí odkaz:
https://doaj.org/article/f8e5dc8f11474cf292db53bbc1880f9d
Autor:
Nada Jabado, Claudia L. Kleinman, Livia Garzia, Michael D. Taylor, Stephen C. Mack, Benjamin A. Garcia, Peter W. Lewis, Pierre Thibault, Jay S. Wunder, Robert Turcotte, Brendan C. Dickson, Jason Karamchandani, Sungmi Jung, Ashot S. Harutyunyan, Véronique Lisi, Robert Eveleigh, Tianna S. Sihota, Kateryna Rossokhata, Siddhant U. Jain, Takeaki Ishii, Éric Bonneil, Joel Lanoix, Dylan M. Marchione, Damien Faury, Leonie G. Mikael, Carol C.L. Chen, Wajih Jawhar, Liam D. Hendrikse, Shriya Deshmukh, Nicolas De Jay, Sima Khazaei
Differential Expression in Isogenic Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1343050be4db44fce4eca262d777317
https://doi.org/10.1158/2159-8290.22535012
https://doi.org/10.1158/2159-8290.22535012
Autor:
Nada Jabado, Claudia L. Kleinman, Livia Garzia, Michael D. Taylor, Stephen C. Mack, Benjamin A. Garcia, Peter W. Lewis, Pierre Thibault, Jay S. Wunder, Robert Turcotte, Brendan C. Dickson, Jason Karamchandani, Sungmi Jung, Ashot S. Harutyunyan, Véronique Lisi, Robert Eveleigh, Tianna S. Sihota, Kateryna Rossokhata, Siddhant U. Jain, Takeaki Ishii, Éric Bonneil, Joel Lanoix, Dylan M. Marchione, Damien Faury, Leonie G. Mikael, Carol C.L. Chen, Wajih Jawhar, Liam D. Hendrikse, Shriya Deshmukh, Nicolas De Jay, Sima Khazaei
Glycine 34-to-tryptophan (G34W) substitutions in H3.3 arise in approximately 90% of giant cell tumor of bone (GCT). Here, we show H3.3 G34W is necessary for tumor formation. By profiling the epigenome, transcriptome, and secreted proteome of patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::240c3963b5983b5d16a4ad808d771db7
https://doi.org/10.1158/2159-8290.c.6547733.v1
https://doi.org/10.1158/2159-8290.c.6547733.v1
Autor:
Nada Jabado, Claudia L. Kleinman, Livia Garzia, Michael D. Taylor, Stephen C. Mack, Benjamin A. Garcia, Peter W. Lewis, Pierre Thibault, Jay S. Wunder, Robert Turcotte, Brendan C. Dickson, Jason Karamchandani, Sungmi Jung, Ashot S. Harutyunyan, Véronique Lisi, Robert Eveleigh, Tianna S. Sihota, Kateryna Rossokhata, Siddhant U. Jain, Takeaki Ishii, Éric Bonneil, Joel Lanoix, Dylan M. Marchione, Damien Faury, Leonie G. Mikael, Carol C.L. Chen, Wajih Jawhar, Liam D. Hendrikse, Shriya Deshmukh, Nicolas De Jay, Sima Khazaei
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a59f6967731efe8b32605d91a9136f7
https://doi.org/10.1158/2159-8290.22535021
https://doi.org/10.1158/2159-8290.22535021
Autor:
Nada Jabado, Claudia L. Kleinman, Livia Garzia, Michael D. Taylor, Stephen C. Mack, Benjamin A. Garcia, Peter W. Lewis, Pierre Thibault, Jay S. Wunder, Robert Turcotte, Brendan C. Dickson, Jason Karamchandani, Sungmi Jung, Ashot S. Harutyunyan, Véronique Lisi, Robert Eveleigh, Tianna S. Sihota, Kateryna Rossokhata, Siddhant U. Jain, Takeaki Ishii, Éric Bonneil, Joel Lanoix, Dylan M. Marchione, Damien Faury, Leonie G. Mikael, Carol C.L. Chen, Wajih Jawhar, Liam D. Hendrikse, Shriya Deshmukh, Nicolas De Jay, Sima Khazaei
Supplementary Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3990edb0e171ee5bbb7e67ab02fa67cb
https://doi.org/10.1158/2159-8290.22535027.v1
https://doi.org/10.1158/2159-8290.22535027.v1
Autor:
Caroline Côté, Chantal Durette, Jean-Philippe Laverdure, Claude Perreault, Pamela S. Ohashi, Mathieu Courcelles, Qingchuan Zhao, Patrick Gendron, Céline M. Laumont, Eric Bonneil, Joel Lanoix, Krystel Vincent, Sébastien Lemieux, Douglas G. Millar, Pierre Thibault
Publikováno v:
Cancer Immunology Research. 8:544-555
High-grade serous ovarian cancer (HGSC), the principal cause of death from gynecologic malignancies in the world, has not significantly benefited from advances in cancer immunotherapy. Although HGSC infiltration by lymphocytes correlates with superio
Autor:
Eric Bonneil, Qing Ma, Lukas Reiter, Isabelle Sirois, Joel Lanoix, Etienne Caron, Roland Bruderer, Pierre Thibault, Laura Wessling, David Hamelin, Pouya Faridi, Jerome Despault, Frederic Saab, Eustache Paramithiotis, Chen Li, Mathieu Courcelles, Anthony W. Purcell, Anne Jang, Peter Kubiniok, Kevin A. Kovalchik, Marco Tognetti
Publikováno v:
Molecular & Cellular Proteomics : MCP
MS-based immunopeptidomics is maturing into an automatized and high-throughput technology, producing small- to large-scale datasets of clinically relevant major histocompatibility complex (MHC) class I-associated and class II-associated peptides. Con
Autor:
Leslie Hesnard, Catherine Thériault, Maxime Cahuzac, Chantal Durette, Krystel Vincent, Marie-Pierre Hardy, Joël Lanoix, Gabriel Ouellet Lavallée, Juliette Humeau, Pierre Thibault, Claude Perreault
Publikováno v:
Current Oncology, Vol 31, Iss 6, Pp 3099-3121 (2024)
Epithelial ovarian cancer (EOC) has not significantly benefited from advances in immunotherapy, mainly because of the lack of well-defined actionable antigen targets. Using proteogenomic analyses of primary EOC tumors, we previously identified 91 abe
Externí odkaz:
https://doaj.org/article/12eb4b94c81d4840bf379764f030a99c
Autor:
Caroline Côté, Eric Bonneil, Chantal Durette, Louis M. Staudt, Joel Lanoix, Pierre Thibault, Jaroslav Hollý, Mathieu Courcelles, Marie-Pierre Hardy, Claude Perreault, Sébastien Lemieux, Maria Virginia Ruiz Cuevas, Jonathan W. Yewdell
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108815-(2021)
Cell Rep
Cell Rep
Summary: Combining RNA sequencing, ribosome profiling, and mass spectrometry, we elucidate the contribution of non-canonical translation to the proteome and major histocompatibility complex (MHC) class I immunopeptidome. Remarkably, of 14,498 protein
Autor:
Jenna Cleyle, Marie-Pierre Hardy, Robin Minati, Mathieu Courcelles, Chantal Durette, Joel Lanoix, Jean-Philippe Laverdure, Krystel Vincent, Claude Perreault, Pierre Thibault
Publikováno v:
Molecular & Cellular Proteomics. 21:100228
Colorectal cancer is the second leading cause of cancer death worldwide, and the incidence of this disease is expected to increase as global socioeconomic changes occur. Immune checkpoint inhibition therapy is effective in treating a minority of colo