Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Joel Lachuer"'
Autor:
Hwayoung Noh, Amélie Anota, Rodolf Mongondry, Renaud Meyrand, Carmen Dupuis, Camille Schiffler, Philippe Marijnen, Sabina Rinaldi, Joel Lachuer, Pekka Keski-Rahkonen, Marc J Gunter, Aude Fléchon, Béatrice Fervers, Olivia Pérol
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Testicular germ cell tumours (TGCTs) are the most common malignancy in men aged 15–40 years, with increasing incidence worldwide. About 33 ~ 50% of the patients present with metastatic disease at diagnosis. TGCT survivors experi
Externí odkaz:
https://doaj.org/article/fa667221073545d7a7c16b4f0698925a
Autor:
Sally Badawi, Alexandre Paccalet, Zeina Harhous, Bruno Pillot, Lionel Augeul, Fabien Van Coppenolle, Joel Lachuer, Mazen Kurdi, Claire Crola Da Silva, Michel Ovize, Gabriel Bidaux
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
BackgroundIschemic heart diseases are a major cause of death worldwide. Different animal models, including cardiac surgery, have been developed over time. Unfortunately, the surgery models have been reported to trigger an important inflammatory respo
Externí odkaz:
https://doaj.org/article/6c3122af90444feb9a8395bf73704b54
Autor:
Maroulio Pertesi, Perrine Galia, Nicolas Nazaret, Maxime Vallée, Laurent Garderet, Xavier Leleu, Hervé Avet-Loiseau, Matthieu Foll, Graham Byrnes, Joel Lachuer, James D McKay, Charles Dumontet
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136505 (2015)
The MYD88 L265P is a recurrent somatic mutation in neoplastic cells from patients with Waldenström Macroglobulinemia (WM). We identified the MYD88 L265P mutation in three individuals from unrelated families, but its presence did not explain the dise
Externí odkaz:
https://doaj.org/article/8fd3e8b4e8874f9c931d9d4d3cee592e
Autor:
Benjamin Villalard, Arjan Boltjes, Florie Reynaud, Olivier Imbaud, Karine Thoinet, Ilse Timmerman, Séverine Croze, Emy Theoulle, Gianluigi Atzeni, Joël Lachuer, Jan J. Molenaar, Godelieve A. M. Tytgat, Céline Delloye-Bourgeois, Valérie Castellani
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Despite their indisputable importance in neuroblastoma (NB) pathology, knowledge of the bases of NB plasticity and heterogeneity remains incomplete. They may be rooted in developmental trajectories of their lineage of origin, the sympatho-ad
Externí odkaz:
https://doaj.org/article/8eeee38574194e8a84bc12301a8a48bf
Autor:
Anne-Laure Hemonnot-Girard, Cédric Meersseman, Manuela Pastore, Valentin Garcia, Nathalie Linck, Catherine Rey, Amine Chebbi, Freddy Jeanneteau, Stephen D. Ginsberg, Joël Lachuer, Christelle Reynes, François Rassendren, Hélène Hirbec
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-26 (2022)
Abstract Background Research in recent years firmly established that microglial cells play an important role in the pathogenesis of Alzheimer's disease (AD). In parallel, a series of studies showed that, under both homeostatic and pathological condit
Externí odkaz:
https://doaj.org/article/9574a05f72834460ae566069892f4b65
Autor:
Magali, Roche, Anne, Wierinckx, Séverine, Croze, Catherine, Rey, Catherine, Legras-Lachuer, Anne-Pierre, Morel, Alfredo, Fusco, Gérald, Raverot, Jacqueline, Trouillas, Joel, Lachuer
Publikováno v:
Frontiers in Medicine
Changes in microRNAs (miRNAs) expression in many types of cancer suggest that they may be involved in crucial steps during tumor progression. Indeed, miRNAs deregulation has been described in pituitary tumorigenesis, but few studies have described th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::891063d563cdefffce2042ff730e23bb
https://pubmed.ncbi.nlm.nih.gov/26322309
https://pubmed.ncbi.nlm.nih.gov/26322309
Autor:
Young-Ho, Kim, Joel, Lachuer, Michel, Mittelbronn, Werner, Paulus, Benjamin, Brokinkel, Kathy, Keyvani, Ulrich, Sure, Karsten, Wrede, Sumihito, Nobusawa, Yoichi, Nakazato, Yuko, Tanaka, Anne, Vital, Luigi, Mariani, Hiroko, Ohgaki
Publikováno v:
Brain Pathol
We recently reported that the vast majority (90%) of low-grade diffuse gliomas (diffuse astrocytoma, oligoastrocytoma and oligodendroglioma) carry at least one of the following genetic alterations: IDH1/2 mutation, TP53 mutation or 1p/19q loss. Only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ff7beea9c44886cdcccd3ca809d3b70
https://pubmed.ncbi.nlm.nih.gov/21470325
https://pubmed.ncbi.nlm.nih.gov/21470325
Autor:
Antoine Toubert, Salome Glauzy, Isabelle André-Schmutz, Joel Lachuer, Regis Peffault de Latour, Sophie Servais, Gerard Socié, Emmanuel Clave
Publikováno v:
The Journal of Immunology. 194:140.12-140.12
T-cell reconstitution is delayed by acute Graft-Versus-Host Disease (aGVHD) during allogeneic hematopoietic stem cell transplantation (allo-HSCT). Here, we analyzed transcriptional programs of cell-sorted circulating lymphoid progenitors and CD34+Lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b463fadd23c1e06a4a6750bf1bc8350b
https://doi.org/10.4049/jimmunol.194.supp.140.12
https://doi.org/10.4049/jimmunol.194.supp.140.12
Autor:
Antoine Toubert, Zena Khaznadar, Nicolas Boissel, Sophie Agaugue, Guylaine Henry, Meyling Cheok, Marguerite Vignon, Daniela Geromin, Jean Michel Cayuela, Joel Lachuer, Claude Preudhomme, Herve Dombret, Nicolas Dulphy
Publikováno v:
The Journal of Immunology. 194:211.28-211.28
Acute myeloid leukemia (AML) is a heterogeneous group of malignancies sensitive to natural killer (NK) cell anti-tumor responses. However, NK cells are frequently defective in AML. Here, we found in an exploratory cohort (n = 46) that a different exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22ae9140bcf71e9a51834443a70f9722
https://doi.org/10.4049/jimmunol.194.supp.211.28
https://doi.org/10.4049/jimmunol.194.supp.211.28
Autor:
Aurélie Bellanger, Diep T. Le, Julie Vendrell, Anne Wierinckx, Lőrinc S. Pongor, Jérôme Solassol, Joël Lachuer, Philippe Clezardin, Balázs Győrffy, Pascale A. Cohen
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Oncogene alternative splicing events can create distinct functional transcripts that offer new candidate prognostic biomarkers for breast cancer. ZNF217 is a well-established oncogene but its exon 4-skipping isoform (ZNF217-ΔE4) has never been inves
Externí odkaz:
https://doaj.org/article/447ddc6507a346b49865519fc7d3eb12