Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Joel Kumlin"'
Autor:
Brooke L. McNeil, Simona A. Mastroianni, Scott W. McNeil, Stefan Zeisler, Joel Kumlin, Sogol Borjian, Anthony W. McDonagh, Michael Cross, Paul Schaffer, Caterina F. Ramogida
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract TRIUMF is one of the only laboratories in the world able to produce both lead-203 (203Pb, t1/2 = 51.9 h) and 212Pb (t1/2 = 10.6 h) onsite via its 13 and 500 MeV cyclotrons, respectively. Together, 203Pb and 212Pb form an element-equivalent t
Externí odkaz:
https://doaj.org/article/00133871f67b43aeb202a5568bef9977
Autor:
Helge Thisgaard, Joel Kumlin, Niels Langkjær, Jansen Chua, Brian Hook, Mikael Jensen, Amir Kassaian, Stefan Zeisler, Sogol Borjian, Michael Cross, Paul Schaffer, Johan Hygum Dam
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract Background With increasing clinical demand for gallium-68, commercial germanium-68/gallium-68 ([68Ge]Ge/[68Ga]Ga) generators are incapable of supplying sufficient amounts of the short-lived daughter isotope. In this study, we demonstrate a h
Externí odkaz:
https://doaj.org/article/c1bad25b041946958628af4df04af56c
Autor:
Hua Yang, Feng Gao, Brooke McNeil, Chengcheng Zhang, Zheliang Yuan, Stefan Zeisler, Joel Kumlin, Jutta Zeisler, François Bénard, Caterina Ramogida, Paul Schaffer
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-16 (2021)
Abstract Background 64Cu is one of the few radioisotopes that can be used for both imaging and therapy, enabling theranostics with identical chemical composition. Development of stable chelators is essential to harness the potential of this isotope,
Externí odkaz:
https://doaj.org/article/02d74d0079c0477dac9ddd9c7a511878
Publikováno v:
Instruments, Vol 3, Iss 1, p 16 (2019)
A new solid target system for the TRIUMF TR13 cyclotron that can accommodate target discs with a 1-2-mm thickness and a 28-mm diameter has been developed. The target system design is based on a modified clamping mechanism of a KF-40 vacuum connector,
Externí odkaz:
https://doaj.org/article/2a1c3e7c1cd14be38a5316ff810c88b4
Publikováno v:
Instruments, Vol 3, Iss 1, p 10 (2019)
Gallium-68 is a popular radioisotope for positron emission tomography. To make gallium-68 more accessible, we developed a new solid target for medical cyclotrons. Fused zinc targets promise a new, efficient, and reliable technique without the downsid
Externí odkaz:
https://doaj.org/article/202824f0a5794e4a9acd96d1b90f470f
Autor:
Jutta Zeisler, Feng Gao, Hua Yang, Joel Kumlin, Caterina F. Ramogida, Zheliang Yuan, Chengcheng Zhang, Brooke McNeil, Paul Schaffer, Stefan K. Zeisler, Francois Benard
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-16 (2021)
Background 64Cu is one of the few radioisotopes that can be used for both imaging and therapy, enabling theranostics with identical chemical composition. Development of stable chelators is essential to harness the potential of this isotope, challenge
Autor:
Mathieu L. Lepage, Áron Roxin, Hsiou-Ting Kuo, David M. Perrin, Rajaguru L Kandasamy, Kuo-Shyan Lin, Sungjoon Huh, Alan Limoges, Joel Kumlin, Francois Benard, Stefan K. Zeisler, Zhengxing Zhang, Helen Merkens
Publikováno v:
ChemBioChem. 21:943-947
We report a single-molecule radiotracer that can be labeled independently with 18 F-fluoride or radiometals (64 Cu, 177 Lu) in a single step. A prostate-specific membrane antigen (PSMA)-targeting ligand, armed with both an organotrifluoroborate and a
Autor:
Niels Langkjær, Helge Thisgaard, Johan Hygum Dam, Mikael Jensen, Michael Cross, Brian Hook, Paul Schaffer, Amir Kassaian, Sogol Borjian, Stefan K. Zeisler, Jansen Chua, Joel Kumlin
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-11 (2021)
Thisgaard, H, Kumlin, J, Langkjær, N, Chua, J, Hook, B, Jensen, M, Kassaian, A, Zeisler, S, Borjian, S, Cross, M, Schaffer, P & Dam, J H 2021, ' Multi-curie production of gallium-68 on a biomedical cyclotron and automated radiolabelling of PSMA-11 and DOTATATE ', EJNMMI radiopharmacy and chemistry, vol. 6, 1 . https://doi.org/10.1186/s41181-020-00114-9
EJNMMI Radiopharmacy and Chemistry
Thisgaard, H, Kumlin, J, Langkjær, N, Chua, J, Hook, B, Jensen, M, Kassaian, A, Zeisler, S, Borjian, S, Cross, M, Schaffer, P & Dam, J H 2021, ' Multi-curie production of gallium-68 on a biomedical cyclotron and automated radiolabelling of PSMA-11 and DOTATATE ', EJNMMI radiopharmacy and chemistry, vol. 6, 1 . https://doi.org/10.1186/s41181-020-00114-9
EJNMMI Radiopharmacy and Chemistry
Background With increasing clinical demand for gallium-68, commercial germanium-68/gallium-68 ([68Ge]Ge/[68Ga]Ga) generators are incapable of supplying sufficient amounts of the short-lived daughter isotope. In this study, we demonstrate a high-yield
Autor:
Hua, Yang, Feng, Gao, Brooke, McNeil, Chengcheng, Zhang, Zheliang, Yuan, Stefan, Zeisler, Joel, Kumlin, Jutta, Zeisler, François, Bénard, Caterina, Ramogida, Paul, Schaffer
Publikováno v:
EJNMMI Radiopharmacy and Chemistry
Background 64Cu is one of the few radioisotopes that can be used for both imaging and therapy, enabling theranostics with identical chemical composition. Development of stable chelators is essential to harness the potential of this isotope, challenge
Autor:
Stefan K. Zeisler, Eszter Boros, Brian O. Patrick, Chris Orvig, Paul Schaffer, Michael J. Adam, Caterina F. Ramogida, Joel Kumlin
Publikováno v:
Dalton Transactions. 45:13082-13090
The chiral acyclic "pa" ligand (pa = picolinic acid) H2CHXdedpa (N4O2) and two NI-containing dedpa analogues (H2CHXdedpa-N,N'-propyl-2-NI, H2dedpa-N,N'-propyl-2-NI, NI = nitroimidazole) were studied as chelators for copper radiopharmaceuticals (CHX =