Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Joel I. Pritchard"'
Autor:
James M. Olson, Andrew R. Hallahan, Charles G. Eberhart, Donghoon Lee, Sue E. Knoblaugh, Stacey Hansen, Barbara Pullar, Sally Ditzler, Joel I. Pritchard, Karen D. Tsuchiya, Elisabeth H. Villavicencio, Beryl A. Hatton
Supplementary Figure 3 from The Smo/Smo Model: Hedgehog-Induced Medulloblastoma with 90% Incidence and Leptomeningeal Spread
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097e29c56513b079aa406189fd686122
https://doi.org/10.1158/0008-5472.22373816
https://doi.org/10.1158/0008-5472.22373816
Autor:
James M. Olson, Phillip A. Beachy, Irwin D. Bernstein, Richard G. Ellenbogen, Thomas L. Russell, Beryl A. Hatton, Jennifer Stoeck, Mark Benson, Stacey Hansen, Joel I. Pritchard, Andrew R. Hallahan
3 Tables & 2 Figures from The SmoA1 Mouse Model Reveals That Notch Signaling Is Critical for the Growth and Survival of Sonic Hedgehog-Induced Medulloblastomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4afb6326df8e499ad8616927be272d3c
https://doi.org/10.1158/0008-5472.22363295.v1
https://doi.org/10.1158/0008-5472.22363295.v1
Autor:
James M. Olson, Andrew R. Hallahan, Charles G. Eberhart, Donghoon Lee, Sue E. Knoblaugh, Stacey Hansen, Barbara Pullar, Sally Ditzler, Joel I. Pritchard, Karen D. Tsuchiya, Elisabeth H. Villavicencio, Beryl A. Hatton
Supplementary Figure 2 from The Smo/Smo Model: Hedgehog-Induced Medulloblastoma with 90% Incidence and Leptomeningeal Spread
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1edb1a2291d0559f329cb549bb7e85b
https://doi.org/10.1158/0008-5472.22373819.v1
https://doi.org/10.1158/0008-5472.22373819.v1
Autor:
James M. Olson, Andrew R. Hallahan, Charles G. Eberhart, Donghoon Lee, Sue E. Knoblaugh, Stacey Hansen, Barbara Pullar, Sally Ditzler, Joel I. Pritchard, Karen D. Tsuchiya, Elisabeth H. Villavicencio, Beryl A. Hatton
Supplementary Figure 1 from The Smo/Smo Model: Hedgehog-Induced Medulloblastoma with 90% Incidence and Leptomeningeal Spread
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0354347c25ca225859791ac9e861b5b9
https://doi.org/10.1158/0008-5472.22373822
https://doi.org/10.1158/0008-5472.22373822
Autor:
James M. Olson, Andrew R. Hallahan, Charles G. Eberhart, Donghoon Lee, Sue E. Knoblaugh, Stacey Hansen, Barbara Pullar, Sally Ditzler, Joel I. Pritchard, Karen D. Tsuchiya, Elisabeth H. Villavicencio, Beryl A. Hatton
Supplementary Figure 4 from The Smo/Smo Model: Hedgehog-Induced Medulloblastoma with 90% Incidence and Leptomeningeal Spread
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e80d1865cfd70158cc26aa13228b5ce
https://doi.org/10.1158/0008-5472.22373813
https://doi.org/10.1158/0008-5472.22373813
Autor:
James M. Olson, Phillip A. Beachy, Irwin D. Bernstein, Richard G. Ellenbogen, Thomas L. Russell, Beryl A. Hatton, Jennifer Stoeck, Mark Benson, Stacey Hansen, Joel I. Pritchard, Andrew R. Hallahan
To develop a genetically faithful model of medulloblastoma with increased tumor incidence compared with the current best model we activated the Sonic Hedgehog (Shh) pathway by transgenically expressing a constitutively active form of Smoothened in mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f70f02d1275ea5abcb5d4b88fde72b
https://doi.org/10.1158/0008-5472.c.6493643
https://doi.org/10.1158/0008-5472.c.6493643
Autor:
James M. Olson, Andrew R. Hallahan, Charles G. Eberhart, Donghoon Lee, Sue E. Knoblaugh, Stacey Hansen, Barbara Pullar, Sally Ditzler, Joel I. Pritchard, Karen D. Tsuchiya, Elisabeth H. Villavicencio, Beryl A. Hatton
Toward the goal of generating a mouse medulloblastoma model with increased tumor incidence, we developed a homozygous version of our ND2:SmoA1 model. Medulloblastomas form in 94% of homozygous Smo/Smo mice by 2 months of age. Tumor formation is, thus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::952a46181fae9db63590feb77eb25c6c
https://doi.org/10.1158/0008-5472.c.6497213
https://doi.org/10.1158/0008-5472.c.6497213
Autor:
Stacey Hansen, Mark R. Stroud, James M. Olson, Beryl A. Hatton, Sally Ditzler, Michael LeBlanc, M Ulrich, Joel I. Pritchard, E H Villavicencio, Barbara Pullar
Publikováno v:
Oncogene. 29:3865-3872
Dysregulated signal transduction via the notch pathway has been noted in human and mouse medulloblastoma studies. Gamma secretase inhibitors impair notch signaling by preventing the cleavage of transmembrane notch proteins into their active intracell
Autor:
Elisabeth H. Villavicencio, Dong-Hoon Lee, Barbara Pullar, Andrew R. Hallahan, Karen D. Tsuchiya, Stacey Hansen, Charles G. Eberhart, Sue E. Knoblaugh, Joel I. Pritchard, Beryl A. Hatton, James M. Olson, Sally Ditzler
Publikováno v:
Cancer Research. 68:1768-1776
Toward the goal of generating a mouse medulloblastoma model with increased tumor incidence, we developed a homozygous version of our ND2:SmoA1 model. Medulloblastomas form in 94% of homozygous Smo/Smo mice by 2 months of age. Tumor formation is, thus
Autor:
Joel I. Pritchard, James M. Olson
Publikováno v:
Cancer Genetics and Cytogenetics. 180:47-50
The Sonic hedgehog (Shh) pathway is aberrantly activated in a subset of the most common malignant pediatric brain tumor, medulloblastoma (MB). Shh pathway activity is measured by expression of the target genes in the GLI family, MYCN and PTCH1, a tum