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Autor:
Jason Fletcher, Joel Han
Publikováno v:
Journal of Human Capital. 13:585-634
Autor:
Anna Hakobyan, Mathilde Meyenberg, Nelli Vardazaryan, Joel Hancock, Loan Vulliard, Joanna I. Loizou, Jörg Menche
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109873- (2024)
Summary: Cancer is a multi-faceted disease with intricate relationships between mutagenic processes, alterations in cellular signaling, and the tissue microenvironment. To date, these processes have been largely studied in isolation. A systematic und
Externí odkaz:
https://doaj.org/article/6b65954581d04d98a91f73fe7f6964e5
Autor:
Sirintorn Stantripop, Sean Black, Ricardo D’Oliveira Albanus, S. L. Ho, John P. Didion, Beatrice B. Barnabas, Francis S. Collins, Brian P. Schmidt, Peter Orchard, Quino Maduro, Casandra Montemayor, Christina Sison, Karen L. Mohlke, Hannah J Perrin, K. Alaine Broadaway, Alice C. Young, Juyun Kim, Morgan Park, Laura J. Scott, Swarooparani Vadlamudi, Erin G. Schuetz, Karen Schandler, Narisu Narisu, James W. Thomas, Richelle Legaspi, Shelise Brooks, Gerard G. Bouffard, Joel Han, Federico Innocenti, Nancy Riebow, Vivek Rai, Lyudmila Dekhtyar, James C. Mullikin, Stephen C. J. Parker, Michael R. Erdos, Holly Coleman, Tingfen Yan, Catherine A. Masiello, Lori L. Bonnycastle, Jacqueline R. Idol, Amarjit S. Chaudhry, Jennifer C. McDowell, Kevin W Currin, Meghana Vemulapalli, Pamela J. Thomas, Amy S. Etheridge
Publikováno v:
Am J Hum Genet
Identifying the molecular mechanisms by which genome-wide association study (GWAS) loci influence traits remains challenging. Chromatin accessibility quantitative trait loci (caQTLs) help identify GWAS loci that may alter GWAS traits by modulating ch
Autor:
Joel Han, Jason M. Fletcher
Education mobility contributes to income mobility and is an important policy target but has received little attention. This paper documents trends (1982–2004) and geographical differences (across U...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39c4f60929c6d9f68c22502912059ef5
https://doi.org/10.3386/w25324
https://doi.org/10.3386/w25324
Autor:
Carsten G. Bönnemann, Francis J. McMahon, Quino Maduro, Alan T. Remaley, Brian P. Brooks, Sirintorn Stantripop, Jennifer C. McDowell, Kendall L. Umstead, Gerard G. Bouffard, Erin Turbitt, Catherine A. Masiello, Karen Schandler, Jeffrey Baron, Jennifer J. Johnston, Beatrice B. Barnabas, Richelle Legaspi, James W. Thomas, Holly Coleman, Eileen Pelayo, Barbara B. Biesecker, D. Nadine Dogbe, Ilias Alevizos, Joel Moss, W. Marston Linehan, Helen C. Su, Casandra Montemayor, Brian Schmidt, Alice C. Young, Morgan Park, Meghana Vemulapalli, Richard M. Siegel, Pamela J. Thomas, Chanthra Scharer, Youn Hee Jee, Deborah Nielsen, Carlos A. Zarate, Christina Sison, Leslie G. Biesecker, Alexis R Heidlebaugh, Sandra Donkervoort, Nancy Riebow, Shelise Brooks, James C. Mullikin, Teri A. Manolio, Julie C. Sapp, Xiaobin Guan, Ane Miren Sagardia, S. L. Ho, Kate Driscoll, Joel Han, Lyudmila Dekhtyar
© 2018 While consensus regarding the return of secondary genomic findings in the clinical setting has been reached, debate about such findings in the research setting remains. We developed a hybrid, research-clinical translational genomics process f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8f30234ebb7d1b8ff21c42057bf2c8
https://europepmc.org/articles/PMC6128311/
https://europepmc.org/articles/PMC6128311/
Publikováno v:
Journal of Diabetes, Vol 15, Iss 10, Pp 911-912 (2023)
Externí odkaz:
https://doaj.org/article/4d36ab80da6940ae859dd018e527d17d
Autor:
John R. Mascola, Quino Maduro, Christina Sison, Jenny McDowell, Chaim A. Schramm, Lawrence Shapiro, Brian P. Schmidt, Betty Benjamin, Karen Schandler, Cathy Masiello, Richelle Legaspi, Pam Thomas, James Thomas, Zizhang Sheng, Nisc Comparative Sequencing Program, Raymond Arthur Smith, Jessica Rosarda, Xiaobin Guan, Shelise Brooks, James C. Mullikin, Mila Dekhtyar, Nancy Riebow, Joel Han, Gerry Bouffard, Holly Coleman, Casandra Montemayor, Meg Vemulapalli, Mal Stantripop, Peter D. Kwong, Rui Kong, Alice Young, Morgan Park, Shi ling Ho
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology, Vol 8 (2017)
Somatic hypermutation (SHM) plays a critical role in the maturation of antibodies, optimizing recognition initiated by recombination of V(D)J genes. Previous studies have shown that the propensity to mutate is modulated by the context of surrounding
Autor:
Joel Hans Dongmo Keumo Jiazet, Jana Dlouha, Meriem Fournier, Bruno Moulia, François Ningre, Thiery Constant
Publikováno v:
Annals of Forest Science, Vol 79, Iss 1, Pp 1-13 (2022)
Abstract Key message This study presents the first attempt to quantify how the thigmomorphogenetic syndrome is involved in Fagus sylvatica L. tree growth responses to thinning. An experimental design preventing mechanosensing in half of the trees dem
Externí odkaz:
https://doaj.org/article/c8a5d4504fdd408ebd5b082b91e342f3
Autor:
Sean Lovett, Stephen C. J. Parker, Holly Coleman, Narisu Narisu, D. Leland Taylor, Morgan Park, Len A. Pennacchio, Taccara Johnson, Jenny McDowell, Baishali Maskeri, Meg Vemulapalli, Axel Visel, April Hargrove, Jennifer A. Akiyama, James Thomas, Michael R. Erdos, Cathy Masiello, Michael D. Gregory, Brian L. Schmidt, Peter S. Chines, Michael L. Stitzel, Quino Maduro, Betty Benjamin, Shi-ling Ho, Robert W. Blakesley, Xiaobin Guan, Francis S. Collins, Karen Schandler, Mal Stantripop, Casandra Montemayor, Richelle Legaspi, Jesse Becker, Kelly Lammerts van Bueren, Alice Young, Nancy Riebow, James C. Mullikin, Christina Sison, Jyoti Gupta, Nisc Comparative Sequencing Program, Mila Dekhtyar, Joel Han, Jose M. Orozco, Brian L. Black, Pam Thomas, Shelise Brooks, Gerry Bouffard
Publikováno v:
Proceedings of the National Academy of Sciences. 110:17921-17926
Chromatin-based functional genomic analyses and genomewide association studies (GWASs) together implicate enhancers as critical elements influencing gene expression and risk for common diseases. Here, we performed systematic chromatin and transcripto