Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Joel G.R. Weaver"'
Autor:
Melanie Paquin‐Gobeil, Sean Bennett, E. Celia Marginean, Fady Balaa, Jason K. Wasserman, Richard Mimeault, Guillaume Martel, Joel G.R. Weaver
Publikováno v:
HPB. 17:811-818
BackgroundIntraductal papillary neoplasms of the biliary tract (IPNB) and intracholecystic papillary neoplasms (ICPN) are rare tumours characterized by intraluminal papillary growth that can be associated with invasive carcinoma. Their natural histor
Autor:
Heather Hardin, Rolf P. G. van Heeswijk, Andrew D. Badley, Joel G.R. Weaver, Bogdan Zurakowski, Valerie L. Sim, Sheng T. Hou, Barbara N. Phenix, Peter J. Wettstein, Guido Kroemer, Catherine Brenner, Aurélien Deniaud, Agathe Tarze, Gary D. Bren, Morgane LeBras, Li Dong, Jessica Lallier, Andre G. Douen, Romano T. Kroemer, Tia C. Moffat, David H. Lynch, Susan X. Jiang, Mario Y. Morin, Steffany A. L. Bennett
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2005, 115, pp.1828-1838
Journal of Clinical Investigation, American Society for Clinical Investigation, 2005, 115, pp.1828-1838
Inhibitors of HIV protease have been shown to have antiapoptotic effects in vitro, yet whether these effects are seen in vivo remains controversial. In this study, we have evaluated the impact of the HIV protease inhibitor (PI) nelfinavir, boosted wi
Publikováno v:
The Journal of Heart and Lung Transplantation. 24:841-847
Background The process by which cardiac myocytes die during xenograft rejection is incompletely understood. The presence of cardiac myocyte apoptosis in discordant xenotransplant models has been noted, yet no investigators have examined whether a rel
Autor:
Keith Henry, Omobosola Akinsete, Craig T. January, Joel G.R. Weaver, Andrew D. Badley, Blake D. Anson, Michael J. Ackerman
Publikováno v:
The Lancet. 365:682-686
The HIV protease inhibitor class of antiretroviral drug causes unpredicted adverse effects by changing elements of normal cellular metabolism. A case of QT prolongation in a patient receiving protease inhibitors made us question whether these drugs m
Publikováno v:
The FASEB Journal. 18:1185-1191
The pathophysiology of sepsis involves excessive lymphocyte apoptosis, which correlates with adverse outcomes, and disordered cytokine production, which may promote host injury. As the protease inhibitor (PI) class of antiretroviral agents is known t
Publikováno v:
Journal of Ethnopharmacology. 90:57-62
Aqueous and alcohol extracts of Cordyceps sinensis (Berk) Succ. are used as a traditional medicine in China for the treatment of a wide range of diseases and are reported to have antioxidant and antiapoptotic properties. We therefore examined the abi
Autor:
John E. Kim, Timothy S. Gomez, Julian J. Lum, Andrew D. Badley, Nanci Hawley, Joel G.R. Weaver, David H. Lynch, Éric A. Cohen, Zilin Nie, Jaime Sanchez-Dardon, Xiaojian Yao, Oren J. Cohen, André A. Pilon, Michael Montpetit, Zhaoxia Chen
Publikováno v:
Journal of Clinical Investigation. 111:1547-1554
The absence of immune defects that occurs in the syndrome of long-term nonprogressive (LTNP) HIV infection offers insights into the pathophysiology of HIV-induced immune disease. The (H[F/S]RIG)(2) domain of viral protein R (Vpr) induces apoptosis an
Autor:
Joel G.R. Weaver, Andrew D. Badley, David J. McKean, Catherine J. Huntoon, Daniel B. Graham, Nanci Hawley, Michael P. Bell
Publikováno v:
AIDS (London, England). 19(14)
Objective: To determine the effects of antiretroviral therapy on thymic output independent of HIV infection. Methods: Thymic output was evaluated by quantifying signal joint T-cell receptor (TCR) recombination excision circles in peripheral blood lym