Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Joel G Winner"'
Autor:
Michael R. Jablonski, Lucas R Watterson, Joel G. Winner, Bryan Dechairo, Wang Yongbao, Gunselman Sandra, King Nina
Publikováno v:
Personalized Medicine. 15:189-197
Aim: The aim of this study was to validate the analytical performance of a combinatorial pharmacogenomics test designed to aid in the appropriate medication selection for neuropsychiatric conditions. Materials & methods: Genomic DNA was isolated from
Publikováno v:
Pharmacogenomics and Personalized Medicine
Eve S Fields,1 Raymond A Lorenz,2 Joel G Winner2 1Northwest Center for Community Mental Health, Reston, VA, USA; 2Assurex Health, Mason, OH, USA Abstract: This report describes two cases in which pharmacogenomic testing was utilized to guide medicati
Autor:
Susan Garavaglia, Andrew G Marshak, Seth Goldfarb, Josiah D. Allen, Joseph M Carhart, Joel G. Winner, Kelly K Parsons, Gabriela Lavezzari, C Anthony Altar, Bryan Dechairo
Publikováno v:
Current Medical Research and Opinion. 31:1633-1643
The objective of this project was to determine pharmacy cost savings and improvement in adherence based on a combinatorial pharmacogenomic test (CPGx ) in patients who had switched or added a new psychiatric medication after having failed monotherapy
Autor:
Joel G. Winner, C Anthony Altar, Daniel K. Hall-Flavin, Bryan Dechairo, Josiah D. Allen, Joseph M Carhart
Publikováno v:
Complex Psychiatry. 1:145-155
DNA of 258 patients with treatment-resistant depression was collected in three 8-10 week, two-arm, prospective clinical trials. Forty-four allelic variations were measured in genes for the cytochrome P450 (CYP) enzymes CYP2D6, CYPC19, and CYP1A2, the
Publikováno v:
Applied and Translational Genomics, Vol 5, Iss C, Pp 47-49 (2015)
Applied & Translational Genomics
Applied & Translational Genomics
Prescribing safe and effective medications is a challenge in psychiatry. While clinical use of pharmacogenomic testing for individual genes has provided some clinical benefit, it has largely failed to show clinical utility. However, pharmacogenomic t
Publikováno v:
Academic Psychiatry. 34:115-118
Objective The authors ascertained the amount of training in psychiatric genomics that is provided in North American psychiatric residency programs.
Autor:
Joel G, Winner, Bryan, Dechairo
Publikováno v:
The Yale Journal of Biology and Medicine
Pharmacogenomic testing in mental health has not yet reached its full potential. An important reason for this involves differentiating individual gene testing (IGT) from a combinatorial pharmacogenomic (CPGx) approach. With IGT, any given gene reveal
Autor:
Joel G. Winner, Josiah D. Allen, Joseph M Carhart, Daniel K. Hall-Flavin, C A Altar, Bryan Dechairo
Publikováno v:
The pharmacogenomics journal. 15(5)
In four previous studies, a combinatorial multigene pharmacogenomic test (GeneSight) predicted those patients whose antidepressant treatment for major depressive disorder resulted in poorer efficacy and increased health-care resource utilizations. He
Autor:
Maureen S. Drews, Joel G. Winner, David A. Mrazek, Josiah D. Allen, Brian D. Proctor, Joseph M Carhart, Linda L. Eisterhold, Daniel K. Hall-Flavin, Karen Snyder, Jennifer R. Geske
Publikováno v:
Pharmacogenetics and genomics. 23(10)
The objective was to evaluate the potential benefit of an integrated, five-gene pharmacogenomic test and interpretive report (GeneSight) for the management of psychotropic medications used to treat major depression in an outpatient psychiatric practi
Autor:
Joanna M. Biernacka, L L Eisterhold, Josiah D. Allen, J J Jordan, Maureen S. Drews, Joel G. Winner, David A. Mrazek, R S Nesheim, Daniel K. Hall-Flavin, Karen Snyder
Publikováno v:
Translational Psychiatry
The objective of this study was to evaluate the potential benefit of utilizing a pharmacogenomic testing report to guide the selection and dosing of psychotropic medications in an outpatient psychiatric practice. The non-randomized, open label, prosp