Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Joel F. Austin"'
Publikováno v:
Proceedings of the National Academy of Sciences. 101:5482-5487
Pyrroloindoline and bispyrroloindoline are a subclass of alkaloid structural motifs that commonly exhibit biological activity. An enantioselective organocatalytic approach to the synthesis of pyrroloindoline architecture is described. The addition–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1983e35ea72f785db5bec4592fd5f566
https://doi.org/10.1073/pnas.0308177101
https://doi.org/10.1073/pnas.0308177101
Autor:
Joel F. Austin, David W. C. MacMillan
Publikováno v:
ChemInform. 33
The indole framework has become widely identified as a “privileged” structure with representation in over 3000 natural isolates and 40 medicinal agents of diverse therapeutic action. A new strategy for asymmetric access to this important pharmaca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd4c2955625b3940d841ecaaf55f32be
https://doi.org/10.1002/chin.200229148
https://doi.org/10.1002/chin.200229148
Autor:
Joel F. Austin, David W. C. MacMillan
Publikováno v:
Journal of the American Chemical Society. 124(7)
The indole framework has become widely identified as a "privileged" structure with representation in over 3000 natural isolates and 40 medicinal agents of diverse therapeutic action. A new strategy for asymmetric access to this important pharmacaphor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7afc9a0fe7e5f3a26f15fc5c5dcd0182
https://pubmed.ncbi.nlm.nih.gov/11841277
https://pubmed.ncbi.nlm.nih.gov/11841277
Autor:
Yufen Zhao, Litai Zhang, Marco M. Gottardis, Liang Schweizer, Weifang Shan, Paul A. Elzinga, Georgia Cornelius, Yuwei Tang, Arvind Mathur, Ricardo M. Attar, Janet Dell-John, Maria Jure-Kunkel, Ashvin Gavai, Cheryl A. Rizzo, Mary Ellen Cvijic, Andrew Nation, Gregory D. Vite, Aaron Balog, Derek J. Norris, Donald Apanovitch, Gregg Masters, Mary T. Obermeier, Joel F. Austin, Melissa Yarde, Gennaro Dito, Lisa S. Sharma, William R. Foster, Wen-Ching Han, Punit Marathe, Celeste Twamley, Benjamin M. Johnson, Dauh-Rurng Wu
Publikováno v:
Cancer Research. 70:5782-5782
The development and progression of prostate cancer is known to be dependent on androgens and their signaling mediated by the androgen receptor (AR). The primary therapeutic intervention involves using agents that lower serum testosterone (e.g., LHRH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f9feeac1762608ab0e7b7354c858fe2
https://doi.org/10.1158/1538-7445.am10-5782
https://doi.org/10.1158/1538-7445.am10-5782