Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Joel Enas"'
Autor:
Vesselina Bozoukova, Alain Rolland, Jukka Hartikka, David Kurniadi, Antonio Nanci, Ji-Hyun Yi, Denis Rusalov, Joel Enas, Andrew J Geall
Publikováno v:
The journal of gene medicine. 10(7)
Plasmid DNA (pDNA) vaccines have generated significant interest for the prevention or treatment of infectious diseases. Broader applications may benefit from the identification of safe and potent vaccine adjuvants. This report describes the developme
Publikováno v:
Nucleic acids research. 30(8)
The large number of cytofectin and co-lipid combinations currently used for lipoplex-mediated gene delivery reflects the fact that the optimal cytofectin/ co-lipid combination varies with the application. The effects of structural changes in both cyt
Autor:
Vesselina Bozoukova, Gita Singh, Walter K. Nishioka, Loretta Sukhu, Mary K. Wloch, Carl J. Wheeler, Joel Enas, Marston Manthorpe, Jukka Hartikka, Marilyn Ferrari, Luane Reyes
Publikováno v:
Vaccine. 19(27)
Antigen specific immune responses were characterized after intramuscular immunization of BALB/c mice with 5 antigen encoding plasmid DNAs (pDNAs) complexed with Vaxfectin, a cationic lipid formulation. Vaxfectin increased IgG titers for all of the an
Publikováno v:
Nucleic acids research. 29(7)
Using a group of structurally related cytofectins, the effects of different vehicle constituents and mixing techniques on the physical properties and biological activity of lipoplexes were systematically examined. Physical properties were examined us
Autor:
Jukka Hartikka, Joel Enas, Michael Sawdey, Katja Tonsky, Loretta Sukhu, Carl J. Wheeler, Jon Norman, Marilyn Ferrari, Mary K. Wloch, Vesselina Bozoukova, Marston Manthorpe
Publikováno v:
Vaccine. 19(15-16)
This report characterizes Vaxfectin, a novel cationic and neutral lipid formulation which enhances antibody responses when complexed with an antigen-encoding plasmid DNA (pDNA). In mice, intramuscular injection of Vaxfectin formulated with pDNA encod