Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Joel E. Schlosburg"'
Autor:
Andreu Viader, Jacqueline L. Blankman, Peng Zhong, Xiaojie Liu, Joel E. Schlosburg, Christopher M. Joslyn, Qing-Song Liu, Aaron J. Tomarchio, Aron H. Lichtman, Dana E. Selley, Laura J. Sim-Selley, Benjamin F. Cravatt
Publikováno v:
Cell Reports, Vol 12, Iss 5, Pp 798-808 (2015)
The endocannabinoid 2-arachidonoylglycerol (2-AG) is a retrograde lipid messenger that modulates synaptic function, neurophysiology, and behavior. 2-AG signaling is terminated by enzymatic hydrolysis—a reaction that is principally performed by mono
Externí odkaz:
https://doaj.org/article/a58d2651f0fd4eff8581e58600acdec0
Autor:
Mohammed A. Mustafa, Justin L. Poklis, Kimberly N. Karin, Jayden A. Elmer, Joseph H. Porter, Victoria Parra, Dai Lu, Joel E. Schlosburg, Aron H. Lichtman
Publikováno v:
Cannabis and Cannabinoid Research.
Autor:
Julien C. Dodu, Rebecca K. Moncayo, M. Imad Damaj, Joel E. Schlosburg, Hamid I. Akbarali, Lesley D. O’Brien, Debra A. Kendall, Zhixing Wu, Dai Lu, Aron H. Lichtman
Publikováno v:
J Pharmacol Exp Ther
Opioid use disorder reflects a major public health crisis of morbidity and mortality in which opioid withdrawal often contributes to continued use. However, current medications that treat opioid withdrawal symptoms are limited by their abuse liabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349bdddb0e6324922bd50cedbb8da816
https://europepmc.org/articles/PMC8969135/
https://europepmc.org/articles/PMC8969135/
Autor:
Brendan J. Tunstall, Adriana Gregory-Flores, George F. Koob, Olivier George, Joel E. Schlosburg, Giordano de Guglielmo, Leandro F. Vendruscolo, M. Adrienne McGinn, Hazel Hunt, Barbara J. Mason
Publikováno v:
Neuropharmacology
Alcohol use disorder (AUD) is associated with the dysregulation of brain stress and reward systems, including glucocorticoid receptors (GRs). The mixed glucocorticoid/progesterone receptor antagonist mifepristone and selective GR antagonist CORT11317
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc96816bd8932829ce0f439c87e1cbd9
https://escholarship.org/uc/item/28w4t2f1
https://escholarship.org/uc/item/28w4t2f1
Autor:
Kim D. Janda, Atsushi Kimishima, Paul T. Bremer, Karen C. Collins, Bin Zhou, Joel E. Schlosburg
Publikováno v:
Angewandte Chemie. 128:3836-3839
Fentanyl is an addictive prescription opioid that is over 80 times more potent than morphine. The synthetic nature of fentanyl has enabled the creation of dangerous ‘designer drug’ analogues that escape toxicology screening, yet display comparabl
Autor:
Lois S. Akinola, Pretal P. Muldoon, Benjamin F. Cravatt, Aron H. Lichtman, Joel E. Schlosburg, Anu Mahadevan, Laura J. Sim-Selley, M. Imad Damaj
Publikováno v:
Neuropharmacology
Nicotine, the primary psychoactive component in tobacco, plays a major role in the initiation and maintenance of tobacco dependence and addiction, a leading cause of preventable death worldwide. An essential need thus exists for more effective pharma
Autor:
Benjamin F. Cravatt, David G. Stouffer, Fernando Rodríguez de Fonseca, Francisco Javier Pavón, Rémi Martin-Fardon, Eric P. Zorrilla, Loren H. Parsons, Ilham Polis, Marisa Roberto, Matthew W. Buczynski, Antonia Serrano, Luis A. Natividad, Joel E. Schlosburg
Negative emotional states that are associated with excessive alcohol intake, particularly anxiety-like states, have been linked to opponent processes in the central nucleus of the amygdala (CeA), affecting stress-related transmitters and monoamines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b26391f4dc961821dd34505ebf1e722
https://www.nature.com/articles/s41386-018-0055-3.pdf
https://www.nature.com/articles/s41386-018-0055-3.pdf
Autor:
Dana E. Selley, Aaron J. Tomarchio, Jacqueline L. Blankman, Xiaojie Liu, Peng Zhong, Joel E. Schlosburg, Christopher M. Joslyn, Benjamin F. Cravatt, Andreu Viader, Laura J. Sim-Selley, Aron H. Lichtman, Qing-song Liu
Publikováno v:
Cell Reports, Vol 12, Iss 5, Pp 798-808 (2015)
SummaryThe endocannabinoid 2-arachidonoylglycerol (2-AG) is a retrograde lipid messenger that modulates synaptic function, neurophysiology, and behavior. 2-AG signaling is terminated by enzymatic hydrolysis—a reaction that is principally performed
Autor:
Vivian Goodell, Eva R. Zamora-Martinez, Joseph K. Belanoff, Scott Edwards, Leandro F. Vendruscolo, Marian L. Logrip, Joel E. Schlosburg, Lauren G. Macshane, Barbara J. Mason, Olivier George, David Estey, George F. Koob, M. Adrienne McGinn, Pietro Paolo Sanna, Hazel Hunt
Publikováno v:
The Journal of clinical investigation, vol 125, iss 8
Alcoholism, or alcohol use disorder, is a major public health concern that is a considerable risk factor for morbidity and disability; therefore, effective treatments are urgently needed. Here, we demonstrated that the glucocorticoid receptor (GR) an
Autor:
Joel E. Schlosburg, Jonathan Z. Long, Steven G. Kinsey, Benjamin F. Cravatt, Sara R. Nass, Aron H. Lichtman
Publikováno v:
Journal of Neuroimmune Pharmacology. 10:364-370
Cannabinoid receptor agonists, such as Δ(9)-THC, the primary active constituent of Cannabis sativa, have anti-pyrogenic effects in a variety of assays. Recently, attention has turned to the endogenous cannabinoid system and how endocannabinoids, inc