Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Joel E. Schechter"'
Autor:
Joel E. Schechter, Lishan Su, Chia-Lin Chen, Keigo Machida, François-Loïc Cosset, Jeffrey Y. Huang, Takaji Wakita, Jae U. Jung, Yasuteru Kondo, Chun-Hsiang Wang, Stanley M. Tahara, Lin Zhou, Michael M. C. Lai
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8, pp.13882. ⟨10.1038/ncomms13882⟩
Nature Communications, 2017, 8, pp.13882. ⟨10.1038/ncomms13882⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8, pp.13882. ⟨10.1038/ncomms13882⟩
Nature Communications, 2017, 8, pp.13882. ⟨10.1038/ncomms13882⟩
B-cell infection by hepatitis C virus (HCV) has been a controversial topic. To examine whether HCV has a genetically determined lymphotropism through a co-receptor specific for the infection by lymphotropic HCV, we established an infectious clone and
Autor:
Melvin D. Trousdale, Austin K. Mircheff, Padmaja B. Thomas, Rui Hua Wei, Joel E. Schechter, D. M. Samant
Publikováno v:
Cornea. 31:693-701
PURPOSE Autologous peripheral blood lymphocytes, activated in a mixed cell reaction when cocultured with purified rabbit lacrimal epithelial cells, are known to induce a severe autoimmune dacryoadenitis when injected directly into the donor animal's
Autor:
D. M. Samant, Melvin D. Trousdale, Douglas Stevenson, Joel E. Schechter, Shivaram Selvam, John D Gray, Yanru Wang, Austin K. Mircheff, Padmaja B. Thomas
Publikováno v:
Cornea. 29:1153-1162
PURPOSE To test whether CD4+ T cells proliferate in mixed cell reactions with autologous lacrimal gland (LG) acinar cells and whether these cells can autoadoptively transfer disease. METHODS Purified acinar cells were gamma irradiated and cocultured
Publikováno v:
The Ocular Surface. 8:111-134
Research into the physiological processes governing both normal and abnormal functions of the lacrimal gland has used animal models to provide insights that might be applied to improving our understanding of human disease and designing of beneficial
Autor:
Yanru Wang, M. De Saint Jean, Austin K. Mircheff, Joel E. Schechter, Melvin D. Trousdale, T. Nakamura
Publikováno v:
Scandinavian Journal of Immunology. 70:53-62
Lacrimal epithelial cells appear to constitutively secrete autoantigens to their underling stroma. The present experiments address the hypothesis that they also secrete soluble factors that regulate immune responses. Epithelial cells, spleen cells an
Autor:
D. M. Samant, Padmaja B. Thomas, Z. Zhu, Melvin D. Trousdale, Sang W. Song, Shivaram Selvam, Douglas Stevenson, Yanru Wang, Austin K. Mircheff, Joel E. Schechter, Samuel C. Yiu
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 25:285-291
To use a rabbit model of induced autoimmune dacryoadenitis to evaluate the efficacy of topical ophthalmic cyclosporine A (CsA).Autoimmune dacryoadenitis was induced by injecting autologous peripheral blood lymphocytes, which had been activated in a m
Autor:
Shivaram Selvam, S.W. Song, Melvin D. Trousdale, Douglas Stevenson, Joel E. Schechter, Austin K. Mircheff, D. M. Samant, Padmaja B. Thomas, Z. Zhu
Publikováno v:
Journal of Autoimmunity. 31:116-122
Autologous peripheral blood lymphocytes (PBL), activated in a mixed cell reaction when co-cultured with purified rabbit lacrimal epithelial cells, are known to induce a Sjőgren’s-like autoimmune dacryoadenitis and keratoconjunctivitis when injecte
Autor:
Yanru Wang, Sarah F. Hamm-Alvarez, Barbara Petridou, T. Nakamura, Ameae M. Walker, C.T. Chiu, Austin K. Mircheff, Joel E. Schechter, Melvin D. Trousdale
Publikováno v:
Experimental Eye Research
Experimental Eye Research, Elsevier, 2007, 85 (6), pp.749-761
Experimental Eye Research, Elsevier, 2007, 85 (6), pp.749-761
The rabbit lacrimal gland undergoes an immunophysiological transformation during pregnancy, reminiscent of that of the mammary gland as it prepares to deliver secretory IgA into the nascent fluid product. The contents of TGF-beta and prolactin (PRL)
Publikováno v:
Ophthalmic Research. 40:49-52
Aim: To develop a local approach to study rabbit lacrimal secretion in situ by administering specific secretagogues directly onto the lacrimal gland (LG). Methods: After the rabbit has been anesthetized, the inferior bulbar conjunctiva and underlying
Autor:
Silvia R. da Costa, Sarah F. Hamm-Alvarez, Joel E. Schechter, Eunbyul Sou, Galina V. Jerdeva, Kaijin Wu
Publikováno v:
Experimental Eye Research. 83:84-96
The acinar epithelial cells of the lacrimal gland are responsible for the production, packaging and regulated exocytosis of tear proteins into ocular surface fluid. This review summarizes new findings on the mechanisms of exocytosis in these cells. P