Modeling Epiblast Shape in Implanting Mammalian Embryos

Autor: Joel, Dokmegang

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2490

An indispensable prerequisite of mammalian development is successful morphogenesis in the epiblast, the embryonic tissue that gives rise to all differentiated cells of the adult mammal. The right control of both epiblast morphogenesis and the events

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::79686de0c052c33f239aaf1e0756ed19
https://pubmed.ncbi.nlm.nih.gov/35486253

Quantification of cell behaviors and computational modelling show that cell directional behaviors drive zebrafish pectoral fin morphogenesis

Autor: Matteo Cavaliere, Elena Kardash, René Doursat, Nadine Peyriéras, Joel Dokmegang, Thierry Savy, Hanh Nguyen

Publikováno v: Bioinformatics
Bioinformatics, Oxford University Press (OUP), 2021, 37 (18), pp.2946-2954. ⟨10.1093/bioinformatics/btab201⟩
Bioinformatics, 2021, 37 (18), pp.2946-2954. ⟨10.1093/bioinformatics/btab201⟩

Motivation: Understanding the mechanisms by which the zebrafish pectoral fin develops is expected to produce insights on how vertebrate limbs grow from a 2D cell layer to a 3D structure. Two mechanisms have been proposed to drive limb morphogenesis i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157bd82e4e19f599868f1f5192551749
https://e-space.mmu.ac.uk/627453/

Computational modelling unveils how epiblast remodelling and positioning rely on trophectoderm morphogenesis during mouse implantation

Autor: René Doursat, Joel Dokmegang, Liangxiu Han, Matteo Cavaliere, Moi Hoon Yap

Publikováno v: PLoS ONE
PLOS ONE
PLoS ONE, Vol 16, Iss 7, p e0254763 (2021)

Understanding the processes by which the mammalian embryo implants in the maternal uterus is a long-standing challenge in embryology. New insights into this morphogenetic event could be of great importance in helping, for example, to reduce human inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a535d5018f752f77a29b34b4a50730f8
https://doi.org/10.1371/journal.pone.0254763