Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Joel D. Moore"'
Autor:
Joel D. Moore, John A. Donaldson
Publikováno v:
Journal of Agrarian Change.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c790cea91fa8fcf6cf02de1f3ae95de3
https://doi.org/10.1111/joac.12543
https://doi.org/10.1111/joac.12543
Autor:
Jia Lei, Joon Jung, Sylvie G. Bernier, Joel D. Moore, Glen Rennie, Mermerian Ara, Nicholas Robert Perl, Thomas Wai-Ho Lee, Andrew Carvalho, Barden Timothy Claude, Peter Germano, Jenny Tobin, Colleen Hudson, Renee Deming, Rajesh R. Iyengar, Takashi Nakai, G-Yoon Jamie Im, Paul A. Renhowe, Daniel P. Zimmer, Elise Kim
Publikováno v:
Bioorganicmedicinal chemistry letters. 40
Soluble guanylate cyclase (sGC) is a clinically validated therapeutic target in the treatment of pulmonary hypertension. Modulators of sGC have the potential to treat diseases that are affected by dysregulation of the NO-sGC-cGMP signal transduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9de2bad2e2d41649c98451bf1e9a94
https://pubmed.ncbi.nlm.nih.gov/33662540
https://pubmed.ncbi.nlm.nih.gov/33662540
Autor:
Sylvie G. Bernier, G. Todd Milne, Joel D. Moore, Daniel P. Zimmer, Renee Sarno, Sheila Ranganath, Kim Tang, Albert T. Profy, Jaime L. Masferrer, G-Yoon Jamie Im, Guang Liu, James E. Sheppeck, Courtney Shea, Ali R. Banijamali, Sarah Jacobson, James Wakefield, Jenny Tobin, Peter Germano, Kim Long, Kristine Sykes, Mark G. Currie, Joy Miyashiro
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 365(3)
Soluble guanylate cyclase (sGC), a key signal-transduction enzyme, increases the conversion of guanosine-5'-triphosphate to cGMP upon binding of nitric oxide (NO). Endothelial dysfunction and/or reduced NO signaling have been implicated in cardiovasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c4901b890abc311faa878fa692a045
https://pubmed.ncbi.nlm.nih.gov/29643251
https://pubmed.ncbi.nlm.nih.gov/29643251
Autor:
Joel D. Moore, Kristie Sykes, Peter Germano, Kimberly Long, Jenny Tobin, Jaime L. Masferrer, Robert Jefferson, Erik Solberg, James E. Sheppeck, Takashi Nakai, Samuel Rivers, Courtney Shea, James Wakefield
Publikováno v:
The FASEB Journal. 29
Soluble guanylate cyclase (sGC) stimulators have the potential to treat a variety of cardiovascular diseases via the nitric oxide (NO)-sGC-cyclic guanosine monophosphate (cGMP) pathway. Ironwood Ph...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df097b2d220e2b962e9d6f170a01ae92
https://doi.org/10.1096/fasebj.29.1_supplement.623.5
https://doi.org/10.1096/fasebj.29.1_supplement.623.5
Publikováno v:
Organic Letters. 6:2657-2660
The development of high-load, soluble oligomeric sulfonate esters, generated via ROM polymerization, and their utility in the facile benzylation of an array of amines is reported. These polymeric sulfonate esters exist as free-flowing powders, are st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f419130a784174444e30c825ee6338
https://doi.org/10.1021/ol049209y
https://doi.org/10.1021/ol049209y
Publikováno v:
Tetrahedron Letters. 45:417-420
A new strategy employing an Ugi four-component reaction and a microwave-assisted intramolecular Heck cyclization in a sequential fashion to access an array of N-containing heterocycles is reported. The two-step sequence generated compounds of signifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f25d64eff64d94e7b5a10a329bbc0d06
https://doi.org/10.1016/j.tetlet.2003.10.147
https://doi.org/10.1016/j.tetlet.2003.10.147
Autor:
Paul R. Hanson, Joel D. Moore
Publikováno v:
Tetrahedron: Asymmetry. 14:873-880
The investigation of substituent effects in the double diastereotopic differentiation of substituted α-diazophosphonates using intramolecular cyclopropanation catalyzed by Rh 2 (OAc) 4 is reported. Carbene facial selectivity in these transformations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77ad5831a7ce03600bc2c527365e6761
https://doi.org/10.1016/s0957-4166(03)00081-8
https://doi.org/10.1016/s0957-4166(03)00081-8
Publikováno v:
The Journal of Organic Chemistry. 67:8123-8129
A transition metal-catalyzed/Curtius rearrangement sequence toward the development of conformationally constrained alpha-Boc-aminophosphonates 2-6 is described. An approach using the versatile tert-butylphosphonoacetate moieties 1a and 1b to derive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db859ba73b0884b6c10778f0dd34c9c2
https://doi.org/10.1021/jo0262208
https://doi.org/10.1021/jo0262208
Publikováno v:
Organic Letters. 4:2357-2360
[reaction: see text] A double diastereotopic differentiation strategy on a phosphonoacetate template is described. The approach utilizes Rh(2)(OAc)(4)-catalyzed intramolecular cyclopropanation (ICP) employing the (R)-pantolactone auxiliary in the est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc611eeca90d26e2261ef7996e7008b7
https://doi.org/10.1021/ol026080o
https://doi.org/10.1021/ol026080o
Publikováno v:
Synlett. 2001:0605-0608
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e10db77d1162cd4ec714bf937bd771ed
https://doi.org/10.1055/s-2001-13374
https://doi.org/10.1055/s-2001-13374