Zobrazeno 1 - 10
of 282
pro vyhledávání: '"Joel C Bornstein"'
Autor:
Haozhe Wang, Kristian Barry, Aidil Zaini, Gillian Coakley, Mati Moyat, Carmel P Daunt, Lakshanie C Wickramasinghe, Rossana Azzoni, Roxanne Chatzis, Bibek Yumnam, Mali Camberis, Graham Le Gros, Olaf Perdijk, Jaime P P Foong, Joel C Bornstein, Benjamin J Marsland, Nicola L Harris
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1011766 (2024)
Intestinal helminth infection triggers a type 2 immune response that promotes a 'weep-and sweep' response characterised by increased mucus secretion and intestinal hypermotility, which function to dislodge the worm from its intestinal habitat. Recent
Externí odkaz:
https://doaj.org/article/36ebdfe1069a4be6ad32d6752f7b22f2
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 6, p e1009717 (2022)
Transmission between neurons in the extensive enteric neural networks of the gut involves synaptic potentials with vastly different time courses and underlying conductances. Most enteric neurons exhibit fast excitatory post-synaptic potentials (EPSPs
Externí odkaz:
https://doaj.org/article/74aaebd734674d34aef792c1d719eb21
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Gastrointestinal (GI) side-effects of chemotherapy are a debilitating and often overlooked clinical hurdle in cancer management. Chemotherapy-induced constipation (CIC) and diarrhoea (CID) present a constant challenge in the efficient and tolerable t
Externí odkaz:
https://doaj.org/article/ba751b3a8cd74d2aaf4e670add959c99
Autor:
Caroline S Hirst, Jaime P P Foong, Lincon A Stamp, Emily Fegan, Stephan Dent, Edward C Cooper, Alan E Lomax, Colin R Anderson, Joel C Bornstein, Heather M Young, Sonja J McKeown
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0123436 (2015)
The enteric nervous system arises from neural crest-derived cells (ENCCs) that migrate caudally along the embryonic gut. The expression of ion channels by ENCCs in embryonic mice was investigated using a PCR-based array, RT-PCR and immunohistochemist
Externí odkaz:
https://doaj.org/article/18e2ce8bc6214ba3a13c98a8aa9cae69
Publikováno v:
Frontiers in Neuroscience, Vol 8 (2014)
The roles of 5-HT3 and 5-HT4 receptors in the modulation of intestinal propulsion by luminal application of 5-HT and augmentation of endogenous 5-HT effects were studied in segments of guinea-pig ileum in vitro. Persistent propulsive contractions evo
Externí odkaz:
https://doaj.org/article/506ec80d73b94ea19504329658344412
Autor:
Linah eWafai, Mohammadali eTaher, Valentina eJovanovska, Joel C Bornstein, Crispin R Dass, Kulmira eNurgali
Publikováno v:
Frontiers in Neuroscience, Vol 7 (2013)
Oxaliplatin, an anti-cancer chemotherapeutic agent used for the treatment of colorectal cancer, commonly causes gastrointestinal side-effects such as constipation, diarrhoea, nausea and vomiting. Damage to enteric neurons may underlie some of these g
Externí odkaz:
https://doaj.org/article/263832e61cdc485187549959f40f5020
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e40840 (2013)
BACKGROUND: The nature of synaptic transmission at functionally distinct synapses in intestinal reflex pathways has not been fully identified. In this study, we investigated whether transmission between interneurons in the descending inhibitory pathw
Externí odkaz:
https://doaj.org/article/d4212cb5c60941d68c34d878183cd9dc
Autor:
Vaughan G Macefield, Joel C Bornstein
Publikováno v:
Frontiers in Neuroscience, Vol 6 (2012)
Externí odkaz:
https://doaj.org/article/56de26d2635f4860add3ef084eb99b66
Autor:
Joel C Bornstein
Publikováno v:
Frontiers in Neuroscience, Vol 6 (2012)
Externí odkaz:
https://doaj.org/article/8860c04b86db418b9490d138d30e604e
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19597 (2011)
After a meal, the gastrointestinal tract exhibits a set of behaviours known as the fed state. A major feature of the fed state is a little understood motor pattern known as segmentation, which is essential for digestion and nutrient absorption. Segme
Externí odkaz:
https://doaj.org/article/eacebae1dc894c20a411b68d07feae5b