Výsledky vyhledávání - "Joel A Pedersen"

Akademický článek

Diagnostic testing of chronic wasting disease in white-tailed deer (Odocoileus virginianus) by RT-QuIC using multiple tissues.

Autor: Kate R Burgener, Stuart S Lichtenberg, Aaron Lomax, Daniel J Storm, Daniel P Walsh, Joel A Pedersen

Publikováno v: PLoS ONE, Vol 17, Iss 11, p e0274531 (2022)

Chronic wasting disease (CWD) is a fatal prion disease affecting cervids (deer, elk, moose). Current methods to monitor individual disease state include highly invasive antemortem rectal biopsy or postmortem brain biopsy. Efficient, sensitive, and se

Externí odkaz: https://doaj.org/article/8dad34d9a4bf49798b11755a964e3f2b

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Akademický článek

Mineral licks as environmental reservoirs of chronic wasting disease prions.

Autor: Ian H Plummer, Chad J Johnson, Alexandra R Chesney, Joel A Pedersen, Michael D Samuel

Publikováno v: PLoS ONE, Vol 13, Iss 5, p e0196745 (2018)

Chronic wasting disease (CWD) is a fatal neurodegenerative disease of deer, elk, moose, and reindeer (cervids) caused by misfolded prion proteins. The disease has been reported across North America and recently discovered in northern Europe. Transmis

Externí odkaz: https://doaj.org/article/b9da15bcbf1844a99308f252de4891da

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Akademický článek

Highly efficient amplification of chronic wasting disease agent by protein misfolding cyclic amplification with beads (PMCAb).

Autor: Chad J Johnson, Judd M Aiken, Debbie McKenzie, Michael D Samuel, Joel A Pedersen

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e35383 (2012)

Protein misfolding cyclic amplification (PMCA) has emerged as an important technique for detecting low levels of pathogenic prion protein in biological samples. The method exploits the ability of the pathogenic prion protein to convert the normal pri

Externí odkaz: https://doaj.org/article/5633530c69b24d148a07cca5ee68f306

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Akademický článek

Oral transmissibility of prion disease is enhanced by binding to soil particles.

Autor: Christopher J Johnson, Joel A Pedersen, Rick J Chappell, Debbie McKenzie, Judd M Aiken

Publikováno v: PLoS Pathogens, Vol 3, Iss 7, p e93 (2007)

Soil may serve as an environmental reservoir for prion infectivity and contribute to the horizontal transmission of prion diseases (transmissible spongiform encephalopathies [TSEs]) of sheep, deer, and elk. TSE infectivity can persist in soil for yea

Externí odkaz: https://doaj.org/article/c2ba86d72c8b42cd8c8d98d68715a01e

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Akademický článek

Prions adhere to soil minerals and remain infectious.

Autor: Christopher J Johnson, Kristen E Phillips, Peter T Schramm, Debbie McKenzie, Judd M Aiken, Joel A Pedersen

Publikováno v: PLoS Pathogens, Vol 2, Iss 4, p e32 (2006)

An unidentified environmental reservoir of infectivity contributes to the natural transmission of prion diseases (transmissible spongiform encephalopathies [TSEs]) in sheep, deer, and elk. Prion infectivity may enter soil environments via shedding fr

Externí odkaz: https://doaj.org/article/979ce637b2e34e1f95ce43808b551a2b

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Nanoparticle tracking analysis and statistical mixture distribution analysis to quantify nanoparticle–vesicle binding

Autor: Isabel U. Foreman-Ortiz, Ting Fung Ma, Brandon M. Hoover, Meng Wu, Catherine J. Murphy, Regina M. Murphy, Joel A. Pedersen

Publikováno v: Journal of Colloid and Interface Science. 615:50-58

Nanoparticle tracking analysis (NTA) is a single particle tracking technique that in principle provides a more direct measure of particle size distribution compared to dynamic light scattering (DLS). Here, we demonstrate how statistical mixture distr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6757485bbba7bd39a6722704c56f9b5b
https://doi.org/10.1016/j.jcis.2022.01.141

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Predicting the Physicochemical Properties and Biological Activities of Monolayer-Protected Gold Nanoparticles Using Simulation-Derived Descriptors

Autor: Alex K. Chew, Joel A. Pedersen, Reid C. Van Lehn

Publikováno v: ACS Nano. 16:6282-6292

Gold nanoparticles are versatile materials for biological applications because their properties can be modulated by assembling ligands on their surface to form monolayers. However, the physicochemical properties and behaviors of monolayer-protected n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef30acb86882631088f01b904172e596
https://doi.org/10.1021/acsnano.2c00301

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Sulfolipid density dictates the extent of carbon nanodot interaction with chloroplast membranes

Autor: Kyoungtea Kim, Su-Ji Jeon, Peiguang Hu, Caroline M. Anastasia, William F. Beimers, Juan Pablo Giraldo, Joel A. Pedersen

Publikováno v: Environmental Science: Nano. 9:2691-2703

The relative abundance of sulfoquinovosyl diacylglycerol (SQDG) in model chloroplast membranes dictates both the affinity for and capacity of the membrane to interact with positively charged carbon nanodots (CNDs).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4957e102b2cc3094ed91fc52965139fa
https://doi.org/10.1039/d2en00158f

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