Výsledky vyhledávání - "Joel A Mefford"

Akademický článek

Varied performance of picture description task as a screening tool across MCI subtypes.

Autor: Joel A Mefford, Zilong Zhao, Leah Heilier, Man Xu, Guifeng Zhou, Rachel Mace, Kelly L Sloane, Shannon M Sheppard, Shenly Glenn

Publikováno v: PLOS Digital Health, Vol 2, Iss 3, p e0000197 (2023)

A picture description task is a component of Miro Health's platform for self-administration of neurobehavioral assessments. Picture description has been used as a screening tool for identification of individuals with Alzheimer's disease and mild cogn

Externí odkaz: https://doaj.org/article/2f11aeb3bb68445d952a4404219d4362

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Akademický článek

Association of the innate immunity and inflammation pathway with advanced prostate cancer risk.

Autor: Rémi Kazma, Joel A Mefford, Iona Cheng, Sarah J Plummer, Albert M Levin, Benjamin A Rybicki, Graham Casey, John S Witte

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e51680 (2012)

Prostate cancer is the most frequent and second most lethal cancer in men in the United States. Innate immunity and inflammation may increase the risk of prostate cancer. To determine the role of innate immunity and inflammation in advanced prostate

Externí odkaz: https://doaj.org/article/62a6b80d2d5646b8b91c6ddcb4bb96e6

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Validation of a Mobile, Sensor-based Neurobehavioral Assessment With Digital Signal Processing and Machine-learning Analytics

Autor: Kelly L, Sloane, Joel A, Mefford, Zilong, Zhao, Man, Xu, Guifeng, Zhou, Rachel, Fabian, Amy E, Wright, Shenly, Glenn

Publikováno v: Cognitive and Behavioral Neurology. 35:169-178

The Miro Health Mobile Assessment Platform consists of self-administered neurobehavioral and cognitive assessments that measure behaviors typically measured by specialized clinicians.To evaluate the Miro Health Mobile Assessment Platform's concurrent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690a18a1cf6f69f4e521679592f9a4f1
https://doi.org/10.1097/wnn.0000000000000308

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Supplementary Data from A Large-Scale Association Study Detects Novel Rare Variants, Risk Genes, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility

Figure S1-S6, Table S1-S10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3832c1cc5a2ef438ce0e17b1f933c0
https://doi.org/10.1158/0008-5472.22428541.v1

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Supplementary Figures S1-S5 from Mutational Landscape of Aggressive Prostate Tumors in African American Men

Autor: John S. Witte, Benjamin A. Rybicki, William J. Catalona, Brian T. Helfand, Dhananjay Chitale, Albert M. Levin, Yalei Chen, Vy Ngo, Jeffrey P. Simko, Joel A. Mefford, Rémi Kazma, Niall J. Cardin, Thomas J. Hoffmann, Pamela L. Paris, Karla J. Lindquist

Allele frequencies for 128 ancestry informative single nucleotide polymorphisms, with correlations (r values) between Structure model estimates and actual allele frequencies for our 24 African American (AA) patients, plus 146 other AA and 204 Europea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040eb4f60691274aaf64a569bade804f
https://doi.org/10.1158/0008-5472.22410402

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Supplementary Table S2 from Mutational Landscape of Aggressive Prostate Tumors in African American Men

Individual patient Genomic Evaluators of Metastatic Prostate Cancer (GEMCaP) scores and test results, with and without copy-neutral losses.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085134039470d4f156c1e5cb77584e05
https://doi.org/10.1158/0008-5472.22410393

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Data from Mutational Landscape of Aggressive Prostate Tumors in African American Men

Prostate cancer is the most frequently diagnosed and second most fatal nonskin cancer among men in the United States. African American men are two times more likely to develop and die of prostate cancer compared with men of other ancestries. Previous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597882e8438076d3e8d9f003d1aa2f62
https://doi.org/10.1158/0008-5472.c.6507984.v1

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Data from A Large-Scale Association Study Detects Novel Rare Variants, Risk Genes, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility

To identify rare variants associated with prostate cancer susceptibility and better characterize the mechanisms and cumulative disease risk associated with common risk variants, we conducted an integrated study of prostate cancer genetic etiology in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39deb2175dd5fb54b8fc87beeb38bb7b
https://doi.org/10.1158/0008-5472.c.6513064

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Detecting gene-environment interactions in human birth defects: Study designs and statistical methods

Autor: Caroline G, Tai, Rebecca E, Graff, Jinghua, Liu, Michael N, Passarelli, Joel A, Mefford, Gary M, Shaw, Thomas J, Hoffmann, John S, Witte

Publikováno v: Birth defects research. Part A, Clinical and molecular teratology. 103(8)

The National Birth Defects Prevention Study (NBDPS) contains a wealth of information on affected and unaffected family triads, and thus provides numerous opportunities to study gene-environment interactions (G×E) in the etiology of birth defect outc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1f463537b7a95d875fdc7ce19384b296
https://pubmed.ncbi.nlm.nih.gov/26010994

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Joint association testing of common and rare genetic variants using hierarchical modeling

Autor: Niall J, Cardin, Joel A, Mefford, John S, Witte

Publikováno v: Genetic epidemiology. 36(6)

New sequencing technologies provide an opportunity for assessing the impact of rare and common variants on complex diseases. Several methods have been developed for evaluating rare variants, many of which use weighted collapsing to combine rare varia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::64e52d61ab91c0ef76cc6bc561c1d558
https://pubmed.ncbi.nlm.nih.gov/22807252

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