Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Joel A, Spencer"'
Autor:
Nastaran Abbasizadeh, Christian S. Burns, Ruth Verrinder, Farhad Ghazali, Negar Seyedhassantehrani, Joel A. Spencer
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Preparative regimens before Hematopoietic Cell Transplantation (HCT) damage the bone marrow (BM) microenvironment, potentially leading to secondary morbidity and even mortality. The precise effects of cytotoxic preconditioning on bone and BM remodeli
Externí odkaz:
https://doaj.org/article/eae7fe48cd434246837e051b7c153c31
Autor:
Negar Seyedhassantehrani, Christian S Burns, Ruth Verrinder, Victoria Okafor, Nastaran Abbasizadeh, Joel A Spencer
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0307962 (2024)
The thymus, a key organ in the adaptive immune system, is sensitive to a variety of insults including cytotoxic preconditioning, which leads to atrophy, compression of the blood vascular system, and alterations in hemodynamics. Although the thymus ha
Externí odkaz:
https://doaj.org/article/231c340dc8ce43cf8334479004639f42
Autor:
Toshihiko Oki, Francois Mercier, Hiroki Kato, Yookyung Jung, Thomas O. McDonald, Joel A. Spencer, Michael C. Mazzola, Nick van Gastel, Charles P. Lin, Franziska Michor, Toshio Kitamura, David T. Scadden
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The role of mTORC1 in AML has not yet been proven due to the mixed results of its inhibitors in clinical trials. Here the authors show the real-time dynamics of the mTORC1 pathway in association with AML growth and response to chemotherapy with fluor
Externí odkaz:
https://doaj.org/article/349ab8eb498d4321b364ef08df2b3bd9
Autor:
Betsabel Chicana, Nastaran Abbasizadeh, Christian Burns, Hanna Taglinao, Joel A. Spencer, Jennifer O. Manilay
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The contributions of skeletal cells to the processes of B cell development in the bone marrow (BM) have not been completely described. The von-Hippel Lindau protein (VHL) plays a key role in cellular responses to hypoxia. Previous work showed that Dm
Externí odkaz:
https://doaj.org/article/2fd8c79095e344f8af8d5b8706a0007c
Autor:
Juwell W. Wu, Yookyung Jung, Shu-Chi A. Yeh, Yongwan Seo, Judith M. Runnels, Christian S. Burns, Toshihide Mizoguchi, Keisuke Ito, Joel A. Spencer, Charles P. Lin
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
Advances in intravital microscopy (IVM) have enabled the studies of cellular organization and dynamics in the native microenvironment of intact organisms with minimal perturbation. The abilities to track specific cell populations and monitor their in
Externí odkaz:
https://doaj.org/article/a2f7fc3e29964264b1f167ed039fe0bb
Autor:
MUSTAFA SOFTA, EREN ŞAHİNER, HASAN SÖZBİLİR, JOEL QG SPENCER, MEHMET UTKU, MEHMET FATİH BÜYÜKTOPCU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a028c631da03f88e44168f1876bc52a
https://avesis.deu.edu.tr/publication/details/bd1a2af8-60e9-4d53-9cb4-df599e845e64/oai
https://avesis.deu.edu.tr/publication/details/bd1a2af8-60e9-4d53-9cb4-df599e845e64/oai
Autor:
Karin Gustafsson, Sergey Isaev, Kameron A. Kooshesh, Ninib Baryawno, Konstantinos D. Kokkaliaris, Nicolas Severe, Ting Zhao, Elizabeth W. Scadden, Joel A. Spencer, Christian Burns, Kumaran Akilan, Nikolaos Barkas, Hayalneh Gessessew, Charles P. Lin, Peter V. Kharchenko, David T. Scadden
Thymic atrophy and the progressive immune decline that accompanies it is a major health problem, chronically with age and acutely with immune injury. No solution has been defined. Here we demonstrate that one of the three mesenchymal cell subsets ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6c0bfb6f15ea8e6e215309d5b9b5b02
https://doi.org/10.1101/2022.10.12.511184
https://doi.org/10.1101/2022.10.12.511184
Publikováno v:
TURKISH JOURNAL OF EARTH SCIENCES. 30:359-378
The timing of the deposition of the well-preserved Quaternary marine terraces in the coastal region of northeastern Turkey are crucial in understanding the Quaternary tectonics of the Pontides. The chronology of raised marine terraces between Trabzon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f44094a37aaf84cbff3ab5111bb2cc
https://doi.org/10.3906/yer-2005-21
https://doi.org/10.3906/yer-2005-21
Publikováno v:
Blood Cancer Discovery. 4:A26-A26
Hematopoietic Cell Transplantation (HCT) is a frequently used treatment for hematologic malignancies such as acute myeloid leukemia, multiple myeloma, lymphoma and non-malignant diseases. Preparative regimens before HCT damage the Bone Marrow (BM) ni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7b612f09832598128af9d24de1ab64f
https://doi.org/10.1158/2643-3249.aml23-a26
https://doi.org/10.1158/2643-3249.aml23-a26
Autor:
Sergei A. Vinogradov, Negar Seyedhassantehrani, Archibald S. Perkins, Tatiana V. Esipova, Azucena Ramos, Guoji Guo, Charles P. Lin, Raffaele A. Calogero, Joel A. Spencer, Riccardo Panero, Constantina Christodoulou, Stuart H. Orkin, Sarah Rudzinskas, Raphaël Turcotte, Shu-Chi A. Yeh, Timm Schroeder, Konstantinos D. Kokkaliaris, Yi Zhang, Fernando D. Camargo
Publikováno v:
Nature
The biology of hematopoietic stem cells (HSCs) has predominantly been studied under transplantation conditions1,2. Particularly challenging has been the study of dynamic HSC behaviors given that live animal HSC visualization in the native niche still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a4eedb6ab64fc6eed1e10bd3e42e40
http://europepmc.org/articles/PMC7021587
http://europepmc.org/articles/PMC7021587