Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Joel, Simrén"'
Autor:
Lovisa Bark, Ing-Marie Larsson, Ewa Wallin, Joel Simrén, Henrik Zetterberg, Miklos Lipcsey, Robert Frithiof, Elham Rostami, Michael Hultström
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract A high proportion of patients with coronavirus disease 2019 (COVID-19) experience post-acute COVID-19, including neuropsychiatric symptoms. Objective signs of central nervous system (CNS) damage can be investigated using CNS biomarkers such
Externí odkaz:
https://doaj.org/article/b2d3d955aff541059ba2c8a010dba49a
Autor:
Sara Bjursten, Zhiyuan Zhao, Hifaa Al Remawi, Marie Studahl, Ankur Pandita, Joel Simrén, Henrik Zetterberg, Anna-Carin Lundell, Anna Rudin, Lars Ny, Max Levin
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104955- (2024)
Summary: Background: Cancer treatment with immune checkpoint inhibition (ICI) can cause immune-related adverse events in the central nervous system (CNS irAE). There are no blood biomarkers to detect CNS irAE. We investigated if concentrations of S10
Externí odkaz:
https://doaj.org/article/332878addbdc4ac9a9941e3380030091
Autor:
Joel Simrén, Wagner S. Brum, Nicholas J. Ashton, Andrea L. Benedet, Thomas K. Karikari, Hlin Kvartsberg, Emma Sjons, Firoza Z. Lussier, Mira Chamoun, Jenna Stevenson, Robert Hopewell, Vanessa Pallen, Keqiang Ye, Tharick A. Pascoal, Henrik Zetterberg, Pedro Rosa-Neto, Kaj Blennow
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract Introduction Cerebrospinal fluid (CSF) tau biomarkers are reliable diagnostic markers for Alzheimer’s disease (AD). However, their strong association with amyloid pathology may limit their reliability as specific markers of tau neurofibril
Externí odkaz:
https://doaj.org/article/696a39d2f58b4396bc056504a06b2bf9
Autor:
Przemysław R. Kac, Fernando Gonzalez-Ortiz, Joel Simrén, Nele Dewit, Eugeen Vanmechelen, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Thomas K. Karikari
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract Background Blood phosphorylated tau (p-tau) forms are promising Alzheimer’s disease (AD) biomarkers, but validation in matrices other than ethylenediaminetetraacetic acid (EDTA) plasma is limited. Firstly, we assessed the diagnostic potent
Externí odkaz:
https://doaj.org/article/7211e76069b54cb6a47725c40543144e
Publikováno v:
JSAMS Plus, Vol 2, Iss , Pp 100044- (2023)
Objective: To investigate the relationship between head impact characteristics and the levels of blood biomarkers associated with brain injury, neurofilament light (NfL) and glial fibrillary acidic protein (GFAP). Methods: Four elite amateur Muay Tha
Externí odkaz:
https://doaj.org/article/7f2a1a78fbb54592bba5cd48c6afe18f
Autor:
Nelly Kanberg, Joel Simrén, Arvid Edén, Lars-Magnus Andersson, Staffan Nilsson, Nicholas J. Ashton, Pär-Daniel Sundvall, Bengt Nellgård, Kaj Blennow, Henrik Zetterberg, Magnus Gisslén
Publikováno v:
EBioMedicine, Vol 70, Iss , Pp 103512- (2021)
Background: Neurologic manifestations are well-recognized features of coronavirus disease 2019 (COVID-19). However, the longitudinal association of biomarkers reflecting CNS impact and neurological symptoms is not known. We sought to determine whethe
Externí odkaz:
https://doaj.org/article/320eed863e274be788d05650dc908878
Autor:
Helena Sophia Gleerup, Federica Sanna, Peter Høgh, Joel Simrén, Kaj Blennow, Henrik Zetterberg, Steen Gregers Hasselbalch, Nicholas J. Ashton, Anja Hviid Simonsen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Neurodegeneration and axonal injury result in an increasing release of neurofilament light chain (NfL) into bodily fluids, including cerebrospinal fluid (CSF) and blood. Numerous studies have shown that NfL levels in CSF and blood are increased in ne
Externí odkaz:
https://doaj.org/article/05271137e07149dd984a365b9075b110
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction This study investigated alternative pre‐analytical handling of blood for neurofilament light (NfL) analysis where resources are limited. Method Plasma NfL was measured with single molecule array after alternative blood process
Externí odkaz:
https://doaj.org/article/2442ba7479ae43c2bf076e60bf77685e
Autor:
Nicholas J. Ashton, Marc Suárez‐Calvet, Thomas K. Karikari, Juan Lantero‐Rodriguez, Anniina Snellman, Mathias Sauer, Joel Simrén, Carolina Minguillon, Karine Fauria, Kaj Blennow, Henrik Zetterberg
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction We tested how tube types (ethylenediaminetetraacetic acid [EDTA], serum, lithium heparin [LiHep], and citrate) and freeze–thaw cycles affect levels of blood biomarkers for Alzheimer's disease (AD) pathophysiology, glial activa
Externí odkaz:
https://doaj.org/article/54d943bf6dd24afca676ad008cf3a314
Autor:
Nathan A. Huebschmann, Teemu M. Luoto, Justin E. Karr, Ksenia Berghem, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Joel Simrén, Jussi P. Posti, Jessica M. Gill, Grant L. Iverson
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Objective: Identification and validation of blood-based biomarkers for the diagnosis and prognosis of mild traumatic brain injury (mTBI) is of critical importance. There have been calls for more research on mTBI in older adults. We compared blood-bas
Externí odkaz:
https://doaj.org/article/d2bc2df108474c19ac5a5885d662134c