Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Joel, Selkrig"'
Autor:
Marlène S. Birk, Philipp Walch, Tarik Baykara, Stephanie Sefried, Jan Amelang, Elena Buerova, Ingrid Breuer, Jörg Vervoots, Athanasios Typas, Mikhail M. Savitski, André Mateus, Joel Selkrig
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 4, Pp 151448- (2024)
Intracellular bacterial pathogens hijack the protein machinery of infected host cells to evade their defenses and cultivate a favorable intracellular niche. The intracellular pathogen Salmonella enterica subsp. Typhimurium (STm) achieves this by inje
Externí odkaz:
https://doaj.org/article/74aa1058a6c14eb0a08f763d37816a10
Autor:
Joel Selkrig, Megan Stanifer, André Mateus, Karin Mitosch, Inigo Barrio‐Hernandez, Mandy Rettel, Heeyoung Kim, Carlos G P Voogdt, Philipp Walch, Carmon Kee, Nils Kurzawa, Frank Stein, Clément Potel, Anna Jarzab, Bernhard Kuster, Ralf Bartenschlager, Steeve Boulant, Pedro Beltrao, Athanasios Typas, Mikhail M Savitski
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 2, Pp 1-13 (2021)
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a global threat to human health and has compromised economic stability. In addition to the development of an effective vaccine, it is imperative to understand how SARS
Externí odkaz:
https://doaj.org/article/afece9f0c9684154826067b58f6e27a7
Autor:
Zhi Ying Kho, Mohammad A K Azad, Mei-Ling Han, Yan Zhu, Cheng Huang, Ralf B Schittenhelm, Thomas Naderer, Tony Velkov, Joel Selkrig, Qi Tony Zhou, Jian Li
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010308 (2022)
The opportunistic pathogen Acinetobacter baumannii possesses stress tolerance strategies against host innate immunity and antibiotic killing. However, how the host-pathogen-antibiotic interaction affects the overall molecular regulation of bacterial
Externí odkaz:
https://doaj.org/article/b7f6a58f7eb1451c9eb90b1120261c87
Autor:
David Bradley, Cristina Viéitez, Vinothini Rajeeve, Joel Selkrig, Pedro R. Cutillas, Pedro Beltrao
Publikováno v:
Cell Reports, Vol 34, Iss 2, Pp 108602- (2021)
Summary: Protein kinases lie at the heart of cell-signaling processes and are often mutated in disease. Kinase target recognition at the active site is in part determined by a few amino acids around the phosphoacceptor residue. However, relatively li
Externí odkaz:
https://doaj.org/article/119584de46194da883228f78665c0495
Publikováno v:
mSystems, Vol 5, Iss 2 (2020)
ABSTRACT The molecular architecture and function of the Gram-negative bacterial cell envelope are dictated by protein composition and localization. Proteins that localize to the inner membranes (IM) and outer membranes (OM) of Gram-negative bacteria
Externí odkaz:
https://doaj.org/article/a7818cd051ee4cd7b901a1f4e66dd29d
Autor:
Jacob Bobonis, Karin Mitosch, André Mateus, Nicolai Karcher, George Kritikos, Joel Selkrig, Matylda Zietek, Vivian Monzon, Birgit Pfalz, Sarela Garcia-Santamarina, Marco Galardini, Anna Sueki, Callie Kobayashi, Frank Stein, Alex Bateman, Georg Zeller, Mikhail M. Savitski, Johanna R. Elfenbein, Helene L. Andrews-Polymenis, Athanasios Typas
Publikováno v:
Nature. 609:144-150
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68fb129fb0d7097fab919fe2422c6525
https://doi.org/10.1038/s41586-022-05091-4
https://doi.org/10.1038/s41586-022-05091-4
Autor:
David Ochoa, Mindaugas Jonikas, Robert T Lawrence, Bachir El Debs, Joel Selkrig, Athanasios Typas, Judit Villén, Silvia DM Santos, Pedro Beltrao
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 12, Pp 1-14 (2016)
Abstract The coordinated regulation of protein kinases is a rapid mechanism that integrates diverse cues and swiftly determines appropriate cellular responses. However, our understanding of cellular decision‐making has been limited by the small num
Externí odkaz:
https://doaj.org/article/09d2095df86741d5b9f0ad18fe144ab0
Autor:
Elisabetta Cacace, Vladislav Kim, Michael Knopp, Manuela Tietgen, Amber Brauer-Nikonow, Kemal Inecik, André Mateus, Alessio Milanese, Marita Torrissen Mårli, Karin Mitosch, Joel Selkrig, Ana Rita Brochado, Oscar P. Kuipers, Morten Kjos, Georg Zeller, Mikhail M. Savitski, Stephan Göttig, Wolfgang Huber, Athanasios Typas
Drug combinations present a powerful strategy to tackle antimicrobial resistance, but have not been systematically tested in many bacterial species. Here, we used an automated high-throughput setup to profile ∼ 8000 combinations between 65 antibact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69940cd54719419b5b92db68ebc2407d
https://doi.org/10.1101/2022.12.23.521747
https://doi.org/10.1101/2022.12.23.521747
Autor:
Joel Selkrig, Klemens Rottner, Olivia Steele-Mortimer, Cristina Viéitez, Leigh A. Knodler, Matthias Geyer, David W. Holden, Karoline Scholzen, Mikhail M. Savitski, Clement M. Potel, Keith C. Fernandez, Philipp Walch, Mandy Rettel, Frank Stein, Athanasios Typas
Publikováno v:
Cell host & microbe
United States
Cell Host Microbe
United States
Cell Host Microbe
SummaryIntracellular bacterial pathogens inject effector proteins into host cells to hijack diverse cellular processes and promote their survival and proliferation. To systematically map effector-host protein-protein interactions (PPIs) during infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16df6f934d7f95802992b12a3031d53f
https://hdl.handle.net/10033/622977
https://hdl.handle.net/10033/622977
Autor:
Joel Selkrig, Pedro R. Cutillas, Pedro Beltrao, David Bradley, Vinothini Rajeeve, Cristina Viéitez
Publikováno v:
Cell Reports, 34 (2)
Cell Reports, Vol 34, Iss 2, Pp 108602-(2021)
Cell Reports
Cell Reports, Vol 34, Iss 2, Pp 108602-(2021)
Cell Reports
Summary Protein kinases lie at the heart of cell-signaling processes and are often mutated in disease. Kinase target recognition at the active site is in part determined by a few amino acids around the phosphoacceptor residue. However, relatively lit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d431a4dc0749222add09acbe4ad9fb28