Zobrazeno 1 - 10 of 135 pro vyhledávání: '"Joel, Machado"'
1
Akademický článek
Revisiting the utility of identifying nuclear grooves as unique nuclear changes by an object detector model
Autor: Pedro R. F. Rende, Joel Machado Pires, Kátia Sakimi Nakadaira, Sara Lopes, João Vale, Fabio Hecht, Fabyan E. L. Beltrão, Gabriel J. R. Machado, Edna T. Kimura, Catarina Eloy, Helton E. Ramos
Publikováno v: Journal of Pathology and Translational Medicine, Vol 58, Iss 3, Pp 117-126 (2024)
Background Among other structures, nuclear grooves are vastly found in papillary thyroid carcinoma (PTC). Considering that the application of artificial intelligence in thyroid cytology has potential for diagnostic routine, our goal was to develop a
Externí odkaz: https://doaj.org/article/1b64565651eb446094cde5893181c845
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2
Akademický článek
Acute Kaempferol Stimulation Induces AKT Phosphorylation in HepG2 Cells
Autor: Beatriz Santana-Lima, Lucas Humberto Zimmermann Belaunde, Karine Damaceno de Souza, Matheus Elias Rosa, Jose Eduardo de Carvalho, Joel Machado-Jr, Maria Isabel Cardoso Alonso-Vale, Luciano Caseli, Daniela Gonçales Galasse Rando, Luciana Chagas Caperuto
Publikováno v: Life, Vol 14, Iss 6, p 764 (2024)
Type 2 diabetes mellitus (T2DM) stands as a prevalent global public health issue caused by deficiencies in the action of insulin and/or insulin production. In the liver, insulin plays an important role by inhibiting hepatic glucose production and sti
Externí odkaz: https://doaj.org/article/551f3f0a71e441e0ad23c03d0e8252e7
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3
Akademický článek
Lysicamine Reduces Protein Kinase B (AKT) Activation and Promotes Necrosis in Anaplastic Thyroid Cancer
Autor: Mariana Teixeira Rodrigues, Ana Paula Picaro Michelli, Gustavo Felisola Caso, Paloma Ramos de Oliveira, Dorival Mendes Rodrigues-Junior, Mirian Galliote Morale, Joel Machado Júnior, Karina Ramalho Bortoluci, Rodrigo Esaki Tamura, Tamiris Reissa Cipriano da Silva, Cristiano Raminelli, Eric Chau, Biana Godin, Jamile Calil-Silveira, Ileana G. Sanchez Rubio
Publikováno v: Pharmaceuticals, Vol 16, Iss 12, p 1687 (2023)
Anaplastic thyroid cancer (ATC) is an aggressive form of thyroid cancer (TC), accounting for 50% of total TC-related deaths. Although therapeutic approaches against TC have improved in recent years, the survival rate remains low, and severe adverse e
Externí odkaz: https://doaj.org/article/a71652dc442f4d3a9f88edb218ec1cd7
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6
Akademický článek
Increased bone resorption by long-term cigarette smoke exposure in animal model
Autor: Jader Joel Machado Junqueira, Juliana Dias Lourenço, Kaique Rodrigues da Silva, Vanda Jorgetti, Rodolfo P. Vieira, Amanda Aparecida de Araujo, Kátia De Angelis, Aristides Tadeu Correia, Luan Henrique Vasconcelos Alves, Iolanda de Fátima Lopes Calvo Tibério, Alexandre Póvoa Barbosa, Fernanda Degobbi Tenorio Quirino dos Santos Lopes
Publikováno v: Heliyon, Vol 7, Iss 12, Pp e08587- (2021)
Introduction: Clinical and experimental studies have been attesting the deleterious effects of smoking mainly due to the stimulation of osteoclastogenesis and inhibition of osteoblastogenesis. However the physiological mechanisms that can explain the
Externí odkaz: https://doaj.org/article/5fa92613752b4531932c4a2c6755c912
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7
Akademický článek
The regulation of the sulfur amino acid biosynthetic pathway in Cryptococcus neoformans: the relationship of Cys3, Calcineurin, and Gpp2 phosphatases
Autor: Amanda Teixeira de Melo, Kevin Felipe Martho, Thiago Nunes Roberto, Erika S. Nishiduka, Joel Machado, Otávio J. B. Brustolini, Alexandre K. Tashima, Ana Tereza Vasconcelos, Marcelo A. Vallim, Renata C. Pascon
Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-19 (2019)
Abstract Cryptococcosis is a fungal disease caused by C. neoformans. To adapt and survive in diverse ecological niches, including the animal host, this opportunistic pathogen relies on its ability to uptake nutrients, such as carbon, nitrogen, iron,
Externí odkaz: https://doaj.org/article/116a79f3ffc64b138ed3ac4a44ce993d
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