Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Joeeta Chowdhury"'
Autor:
Laila Ritsma, Ipsita Dey-Guha, Nilesh Talele, Xavier Sole, Salony, Joeeta Chowdhury, Kenneth N Ross, Sridhar Ramaswamy
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175300 (2017)
TGF-β is a cytokine thought to function as a tumor promoter in advanced malignancies. In this setting, TGF-β increases cancer cell proliferation, survival, and migration, and orchestrates complex, pro-tumorigenic changes in the tumor microenvironme
Externí odkaz:
https://doaj.org/article/928f5505a3db4d31bd3f4df0c416ec6c
Autor:
Sridhar Ramaswamy, Kenneth N. Ross, Hege G. Russnes, Anne-Lise Borresen-Dale, Dennis Sgroi, Massimo Loda, Mari Mino-Kenudson, Joeeta Chowdhury, Xavier Solé, Nilesh P. Talele, Albert C. Yeh, Sheheryar Kabraji, Ipsita Dey-Guha, Cleidson P. Alves
Supp. Fig. 2. AKT1-WT versus AKT1-E17K: Functional assays in vitro (Part 1). Proliferation assays performed three days after induction of AKT1-WT or AKT1-E17K protein under normal fetal bovine serum (10%), low serum (1%), hypoxia (4% O2), and with pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11947d0f73d9860a6894097037c7d2b6
https://doi.org/10.1158/1535-7163.22504653.v1
https://doi.org/10.1158/1535-7163.22504653.v1
Autor:
Sridhar Ramaswamy, Kenneth N. Ross, Hege G. Russnes, Anne-Lise Borresen-Dale, Dennis Sgroi, Massimo Loda, Mari Mino-Kenudson, Joeeta Chowdhury, Xavier Solé, Nilesh P. Talele, Albert C. Yeh, Sheheryar Kabraji, Ipsita Dey-Guha, Cleidson P. Alves
Supp. Fig. 3. AKT1-WT versus AKT1-E17K: Functional assays in vitro (Part 2). Bar plots for functional assays performed three days after induction of AKT1-WT or AKT1-E17K protein for colony formation (on plastic), migration, invasion (in matrigel), co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b06e77c4de0fdc30169524ff9b62cf
https://doi.org/10.1158/1535-7163.22504647.v1
https://doi.org/10.1158/1535-7163.22504647.v1
Autor:
Sridhar Ramaswamy, Shobha Vasudevan, Wilhelm Haas, Kenneth N. Ross, Joeeta Chowdhury, Ju H. Lee, Myriam Boukhali, Laila Ritsma, Ipsita Dey-Guha, Cleidson P. Alves, Xavier Solé
Bioactivity and effect of microvesicles on growth rate using MK-2206 inhibitor in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1346add81c3795195f1a63c9222ff762
https://doi.org/10.1158/1535-7163.22504069
https://doi.org/10.1158/1535-7163.22504069
Autor:
Sridhar Ramaswamy, Kenneth N. Ross, Hege G. Russnes, Anne-Lise Borresen-Dale, Dennis Sgroi, Massimo Loda, Mari Mino-Kenudson, Joeeta Chowdhury, Xavier Solé, Nilesh P. Talele, Albert C. Yeh, Sheheryar Kabraji, Ipsita Dey-Guha, Cleidson P. Alves
Analysis of correlation between the presence of AKT1-E17K mutation and clinical aspects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405f9371f5f306cb771572c77c6f4aae
https://doi.org/10.1158/1535-7163.22504638
https://doi.org/10.1158/1535-7163.22504638
Autor:
Sridhar Ramaswamy, Kenneth N. Ross, Hege G. Russnes, Anne-Lise Borresen-Dale, Dennis Sgroi, Massimo Loda, Mari Mino-Kenudson, Joeeta Chowdhury, Xavier Solé, Nilesh P. Talele, Albert C. Yeh, Sheheryar Kabraji, Ipsita Dey-Guha, Cleidson P. Alves
Supp. Fig. 5. Sensitivity to Paclitaxel in AKT1-WT, AKT1-E17K xenographic tumors. Mice with subcutaneous (A) AKT1-WT or (B) AKT-E17K tumors were treated with paclitaxel. The ratio of treated and non-treated is shown in C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa1a682f89df17fd06c8774a79e61e4
https://doi.org/10.1158/1535-7163.22504641.v1
https://doi.org/10.1158/1535-7163.22504641.v1
Autor:
Sridhar Ramaswamy, Kenneth N. Ross, Hege G. Russnes, Anne-Lise Borresen-Dale, Dennis Sgroi, Massimo Loda, Mari Mino-Kenudson, Joeeta Chowdhury, Xavier Solé, Nilesh P. Talele, Albert C. Yeh, Sheheryar Kabraji, Ipsita Dey-Guha, Cleidson P. Alves
Supp. Fig. 4. Senescent cells in tumors. Number of senescent cells (β-Gal+ cells) in different xenograft models. Error bars indicate mean {plus minus} SEM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27745938164e24814cf8e1ff9da08a4f
https://doi.org/10.1158/1535-7163.22504644.v1
https://doi.org/10.1158/1535-7163.22504644.v1
Autor:
Sridhar Ramaswamy, Kenneth N. Ross, Hege G. Russnes, Anne-Lise Borresen-Dale, Dennis Sgroi, Massimo Loda, Mari Mino-Kenudson, Joeeta Chowdhury, Xavier Solé, Nilesh P. Talele, Albert C. Yeh, Sheheryar Kabraji, Ipsita Dey-Guha, Cleidson P. Alves
Supp. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddf6d3c3992598c19ea98f3a5ec41ed
https://doi.org/10.1158/1535-7163.22504662
https://doi.org/10.1158/1535-7163.22504662
Autor:
Sridhar Ramaswamy, Kenneth N. Ross, Hege G. Russnes, Anne-Lise Borresen-Dale, Dennis Sgroi, Massimo Loda, Mari Mino-Kenudson, Joeeta Chowdhury, Xavier Solé, Nilesh P. Talele, Albert C. Yeh, Sheheryar Kabraji, Ipsita Dey-Guha, Cleidson P. Alves
Supp. Fig. 1. AKT1-WT, AKT1-E17K, and downstream signaling. Immunoblots using indicated anibodies of lysates from cancer cell three days after induction of AKT1-WT or AKT1-E17K protein.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6388cb09a7faf3550d68a5720ca72af6
https://doi.org/10.1158/1535-7163.22504656
https://doi.org/10.1158/1535-7163.22504656
Autor:
Sridhar Ramaswamy, Shobha Vasudevan, Wilhelm Haas, Kenneth N. Ross, Joeeta Chowdhury, Ju H. Lee, Myriam Boukhali, Laila Ritsma, Ipsita Dey-Guha, Cleidson P. Alves, Xavier Solé
Small molecule inhibitors of AKT (v-akt murine thymoma viral oncogene homolog) signaling are being evaluated in patients with various cancer types, but have so far proven therapeutically disappointing for reasons that remain unclear. Here, we treat c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd275fd82a6b4004fd4f6ddf79e2b86
https://doi.org/10.1158/1535-7163.c.6537610.v1
https://doi.org/10.1158/1535-7163.c.6537610.v1