Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Joe-Marc Chauvin"'
Autor:
Ornella Pagliano, Robert M. Morrison, Joe-Marc Chauvin, Hridesh Banerjee, Diwakar Davar, Quanquan Ding, Tokiyoshi Tanegashima, Wentao Gao, Saranya R. Chakka, Richelle DeBlasio, Ava Lowin, Kevin Kara, Mignane Ka, Bochra Zidi, Rada Amin, Itay Raphael, Shuowen Zhang, Simon C. Watkins, Cindy Sander, John M. Kirkwood, Marcus Bosenberg, Ana C. Anderson, Vijay K. Kuchroo, Lawrence P. Kane, Alan J. Korman, Arvind Rajpal, Sean M. West, Minhua Han, Christine Bee, Xiaodi Deng, Xiao Min Schebye, Pavel Strop, Hassane M. Zarour
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 9 (2022)
T cell immunoglobulin mucin domain-containing protein 3 (Tim-3) negatively regulates innate and adaptive immunity in cancer. To identify the mechanisms of Tim-3 in cancer immunity, we evaluated the effects of Tim-3 blockade in human and mouse melanom
Externí odkaz:
https://doaj.org/article/00341078d5a94f57ba93043742d00efb
Autor:
Hassane Zarour, John Kirkwood, Joe-Marc Chauvin, Arivarasan Karunamurthy, Douglas Hartman, Richelle DeBlasio, Quanquan Ding, Ornella Pagliano, Amy Rose
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/23cceed6d50e4d5b9102fa53543f2387
Autor:
Joe-Marc Chauvin, Hassane M Zarour
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Tumors evade immune-mediated recognition through multiple mechanisms of immune escape. On chronic tumor antigen exposure, T cells become dysfunctional/exhausted and upregulate various checkpoint inhibitory receptors (IRs) that limit T cells’ surviv
Externí odkaz:
https://doaj.org/article/cba7c825e8bf48f9b194fb8702badd50
Autor:
Guillaume Sarrabayrouse, Céline Bossard, Joe-Marc Chauvin, Anne Jarry, Guillaume Meurette, Elodie Quévrain, Chantal Bridonneau, Laurence Preisser, Karim Asehnoune, Nathalie Labarrière, Frédéric Altare, Harry Sokol, Francine Jotereau
Publikováno v:
PLoS Biology, Vol 12, Iss 4, p e1001833 (2014)
How the microbiota affects health and disease is a crucial question. In mice, gut Clostridium bacteria are potent inducers of colonic interleukin (IL)-10-producing Foxp3 regulatory T cells (Treg), which play key roles in the prevention of colitis and
Externí odkaz:
https://doaj.org/article/9c8384521d34434aa5d7daca284ee34d
Autor:
Saumendra N. Sarkar, Greg M. Delgoffe, Christopher J. Bakkenist, Hassane M. Zarour, Veit Hornung, Stephen H. Thorne, Pooja Karukonda, Joe-Marc Chauvin, Yiyang Wang, Ashley V. Menk, Chandra Nath Roy, Rashmi Srivastava, Frank P. Vendetti, Nicole E. Scharping, Weizhou Hou, Lulu Shao
Multiple studies have associated the transcription factor IRF1 with tumor-suppressive activities. Here, we report an opposite tumor cell–intrinsic function of IRF1 in promoting tumor growth. IRF1-deficient tumor cells showed reduced tumor growth in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a56b6cc559cb7e26d9a33e1e0d6618a
https://doi.org/10.1158/2326-6066.c.6549892
https://doi.org/10.1158/2326-6066.c.6549892
Autor:
Saumendra N. Sarkar, Greg M. Delgoffe, Christopher J. Bakkenist, Hassane M. Zarour, Veit Hornung, Stephen H. Thorne, Pooja Karukonda, Joe-Marc Chauvin, Yiyang Wang, Ashley V. Menk, Chandra Nath Roy, Rashmi Srivastava, Frank P. Vendetti, Nicole E. Scharping, Weizhou Hou, Lulu Shao
Supplementary Figure S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a707a925bb3118d4a3df3e9885566d1c
https://doi.org/10.1158/2326-6066.22542367
https://doi.org/10.1158/2326-6066.22542367
Autor:
Saumendra N. Sarkar, Greg M. Delgoffe, Christopher J. Bakkenist, Hassane M. Zarour, Veit Hornung, Stephen H. Thorne, Pooja Karukonda, Joe-Marc Chauvin, Yiyang Wang, Ashley V. Menk, Chandra Nath Roy, Rashmi Srivastava, Frank P. Vendetti, Nicole E. Scharping, Weizhou Hou, Lulu Shao
Supplementary Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d77854966602f0497b01ef55305dcd
https://doi.org/10.1158/2326-6066.22542358
https://doi.org/10.1158/2326-6066.22542358
Autor:
Hassane M. Zarour, Mark J. Smyth, Alan J. Korman, Robert J. Johnston, John M. Kirkwood, Diwakar Davar, Soldano Ferrone, Xian-Yang Li, Jiajie Hou, Cindy Sanders, Richelle DeBlasio, Quanquan Ding, Carmine Menna, Ornella Pagliano, Mignane Ka, Joe-Marc Chauvin
Purpose:Natural killer (NK) cells play a critical role in tumor immunosurveillance. Multiple activating and inhibitory receptors (IR) regulate NK-cell–mediated tumor control. The IR T-cell immunoglobulin and ITIM domain (TIGIT) and its counter-rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3868ce46eb0c84b21578b0324b54b3e
https://doi.org/10.1158/1078-0432.c.6529316.v1
https://doi.org/10.1158/1078-0432.c.6529316.v1
Autor:
Hassane M. Zarour, Mark J. Smyth, Alan J. Korman, Robert J. Johnston, John M. Kirkwood, Diwakar Davar, Soldano Ferrone, Xian-Yang Li, Jiajie Hou, Cindy Sanders, Richelle DeBlasio, Quanquan Ding, Carmine Menna, Ornella Pagliano, Mignane Ka, Joe-Marc Chauvin
Supplemental Figure 2. CD155 expression in melanoma cells inversely correlates with the TIGIT/CD226 expression ratio in TiNKs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee8212e5728ae8a06bead24ea34fea5
https://doi.org/10.1158/1078-0432.22476167
https://doi.org/10.1158/1078-0432.22476167
Autor:
Hassane M. Zarour, John M. Kirkwood, Cindy Sander, Joe-Marc Chauvin, Ornella Pagliano, Julien Fourcade, Zhaojun Sun
Immune checkpoint inhibitors show great promise as therapy for advanced melanoma, heightening the need to determine the most effective use of these agents. Here, we report that programmed death-1high (PD-1high) tumor antigen (TA)–specific CD8+ T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28cbe2030cad8cd4f2b09d7994d30083
https://doi.org/10.1158/0008-5472.c.6507357
https://doi.org/10.1158/0008-5472.c.6507357