Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Joe X. Zhou"'
Autor:
Runhua Feng, Yuling Wang, Vijaya Ramachandran, Qinhong Ma, Matthew M. May, Ming Li, Joe X. Zhou, Xiang Xu, Kejing Xu, Shenying Fang, Weiya Xia, Dawen Sui, Huey Liu, Xiaolian Gao, Victor Prieto, Stephen C. Blacklow, Mason Lu, Jeffrey E. Lee
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-13 (2020)
Abstract Background MUC18 is a glycoprotein highly expressed on the surface of melanoma and other cancers which promotes tumor progression and metastasis. However, its mechanism of action and suitability as a therapeutic target are unknown. Methods A
Externí odkaz:
https://doaj.org/article/80d24a3f91c041759c509a8cef74a39f
Autor:
Yan Wu, Weihong Nian, Jing Xiao, Mengjun Shu, Hongbin Yan, Qing Zhou, Hongli Wei, Zhuzi He, Zhaohua Chi, Joe X. Zhou, Chuanying Xu
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
HER2 overexpression is frequently associated with tumor metastasis and poor prognosis of breast cancer. More evidence indicates that HER3 is involved in HER2-resistant therapies. Combination treatments with two or more different monoclonal antibodies
Publikováno v:
Process Scale Purification of Antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8008136ec9867c87eaff5857dd98d32
https://doi.org/10.1002/9781119126942.ch23
https://doi.org/10.1002/9781119126942.ch23
Publikováno v:
Medicine & Science in Sports & Exercise. 51:556-556
Autor:
Jinshu Qiu, Neil Bingham, Bryan Dransart, Helena Yeung, Ge Jiang, Manpreet-Vick S. Wadhwa, Tim Tressel, Chengfeng Zhou, Joe X. Zhou
Publikováno v:
Journal of Membrane Science. 325:735-741
An issue identified during filtration of mAb drug substance is Polysorbate-20 absorption by polyethersulfone filter membranes. Experiments determined that both polyvinylidene fluoride filter membranes and polyethersulfone filter membranes bind Polyso
Publikováno v:
Biotechnology and Bioengineering. 100:488-496
Once highly selective protein A affinity is chosen for robust mAb downstream processing, the major role of polishing steps is to remove product related impurities, trace amounts of host cell proteins, DNA/RNA, and potential viral contaminants. Dispos
Autor:
Joe X. Zhou, Solamo Felix M, Tim Tressel, Rosalind Stenson, Sam Guhan, Shinta Dermawan, Greg Flynn
Publikováno v:
Journal of Chromatography A. 1175:69-80
The commercial production of recombinant human monoclonal antibody therapeutics demands robust processes. In this article we describe the development of a pH-conductivity hybrid gradient for a cation-exchange chromatography step to obtain high bindin
Autor:
Joe X. Zhou, Solamo Felix M, Oscar Reif, Tim Tressel, Jeff Mora, Tony Hong, Uwe Gottschalk, Fred Hutchison, Andre Pastor, Michael Murphy, Shinta Dermawan
Publikováno v:
Journal of Chromatography A. 1134:66-73
Process-scale antibody production requires polishing steps with extremely high product throughput and robust operation. In this communication, the Sartobind Q membrane adsorber for process-scale antibody production is evaluated as an alternative to Q
Autor:
Joe X. Zhou, Tim Tressel
Publikováno v:
Biotechnology Progress. 22:341-349
The large-scale production of recombinant human monoclonal antibodies demands economical purification processes with high throughputs. In this article we briefly describe a common antibody process and evaluate the Q membrane adsorber for process-scal
Publikováno v:
Microelectronic Engineering. :409-414
MBE growth on patterned substrate has been studied by means of transmission electron microscopy (TEM). The surface morphology development during the initial stage of epitaxial growth and the lateral epilayer thickness variation have been studied on a