Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Joe V Chakkalakal"'
Autor:
Jacqueline A Larouche, Mahir Mohiuddin, Jeongmoon J Choi, Peter J Ulintz, Paula Fraczek, Kaitlyn Sabin, Sethuramasundaram Pitchiaya, Sarah J Kurpiers, Jesus Castor-Macias, Wenxuan Liu, Robert Louis Hastings, Lemuel A Brown, James F Markworth, Kanishka De Silva, Benjamin Levi, Sofia D Merajver, Gregorio Valdez, Joe V Chakkalakal, Young C Jang, Susan V Brooks, Carlos A Aguilar
Publikováno v:
eLife, Vol 10 (2021)
During aging and neuromuscular diseases, there is a progressive loss of skeletal muscle volume and function impacting mobility and quality of life. Muscle loss is often associated with denervation and a loss of resident muscle stem cells (satellite c
Externí odkaz:
https://doaj.org/article/1102e70e73174fe0b033c99e67010a4a
Autor:
Wenxuan Liu, Alanna Klose, Sophie Forman, Nicole D Paris, Lan Wei-LaPierre, Mariela Cortés-Lopéz, Aidi Tan, Morgan Flaherty, Pedro Miura, Robert T Dirksen, Joe V Chakkalakal
Publikováno v:
eLife, Vol 6 (2017)
Neuromuscular junction degeneration is a prominent aspect of sarcopenia, the age-associated loss of skeletal muscle integrity. Previously, we showed that muscle stem cells activate and contribute to mouse neuromuscular junction regeneration in respon
Externí odkaz:
https://doaj.org/article/378451325042469199ba48d1d765b206
Publikováno v:
eLife, Vol 5 (2016)
Skeletal muscle regenerative potential declines with age, in part due to deficiencies in resident stem cells (satellite cells, SCs) and derived myogenic progenitors (MPs); however, the factors responsible for this decline remain obscure. TGFβ superf
Externí odkaz:
https://doaj.org/article/747aab7c4df94584a33aa0bbf1e74553
Publikováno v:
eLife, Vol 4 (2015)
Skeletal muscle maintenance depends on motor innervation at neuromuscular junctions (NMJs). Multiple mechanisms contribute to NMJ repair and maintenance; however muscle stem cells (satellite cells, SCs), are deemed to have little impact on these proc
Externí odkaz:
https://doaj.org/article/f8cf9b2fb9f048079c02b9861506a7ac
Autor:
Thomas N. O’Connor, Jacob G. Kallenbach, Haley M. Orciuoli, Nicole D. Paris, John F. Bachman, Carl J. Johnston, Eric Hernady, Jacqueline P. Williams, Robert T. Dirksen, Joe V. Chakkalakal
Publikováno v:
Skeletal Muscle, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Background Radiotherapy is commonly used to treat childhood cancers and can have adverse effects on muscle function, but the underlying mechanisms have yet to be fully elucidated. We hypothesized that endurance exercise following radiation t
Externí odkaz:
https://doaj.org/article/ecc26d38809d447f86a80307ebda6bc4
Autor:
Jacob G. Kallenbach, John F. Bachman, Nicole D. Paris, Roméo S. Blanc, Thomas O'Connor, Esraa Furati, Eric Hernady, Carl J. Johnston, Jacqueline P. Williams, Joe V. Chakkalakal
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 1, Pp 296-310 (2022)
Abstract Background As paediatric cancer survivors are living into adulthood, they suffer from the age‐related, accelerated decline of functional skeletal muscle tissue, termed sarcopenia. With ionizing radiation (radiotherapy) at the core of paedi
Externí odkaz:
https://doaj.org/article/65609b7e38e04fbdb3872959e7da9f5f
Autor:
Calvin L. Cole, John F. Bachman, Jian Ye, Joseph Murphy, Scott A. Gerber, Christopher A. Beck, Brendan F. Boyce, Gowrishankar Muthukrishnan, Joe V. Chakkalakal, Edward M. Schwarz, David Linehan
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 3, Pp 731-745 (2021)
Abstract Background Skeletal muscle wasting (SMW) in cancer patients is associated with increased morbidity, mortality, treatment intolerance and discontinuation, and poor quality of life. This is particularly true for patients with pancreatic ductal
Externí odkaz:
https://doaj.org/article/253d934b0fa14eca9e41eee1ebbe2db1
Autor:
Roméo S. Blanc, Jacob G. Kallenbach, John F. Bachman, Amanda Mitchell, Nicole D. Paris, Joe V. Chakkalakal
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Chronic inflammation is a feature of age-related regenerative decline in skeletal muscles, but how it directly affects resident muscle stem cell fate and function is unclear. Here, the authors show that Ccr2 signaling in muscle stem cell derived prog
Externí odkaz:
https://doaj.org/article/97820830ea5346b191e5ed3b4140df98
Autor:
John F. Bachman, Roméo S. Blanc, Nicole D. Paris, Jacob G. Kallenbach, Carl J. Johnston, Eric Hernady, Jacqueline P. Williams, Joe V. Chakkalakal
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101760- (2020)
Summary: During prepubertal development, muscle stem cells (satellite cells, SCs) actively contribute to myofiber growth. Because some SCs are active during this time, they may be particularly susceptible to damage. Using a Small Animal Radiation Res
Externí odkaz:
https://doaj.org/article/0a4a59ac0133476d9c53eb22c887a706
Autor:
Joe V. Chakkalakal, Jian Ye, John F. Bachman, Joseph D Murphy, Edward M. Schwarz, Scott A. Gerber, Christopher A. Beck, Brendan F. Boyce, Calvin L. Cole, Gowrishankar Muthukrishnan, David C. Linehan
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 3, Pp 731-745 (2021)
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle
Background Skeletal muscle wasting (SMW) in cancer patients is associated with increased morbidity, mortality, treatment intolerance and discontinuation, and poor quality of life. This is particularly true for patients with pancreatic ductal adenocar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555b782cb371410c836463c147b5d8bc
https://doaj.org/article/253d934b0fa14eca9e41eee1ebbe2db1
https://doaj.org/article/253d934b0fa14eca9e41eee1ebbe2db1