Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Joe Sarkis"'
Autor:
Bijina Balakrishnan, Xinhua Yan, Marshall D. McCue, Olivia Bellagamba, Aaron Guo, Felicity Winkler, Jason Thall, Lisa Crawford, Rain Dimen, Sara Chen, Sean McEnaney, Yiman Wu, Mike Zimmer, Joe Sarkis, Paolo G.V. Martini, Patrick F. Finn, Kent Lai
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101191- (2024)
Despite the implementation of lifesaving newborn screening programs and a galactose-restricted diet, many patients with classic galactosemia develop long-term debilitating neurological deficits and primary ovarian insufficiency. Previously, we showed
Externí odkaz:
https://doaj.org/article/d2fda7725fe9434a86e2d785a3e6d368
Autor:
Jingsong Cao, Minjung Choi, Eleonora Guadagnin, Maud Soty, Marine Silva, Vincent Verzieux, Edward Weisser, Arianna Markel, Jenny Zhuo, Shi Liang, Ling Yin, Andrea Frassetto, Anne-Renee Graham, Kristine Burke, Tatiana Ketova, Cosmin Mihai, Zach Zalinger, Becca Levy, Gilles Besin, Meredith Wolfrom, Barbara Tran, Christopher Tunkey, Erik Owen, Joe Sarkis, Athanasios Dousis, Vladimir Presnyak, Christopher Pepin, Wei Zheng, Lei Ci, Marjie Hard, Edward Miracco, Lisa Rice, Vi Nguyen, Mike Zimmer, Uma Rajarajacholan, Patrick F. Finn, Gilles Mithieux, Fabienne Rajas, Paolo G. V. Martini, Paloma H. Giangrande
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Glycogen Storage Disease 1a (Gsd1a) is an inherited disorder caused by glucose 6-phosphatase (G6Pase-α) deficiency and characterized by hypoglycaemia and high risk of liver cancer. Here the authors develop a mRNA-based G6Pase-α delivery therapy tha
Externí odkaz:
https://doaj.org/article/977236f43e9f4fb4a8b6a0322537f1cb
Autor:
Joe Sarkis, Véronique Vié
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Biological membranes are highly dynamic in their ability to orchestrate vital mechanisms including cellular protection, organelle compartmentalization, cellular biomechanics, nutrient transport, molecular/enzymatic recognition, and membrane fusion. C
Externí odkaz:
https://doaj.org/article/6a7bb743e4c94d56bfa3b1e63a1d36ca
Protein-lipid interactions constitute a very important class of biological interactions critical for multiple cell and tissue functions. It is believed that most lipid-protein interactions are very weak, with affinities in the 1mM-1μM range. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc84d7c063339f77387ac8581c1ed03d
https://doi.org/10.1101/2022.08.22.504198
https://doi.org/10.1101/2022.08.22.504198
Autor:
Christopher Tunkey, Minjung Choi, Wei Zheng, Gilles Besin, Lisa M. Rice, Andrea Frassetto, Athanasios Dousis, Edward J. Miracco, Uma Rajarajacholan, Erik Owen, Patrick Finn, Fabienne Rajas, Eleonora Guadagnin, Kristin E. Burke, Mike Zimmer, Vincent Verzieux, Christopher Pepin, Cosmin Mihai, meredith##Wolfrom, Maud Soty, Becca Levy, Joe Sarkis, Zach Zalinger, Barbara Tran, Marine Silva, Arianna Markel, Ling Yin, Paloma H. Giangrande, Vi Nguyen, Jingsong Cao, Marjie Hard, Paolo Martini, Gilles Mithieux, Jenny Zhuo, Shi Liang, Edward Weisser, Vladimir Presnyak, Anne-Renee##Graham, Tatiana Ketova, Lei Ci
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.3090. ⟨10.1038/s41467-021-23318-2⟩
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.3090. ⟨10.1038/s41467-021-23318-2⟩
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Glycogen Storage Disease 1a (GSD1a) is a rare, inherited metabolic disorder caused by deficiency of glucose 6-phosphatase (G6Pase-α). G6Pase-α is critical for maintaining interprandial euglycemia. GSD1a patients exhibit life-threatening hypoglycemi
Autor:
Véronique Vié, Joe Sarkis
Publikováno v:
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology, 2020, 8, ⟨10.3389/fbioe.2020.00270⟩
Frontiers in Bioengineering and Biotechnology, Frontiers, 2020, 8, ⟨10.3389/fbioe.2020.00270⟩
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Frontiers in Bioengineering and Biotechnology, 2020, 8, ⟨10.3389/fbioe.2020.00270⟩
Frontiers in Bioengineering and Biotechnology, Frontiers, 2020, 8, ⟨10.3389/fbioe.2020.00270⟩
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
International audience; Biological membranes are highly dynamic in their ability to orchestrate vital mechanisms including cellular protection, organelle compartmentalization, cellular biomechanics, nutrient transport, molecular/enzymatic recognition
Autor:
Jie Zhao, Olivier Marcillat, Thierry Granjon, Yi Jia, Loïc J. Blum, Joe Sarkis, Agnès Girard-Egrot, Junbai Li, Ofelia Maniti, Samuel Rebaud
Publikováno v:
Journal of Liposome Research
Journal of Liposome Research, Informa Healthcare, 2014, 25 (2), pp.122-130
Journal of Liposome Research, Informa Healthcare, 2014, 25 (2), pp.122-130
International audience; Conventional liposomes have a short life-time in blood, unless they are protected by a polymer envelope, most often polyethylene glycol. However, these stabilizing polymers frequently interfere with cellular uptake, impede lip
Autor:
Magali Audry, Christelle Breton, Agnès Girard-Egrot, Joana Rocha, Joe Sarkis, Monica M. Palcic, Maryse A. Block, Laurence Pitou, Daniele de Sanctis, J. Radzimanowski, Valérie Chazalet, Eric Maréchal, Aline Thomas
Publikováno v:
Plant Journal
Plant Journal, Wiley, 2016, 85 (5), pp.622-633. ⟨10.1111/tpj.13129⟩
Plant Journal, 2016, 85 (5), pp.622-633. ⟨10.1111/tpj.13129⟩
Plant Journal, Wiley, 2016, 85 (5), pp.622-633. ⟨10.1111/tpj.13129⟩
Plant Journal, 2016, 85 (5), pp.622-633. ⟨10.1111/tpj.13129⟩
International audience; Monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG) are the major lipid components of photosynthetic membranes, and hence the most abundant lipids in the biosphere. They are essential for assembly and fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7836c0100b169f82f92e60e99cba3ac
https://hal.archives-ouvertes.fr/hal-01272198
https://hal.archives-ouvertes.fr/hal-01272198
Autor:
Véronique Vié, Ofelia Maniti, Maryse A. Block, Joana Rocha, Juliette Jouhet, Agnès Girard-Egrot, Christelle Breton, Joe Sarkis, Eric Maréchal
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2014, 28, pp.3114-3123. ⟨10.1096/fj.14-250415⟩
FASEB Journal, 2014, 28 (7), pp.3114-3123. ⟨10.1096/fj.14-250415⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2014, 28 (7), pp.3114-3123. ⟨10.1096/fj.14-250415⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2014, 28, pp.3114-3123. ⟨10.1096/fj.14-250415⟩
FASEB Journal, 2014, 28 (7), pp.3114-3123. ⟨10.1096/fj.14-250415⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2014, 28 (7), pp.3114-3123. ⟨10.1096/fj.14-250415⟩
International audience; : Mono- and digalactosyldiacylglycerol (MGDG and DGDG) are the most abundant lipids of photosynthetic membranes (thylakoids). In Arabidopsis green tissues, MGD1 is the main enzyme synthesizing MGDG. This monotopic enzyme is em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345ecf00b5e57ec545373082e80b8ca4
https://hal.archives-ouvertes.fr/hal-00987212
https://hal.archives-ouvertes.fr/hal-00987212
Autor:
Anne Simon, Lyndel Mason, Samuel Rebaud, Loïc J. Blum, Agnès Girard-Egrot, Andreas Hofmann, Conan K. Wang, Joe Sarkis
Publikováno v:
BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2014, 1838 (10), pp.2698-2707
BBA-Biochimica et Biophysica Acta, Elsevier, 2014, 1838 (10), pp.2698-2707
International audience; VIsinin-LIke Proteins (VILIPs) are a subfamily of the Neuronal Calcium Sensor (NCS) proteins, which possess both N-myristoylation and EF-hand motifs allowing for a putative 'calcium-myristoyl switch' regulation mechanism. It h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da1b7aa79bc0fb800de4ecba9644f58
https://hal.archives-ouvertes.fr/hal-01145287
https://hal.archives-ouvertes.fr/hal-01145287