Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Joe Salvino"'
Autor:
Ashoke Bhattacharjee, Joel Adam Goldberg, Roger Hanselmann, Rongliang Lou, Shili Chen, Ayomi Oyelere, Jennifer Tran, Joseph A. Ippolito, Alia Orbin, Deping Wang, Dane M. Springer, Jiacheng Zhou, Yusheng Wu, Yi Chen, Graham Johnson, Jay J. Farmer, Erin M. Duffy, Joe Salvino
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:6179-6183
From the X-ray crystal structures of linezolid and the non-selective antibiotic sparsomycin, we have derived a new family of hybrid oxazolidinones. From this initial compound set we have developed a new biaryloxazolidinone scaffold that shows both po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95dc944e04f041513ace225e303d463d
https://doi.org/10.1016/j.bmcl.2008.10.014
https://doi.org/10.1016/j.bmcl.2008.10.014
Autor:
Joe Salvino, Shili Chen, Ayomi Oyelere, Joseph A. Ippolito, Jay J. Farmer, Yi Chen, Jiacheng Zhou, Rongliang Lou, Yusheng Wu, Deping Wang, Graham Johnson, Joel Adam Goldberg, Roger Hanselmann, Erin M. Duffy, Ashoke Bhattacharjee, Jennifer Tran, Alia Orbin, Dane M. Springer
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(23)
We have developed a first generation of hybrid sparsomycin–linezolid compounds into a new family of orally bioavailable biaryloxazolidinones that have activity against both linezolid-susceptible and -resistant Gram-positive bacteria as well as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c587030f92531ac7d79899636f3c9e
https://pubmed.ncbi.nlm.nih.gov/18947996
https://pubmed.ncbi.nlm.nih.gov/18947996