Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Joe S. Mymryk"'
Autor:
Benedek Dankó, Julia Hess, Kristian Unger, Daniel Samaga, Christoph Walz, Axel Walch, Na Sun, Philipp Baumeister, Peter Y. F. Zeng, Franziska Walter, Sebastian Marschner, Richard Späth, Olivier Gires, Timm Herkommer, Ramin Dazeh, Thaina Matos, Lisa Kreutzer, Johann Matschke, Katharina Eul, Frederick Klauschen, Ulrike Pflugradt, Martin Canis, Ute Ganswindt, Joe S. Mymryk, Barbara Wollenberg, Anthony C. Nichols, Claus Belka, Horst Zitzelsberger, Kirsten Lauber, Martin Selmansberger
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-20 (2024)
Abstract Head and Neck Squamous Cell Carcinoma (HNSCC) is a heterogeneous malignancy that remains a significant challenge in clinical management due to frequent treatment failures and pronounced therapy resistance. While metabolic dysregulation appea
Externí odkaz:
https://doaj.org/article/478152ef0db84845b323352406d212bd
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Epstein-Barr virus (EBV) is a pathogen known to cause a number of malignancies, often taking years for them to develop after primary infection. EBV-associated gastric cancer (EBVaGC) is one such malignancy, and is an immunologically, molecularly and
Externí odkaz:
https://doaj.org/article/8786081066544b77a4ea860e5ebaab76
Autor:
Peter Y.F. Zeng, Stephenie D. Prokopec, Stephen Y. Lai, Nicole Pinto, Michelle A. Chan-Seng-Yue, Roderick Clifton-Bligh, Michelle D. Williams, Christopher J. Howlett, Paul Plantinga, Matthew J. Cecchini, Alfred K. Lam, Iram Siddiqui, Jianxin Wang, Ren X. Sun, John D. Watson, Reju Korah, Tobias Carling, Nishant Agrawal, Nicole Cipriani, Douglas Ball, Barry Nelkin, Lisa M. Rooper, Justin A. Bishop, Cathie Garnis, Ken Berean, Norman G. Nicolson, Paul Weinberger, Ying C. Henderson, Christopher M. Lalansingh, Mao Tian, Takafumi N. Yamaguchi, Julie Livingstone, Adriana Salcedo, Krupal Patel, Frederick Vizeacoumar, Alessandro Datti, Liu Xi, Yuri E. Nikiforov, Robert Smallridge, John A. Copland, Laura A. Marlow, Martin D. Hyrcza, Leigh Delbridge, Stan Sidhu, Mark Sywak, Bruce Robinson, Kevin Fung, Farhad Ghasemi, Keith Kwan, S. Danielle MacNeil, Adrian Mendez, David A. Palma, Mohammed I. Khan, Mushfiq Shaikh, Kara M. Ruicci, Bret Wehrli, Eric Winquist, John Yoo, Joe S. Mymryk, James W. Rocco, David Wheeler, Steve Scherer, Thomas J. Giordano, John W. Barrett, William C. Faquin, Anthony J. Gill, Gary Clayman, Paul C. Boutros, Anthony C. Nichols
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113826- (2024)
Summary: Anaplastic thyroid carcinoma is arguably the most lethal human malignancy. It often co-occurs with differentiated thyroid cancers, yet the molecular origins of its aggressivity are unknown. We sequenced tumor DNA from 329 regions of thyroid
Externí odkaz:
https://doaj.org/article/c5a6abf2e7ba48ce977235cab50cb266
Publikováno v:
Cell Reports: Methods, Vol 3, Iss 11, Pp 100637- (2023)
Summary: Peptide-domain interactions mediated by short linear motifs (SLiMs) play crucial roles in cellular biology. The simplicity of SLiMs poses challenges in their computational identification. Existing high-throughput methods for discovering SLiM
Externí odkaz:
https://doaj.org/article/c35a7d060ef843c0a19ec493ec20de9d
Autor:
Steven F. Gameiro, Mikhail Y. Salnikov, Peter Y. F. Zeng, John W. Barrett, Anthony C. Nichols, Joe S. Mymryk
Publikováno v:
Viruses, Vol 15, Iss 12, p 2411 (2023)
Human papillomavirus (HPV) is the major causative agent for cervical and many head and neck cancers (HNCs). HPVs randomly acquire single nucleotide polymorphisms (SNPs) that may become established via positive selection. Within an HPV type, viral iso
Externí odkaz:
https://doaj.org/article/8cdc15fdb1154c088967c5e89ad98748
Autor:
Nicole Pinto, Kara M. Ruicci, Mohammed Imran Khan, Mushfiq Hassan Shaikh, Yu Fan Peter Zeng, John Yoo, Kevin Fung, S. Danielle MacNeil, Adrian Mendez, Joe S. Mymryk, John W. Barrett, Paul C. Boutros, Anthony C. Nichols
Publikováno v:
Journal of Otolaryngology - Head and Neck Surgery, Vol 51, Iss 1, Pp 1-10 (2022)
Abstract Anaplastic thyroid cancer (ATC) is a rare, aggressive form of undifferentiated thyroid cancer, which exhibits rapid progression and is almost universally fatal. At least a subset of ATC is thought to arise from pre-existing well-differentiat
Externí odkaz:
https://doaj.org/article/1d4bd87a76b449ceb48baa3fbf13dd24
Autor:
Peter Y.F. Zeng, Matthew J. Cecchini, John W. Barrett, Matthew Shammas-Toma, Loris De Cecco, Mara S. Serafini, Stefano Cavalieri, Lisa Licitra, Frank Hoebers, Ruud H. Brakenhoff, C. René Leemans, Kathrin Scheckenbach, Tito Poli, Xiaowei Wang, Xinyi Liu, Francisco Laxague, Eitan Prisman, Catherine Poh, Pinaki Bose, Joseph C. Dort, Mushfiq H. Shaikh, Sarah E.B. Ryan, Alice Dawson, Mohammed I. Khan, Christopher J. Howlett, William Stecho, Paul Plantinga, Sabrina Daniela da Silva, Michael Hier, Halema Khan, Danielle MacNeil, Adrian Mendez, John Yoo, Kevin Fung, Pencilla Lang, Eric Winquist, David A. Palma, Hedyeh Ziai, Antonio L. Amelio, Shawn S-C. Li, Paul C. Boutros, Joe S. Mymryk, Anthony C. Nichols
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104373- (2022)
Summary: Background: There is significant interest in treatment de-escalation for human papillomavirus-associated (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) patients given the generally favourable prognosis. However, 15–30% of patients re
Externí odkaz:
https://doaj.org/article/1fa6271669f0432eb67d2b929bab5f9f
Publikováno v:
Cancers, Vol 15, Iss 12, p 3178 (2023)
Epstein–Barr virus (EBV) is a gamma-herpesvirus associated with nearly 10% of gastric cancers (GCs). These EBV-associated GCs (EBVaGCs) are molecularly, histopathologically, and clinically distinct from EBV-negative GCs (EBVnGCs). While viral genes
Externí odkaz:
https://doaj.org/article/b3e81db671d0427b99b79664b18412b1
Autor:
Mikhail Salnikov, Steven F. Gameiro, Peter Y. F. Zeng, John W. Barrett, Anthony C. Nichols, Joe S. Mymryk
Publikováno v:
mSphere, Vol 7, Iss 4 (2022)
ABSTRACT Human papillomaviruses (HPVs) are highly infectious and cause the most common sexually transmitted viral infections. They induce hyperproliferation of squamous epithelial tissue, often forming warts. Virally encoded proteins reprogram gene e
Externí odkaz:
https://doaj.org/article/2657d1b773dc485f89420a45ebcca125
Autor:
Mikhail Y. Salnikov, Eric Wang, Erik Christensen, Martin A. Prusinkiewicz, Parisa Shooshtari, Joe S. Mymryk
Publikováno v:
Viruses, Vol 15, Iss 4, p 853 (2023)
Epstein-Barr virus (EBV) causes lifelong infection in over 90% of the world’s population. EBV infection leads to several types of B cell and epithelial cancers due to the viral reprogramming of host-cell growth and gene expression. EBV is associate
Externí odkaz:
https://doaj.org/article/d164e16836c74e08a27f7e8270b532bd