Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Joe Ortolani"'
Autor:
Matt Mahoney, Alex Shimozono, Evan Crawford, Rene P.F. Kanters, James A. Sikorski, Raymond N. Dominey, Jeffrey Noble, Campbell Heese, John T. Gupton, Evan Clark, Daniel C. Fisher, Emma W. Goldman, Carlos Perez Mandry, Joe Ortolani
Publikováno v:
Tetrahedron. 74:2650-2663
Highly functionalized pyrroles with appropriate regiochemical functionality represent an important class of marine natural products and potential drug candidates. We describe herein a detailed study of the reaction of α-aminoacid esters with vinylog
Autor:
Jon Patteson, Ellis Huff, Ahmad J. Obaidullah, James A. Sikorski, Alex Shimozono, John T. Gupton, Evan Crawford, Scott Yeudall, Nakul Telang, Wen Juekun, Cristina C. Rohena, Joe Ortolani, Andrew Harrison, Michael Kimmel, Kristin Lescalleet, Susan L. Mooberry, William Curry, Megan E. Hoerrner, Veronica Moore-Stoll, Katie Lounsbury, Glen E. Kellogg
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:3206-3214
New microtubule depolymerizing agents with potent cytotoxic activities have been prepared with a 5-cyano or 5-oximino group attached to a pyrrole core. The utilization of ortho activation of a bromopyrrole ester to facilitate successful Suzuki-Miyaur