Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Joe Media"'
Autor:
Xiaojuan Wang, Ken Swartz, Paul M. Stemmer, Mark T. Hamann, Jiajiu Shaw, Nicholas J. Carruthers, Frederick A. Valeriote, Joe Media, Nicholas Aube
Publikováno v:
J Proteomics
Methicillin-resistant S aureus (MRSA) contributes to patient mortality and extended hospital stays. 3-O-alpha-L-(2″,3″-di-p-coumaroyl)rhamnoside (KCR) is a natural product antibiotic that is effective against MRSA but has no known mechanism of ac
Autor:
Joe Media, Frederick A. Valeriote, Ben Chen, Halina Pietraszkiewicz, Jayshree Mishra, Peter R. Andreana, Matthew Edelstein, Jiajiu Shaw, Hao Jiang, Jean P. Bourgault, Narendra Kumar, Kevin R. Bobbitt
Publikováno v:
American Journal of Biomedical Sciences. :14-25
A new series of isoxazole derivatives, N-phenyl-5-carboxamidyl isoxazoles, was investigated for their anticancer activity with solid tumor selectivity. Six N-phenyl-5-carboxamidylisoxazoles were chemically synthesized and evaluated by the in vitro di
Autor:
Sandra A. Rempel, Alexander Nakeff, George Divine, Satya V. Vadlamuri, Steadman S. Sankey, Joe Media
Publikováno v:
Neuro-Oncology. 5:244-254
Secreted protein acidic and rich in cysteine (SPARC) has a suppressive effect on U87 glioma cell proliferation when assessed in vitro and in vivo using parental U87T2 and U87T2-derived SPARC-transfected clones. Since SPARCinteracts with extracellular
Autor:
Halina Pietraszkiewicz, Frederick A. Valeriote, Joe Media, Jon Clardy, Emil B. Lobkovsky, Phillip Crews, Zia Thale, Tyler A. Johnson, Philip J. Wenzel, Karen Tenney
Publikováno v:
The Journal of Organic Chemistry. 67:9384-9391
A reinvestigation of sponge natural products from additional Indo-Pacific collections of Xestospongiacf. carbonaria and X. cf. exigua has provided further insights on the structures, biological activities, and biosynthetic origin of bisannulated acri
Publikováno v:
Investigational New Drugs. 16:199-204
Cryptophycin 1 is a natural product that was initially isolated from blue-green algae which has shown potent broad spectrum antitumor activity in preclinical in vitro and in vivo models. The drug strongly binds to tubulin and disrupts microtubule ass
Autor:
Joe Media, Kevin R. Bobbitt, Peter R. Andreana, Halina Pietraszkiewicz, Ravindra A. De Silva, Jia Jiu Shaw, Fred A. Valeriote, Dananjaya K. Appulage
Publikováno v:
Cancer immunology, immunotherapy : CII. 61(4)
The tumor-associated carbohydrate antigen/hapten Thomsen-nouveau (Tn; α-D-GalpNAc-ONH2) was conjugated to a zwitterionic capsular polysaccharide, PS A1, from commensal anaerobe Bacteroides fragilis ATCC 25285/NCTC 9343 for the development of an enti