Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Joe Fullerton"'
Publikováno v:
CSU Journal of Sustainability and Climate Change. 2
Autor:
John R. Fozard, Martin Gosling, David Farr, Lynne Jordan, David A. Sykes, Darryl Brynley Jones, David Beattie, Joe Fullerton, Lyndon Nigel Brown, Julia Hatto, Rachel Profit, Mark Mercer, Diana Janus, Christine Lewis, Helen Oakman, Robin Alec Fairhurst, Friedrich Schuerch, Michelle Bradley, Nicola Arnold, Roger J. Taylor, Janet Maas, Steven J. Charlton, Andrew Brearley, Andrew R. Tuffnell, Alexandre Trifilieff, Clive Mccarthy, Neil John Press
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:4341-4347
The optimisation of two series of 4-hydroxybenzothiazolone derived β2-adrenoceptor agonists, bearing α-substituted cyclopentyl and β-phenethyl amino-substituents, as inhaled long-acting bronchodilators is described. Analogues were selected for syn
Autor:
John R. Fozard, Thomas H. Keller, Robin Alec Fairhurst, Alan Steward, Bernard Faller, David Bentley, Ian N. Bruce, David A. Sykes, David Beattie, John Reilly, Zhengjin Jiang, Joe Fullerton, David Beer, Christine Lewis, Frederique Loeuillet-Ritzler, Claire Hayden, Heinz E. Moser, Alexandre Trifilieff, Bernard Cuenoud, Steven J. Charlton, Lauren M. Tedaldi, Colin Howes, Elke Wissler, François Baur, Simon J. Watson, Morris Tweed, Julia Hatto, Sheila Garman, Roland Ernst, Handan He, Diana Janus, Daniel Wyss, Michelle Bradley, David Farr
Publikováno v:
Journal of medicinal chemistry. 53(9)
Following a lipophilicity-based hypothesis, an 8-hydroxyquinolinone 2-aminoindan derived series of beta(2)-adrenoceptor agonists have been prepared and evaluated for their potential as inhaled ultralong-acting bronchodilators. Determination of their