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pro vyhledávání: '"Joe Eckman"'
Autor:
Chen Christine Hiu-Tung, Remiszewski Stacy W, Jianmei Fan, Alex Fekete, Brant Firestone, Joseph D. Growney, Christopher T. Meta, Joe Eckman, Dyuti Majumdar, Ping Wang, Peter Atadja, Vinita Uttamsingh, Liping Zhou, Laszlo Urban, Qiang Lu, Meier Hsu, Suzanne Skolnik, Lei Jiang, Tim Ramsey, Martin Traebert, Yan Yan-Neale, Minying Pu, Julie Flynn, Lawrence Blas Perez, Yung-Mae Yao, Xueying Cao, Franco Lombardo, Steven Whitebread, Mats Holmqvist, Lewis Whitehead, Young Shin Cho, Paul Kwon, N Davis, Jack Green, Daniel Jansson, Michael Shultz, Gang Liu
Publikováno v:
Journal of Medicinal Chemistry. 54:4752-4772
Histone deacetylase (HDAC) inhibitors have shown promise in treating various forms of cancer. However, many HDAC inhibitors from diverse structural classes have been associated with QT prolongation in humans. Inhibition of the human ether a-go-go rel