Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Joe B. Jenkins"'
Autor:
Sujin Lee, Minh Trang Nguyen, Michael G. Currier, Joe B. Jenkins, Elizabeth A. Strobert, Adriana E. Kajon, Ranjna Madan-Lala, Yury A. Bochkov, James E. Gern, Krishnendu Roy, Xiaoyan Lu, Dean D. Erdman, Paul Spearman, Martin L. Moore
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
Existence of 150–170 serologically distinct human rhinoviruses (HRV) has hampered vaccine development for this human pathogen. Here, the authors show that a prime-boost regimen with an inactivated 50-valent HRV vaccine induces neutralizing antibody
Externí odkaz:
https://doaj.org/article/1472e837dd8b4360bb69aa5950313aef
Autor:
Elizabeth Strobert, Laura B. Higginbotham, Alfred Joseph Tector, Joseph M. Ladowski, Andrew B. Adams, Eric M. Walters, David V. Mathews, Alton B. Farris, Joe B. Jenkins, Gregory Martens, Cynthia P. Breeden, Christian P. Larsen, Allison Stephenson, Matthew Tector, Steven C. Kim
Publikováno v:
Am J Transplant
The shortage of available organs remains the greatest barrier to expanding access to transplantation. Despite advances in genetic editing and immunosuppression, survival in experimental models of kidney xenotransplantation has generally been limited
Autor:
W. C. Wakwe, Cynthia A. Breeden, Michael C. Lowe, Andrew B. Adams, Alton B. Farris, Mandy L. Ford, Robert M. Townsend, Mustimbo Roberts, David V. Mathews, Joe B. Jenkins, Christian P. Larsen, Steven C. Kim, Elizabeth Strobert
Publikováno v:
American Journal of Transplantation. 17:2285-2299
Recently, newer therapies have been designed to more specifically target rejection in an effort to improve efficacy and limit unwanted toxicity. Belatacept, a CD28-CD80/86 specific reagent, is associated with superior patient survival and graft funct
Autor:
Douglas J. Anderson, Elizabeth Strobert, Joe B. Jenkins, Denise J. Lo, Mingqing Song, Francis Leopardi, Allan D. Kirk, Christian P. Larsen
Publikováno v:
Clin Transplant
Belatacept, the CD28-B7 costimulation pathway inhibitor, has been approved as a calcineurin inhibitor (CNI) alternative in kidney transplantation. Although costimulation blockade (CoB) allows for CNI avoidance, it is associated with increased rates o
Autor:
Adriana E. Kajon, James E. Gern, Sujin Lee, Xiaoyan Lu, Martin L. Moore, Elizabeth Strobert, Yury A. Bochkov, Paul Spearman, Krishnendu Roy, Joe B. Jenkins, Ranjna Madan-Lala, Dean D. Erdman, Minh Trang Nguyen, Michael G. Currier
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
Nature Communications
Nature Communications
As the predominant aetiological agent of the common cold, human rhinovirus (HRV) is the leading cause of human infectious disease. Early studies showed that a monovalent formalin-inactivated HRV vaccine can be protective, and virus-neutralizing antib
Autor:
Allan D. Kirk, Francis Leopardi, Keith A. Reimann, Christian P. Larsen, Denise J. Lo, Joe B. Jenkins, Nicole A. Turgeon, Mingqing Song, Rijian Wang, Douglas J. Anderson, Elizabeth Strobert
Publikováno v:
American Journal of Transplantation. 16:1456-1464
Costimulation blockade with the fusion protein belatacept provides a desirable side effect profile and improvement in renal function compared with calcineurin inhibition in renal transplantation. This comes at the cost of increased rates of early acu
Autor:
Bradley H. Collins, J. Cano, Michael C. Lowe, Joe B. Jenkins, Peter W. Thompson, Benjamin M. Martin, Kannan P. Samy, C.R. Dove, F. Leopardi, Elizabeth Strobert, Alton B. Farris, M. Song, Christian P. Larsen, Allan D. Kirk
Publikováno v:
American Journal of Transplantation. 15:1241-1252
Islet xenotransplantation is a potential treatment for diabetes without the limitations of tissue availability. Although successful experimentally, early islet loss remains substantial and attributed to an instant blood mediated inflammatory reaction
Publikováno v:
Lab Animal. 48:188-188
Autor:
Elizabeth Strobert, Joe B. Jenkins, Jennifer Cheeseman, Stuart J. Knechtle, Eugenia K. Page, Prachi Sharma, Cynthia L. Courtney
Publikováno v:
Experimental and Toxicologic Pathology. 65:1019-1024
Human post-transplant lymphoproliferative disorder (PTLD) is an abnormal lymphoid proliferation that arises in 1–12% of transplant recipients as a consequence of prolonged immunosuppression and Epstein–Barr viral infection (EBV). Nonhuman primate
Fc-Silent Anti-CD154 Domain Antibody Effectively Prevents Nonhuman Primate Renal Allograft Rejection
Autor:
Christian P. Larsen, Anish Suri, Elizabeth Strobert, Aaron P. Yamniuk, Steven G. Nadler, Steven C. Kim, Thomas C. Pearson, Walter Wakwe, Cynthia P. Breeden, Robert Kuhn, Andrew B. Adams, Mandy L. Ford, Haiqing Wang, Joe B. Jenkins, Allison Stephenson, David V. Mathews, Karen Price, Suzanne J. Suchard, Laura B. Higginbotham, Alton B. Farris, Laura Price
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 17(5)
The advent of costimulation blockade provides the prospect for targeted therapy with improved graft survival in transplant patients. Perhaps the most effective costimulation blockade in experimental models is the use of reagents to block the CD40/CD1