Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jody S. Sylvia"'
Autor:
Cashell E. Jaquish, Craig P. Hersh, Emily Barron-Casella, Larry Phillips, James S. Pankow, JoAnn E. Manson, Mariza de Andrade, Vivien A. Sheehan, Norann A. Zaghloul, Yongmei Liu, Sergei Nekhai, Russell P. Tracy, Bruce S. Weir, Pankaj Qasba, Adrienne M. Stilp, Tasha E. Fingerlin, Heather M. Ochs-Balcom, L. Adrienne Cupples, Rongze Yang, David A. Schwartz, Shannon Kelly, Scott E. Devine, Tanja Smith, G.L. Kinney, Beverly Snively, Kent D. Taylor, Manolis Kellis, Ruth J. F. Loos, Seth A. Ament, Kathleen C. Barnes, Robert C. Kaplan, Ulrich Broeckel, Hemant K. Tiwari, Karin F. Hoth, Peter Durda, Julie L. Mikulla, Charles B. Eaton, Cotton Seed, Merry Lynn McDonald, Eric Boerwinkle, Josh Smith, Honghuang Lin, Ingrid B. Borecki, Jeffrey L. Curtis, Emelia J. Benjamin, Kenneth Rice, Sharon L.R. Kardia, Nicholas L. Smith, Coleen M. Damcott, Jeffrey Haessler, Kimberly L. Jones, Elaine Cornell, Nona Sotoodehnia, Adolfo Correa, Rich Johnston, C. Charles Gu, Chii Min Hwu, Peter C. Anderson, Lesley F. Tinker, Colleen Davis, R. Graham Barr, Scott T. Weiss, Leanna Farnam, Chao Hsiung, Brian Silver, Patrick F. McArdle, Lisa W. Martin, Yii-Der Ida Chen, John Barnard, Holly Kramer, Sekar Kathiresan, Gonçalo R. Abecasis, Barry Make, Michael C. Mahaney, Marco V Perez, Donna K. Arnett, Mark Chaffin, Xiuqing Guo, Joshua C. Bis, Pamela Russell, Paul L. Auer, James G. Wilson, Marilyn J. Telen, David K. Levine, Jennifer A. Smith, Christopher Scheller, Meher Preethi Boorgula, Aakrosh Ratan, Kari E. North, Dan E. Arking, Elizabeth A. Regan, Margaret G. Parker, Andres Metspalu, Jai G. Broome, Daniel Taliun, Lynette Ekunwe, Alyna T. Khan, Hao Mei, Dhananjay Vaidya, Ellen M. Schmidt, Stanford Mwasongwe, Joshua P. Lewis, Stacey Gabriel, Christine E. Seidman, Margery Gass, Deborah A. Nickerson, Nicola L. Hawley, Rebecca L. Beer, Afshin Parsa, Steven L. Salzberg, Terri H. Beaty, Stella Aslibekyan, Girish N. Nadkarni, Wei Zhao, David L. Tirschwell, Karen Bunting, Dawn L. DeMeo, Laura J. Rasmussen-Torvik, Julia Powers Becker, Dmitry Prokopenko, Karen Schwander, Bruce D. Gelb, Stephanie Krauter, Laura M. Raffield, Michael E. Hall, Frank C. Sciurba, Lauren Margolin, Nora Franceschini, Daniel N. Harris, Seyedeh M. Zekavat, Dawood Darbar, Keng-Han Lin, Haley Huston, Steven A. Lubitz, Andrea Ganna, Carole Sztalryd, Cathy C. Laurie, Christy Chang, James E. Hixson, Steven A. McCarroll, Barbara A. Konkle, Michael D. Kessler, Scott I. Vrieze, Yingze Zhang, Sarah Ruuska, George J. Papanicolaou, Weiniu Gan, Maris Alver, Elizabeth A. Streeten, Fei Fei Wang, Lu-Chen Weng, Braxton D. Mitchell, Lee-Ming Chuang, Sean P. David, Wei-Min Chen, Susan R. Heckbert, Ryan D. Hernandez, Andrew D. Johnson, Cristen J. Willer, Ani Manichaikul, Jonathan M. Bloom, Timothy D. O’Connor, Sylvia Smoller, Marguerite R. Irvin, Seung Hoan Choi, Ida Surakka, Veikko Salomaa, Diane M. Becker, Ron Do, W. Craig Johnson, Cecelia A. Laurie, Meryl S. LeBoff, Aniket Shetty, Tõnu Esko, Michael C. Zody, Xiaoqi Geng, Da Wei Gong, Snow Xueyan Zhao, Esteban G. Burchard, Xiuwen Zheng, Cara L. Carty, Alexander P. Reiner, Tim Assimes, Deborah A. Meyers, Mina K. Chung, Harald H H Göring, Benjamin M. Neale, Pradeep Natarajan, Yan Gao, Stephen S. Rich, Yun Ju Sung, Susan K. Dutcher, Ferdouse Begum, Stephanie M. Gogarten, John Blangero, Jonathan Cardwell, Kayleen Williams, Rakhi P. Naik, Amol C. Shetty, Sayantan Das, Myriam Fornage, May E. Montasser, Michelle Daya, Edwin K. Silverman, Daniel E. Weeks, Laura J. Kaufman, Dimitrios Avramopoulos, Michael Y. Tsai, Christine M. Albert, Vijay G. Sankaran, Jeffrey R. O'Connell, Thomas W. Blackwell, Stephen T. McGarvey, Robert M. Reed, Leslie A. Lange, Qing Duan, Bruce M. Psaty, Leslie S. Emery, Bertha Hidalgo, Jennifer A. Brody, L. Keoki Williams, Soren Germer, Zhaohui S. Qin, Deepti Jain, Deborah Applebaum-Bowden, Carla Wilson, Degui Zhi, Christoph Lange, Elliott Hong, L.F. Bielak, Wen Jane Lee, Yue Guan, Tarik Walker, Rebecca D. Jackson, Charles R. Farber, Mark J. Daly, Stephanie M. Fullerton, John E. Hokanson, Karol E. Watson, James Luo, Richard Casaburi, Seunggeun Lee, Jill M. Johnsen, Margaret A. Taub, Ryan L. Minster, Ravi Duggirala, Susan K. Mathai, Yun Li, Quenna Wong, Matthew Flickinger, Huichun Xu, Susan Redline, Ulrike Peters, Ivana V. Yang, Jesse M. Engreitz, Sanni Ruotsalainen, Sean K. McFarland, Avram D Walts, Patricia A. Peyser, Allison E. Ashley-Koch, Lewis C. Becker, Nicholette Palmer Allred, James A. Perry, Jody S. Sylvia, Tamar Sofer, Vasan S. Ramachandran, Laura Almasy, Matthew J. Budoff, Ranjan Deka, David M. Herrington, Simeon I. Taylor, Daniel Levy, Chaojie Yang, Sameer Chavan, Kathleen A. Ryan, Josyf C. Mychaleckyj, Ingo Ruczinski, Sebastian Zoellner, Michael Preuss, Tim Poterba, Wendy S. Post, Amber L. Beitelshees, Ben Heavner, Carolina Roselli, Namiko Abe, Jonathon LeFaive, Mark T. Gladwin, Brian Custer, Robert B. Wallace, Simin Liu, Michael H. Cho, Robert E. Handsaker, Dabeeru C. Rao, Bo Juen Chen, Wayne Hui Heng Sheu, Xiang Zhou, Marcos Bezerra, Solomon K. Musani, Eimear E. Kenny, James F. Casella, Kathryn L. Lunetta, Nancy Min, Nicholas Rafaels, Lisa R. Yanek, Min A. Jhun, David C. Glahn, Rasika A. Mathias, Mollie A. Minear, Russell P. Bowler, Jason Ernst, Carolyn J. Crandall, Sara Penchev, Alvaro Alonso, Timothy A. Thornton, Toni I. Pollin, Charles Kooperberg, Ethan M. Lange, Juan M. Peralta, Pramod Anugu, Lucinda Fulton, Adam A. Szpiro, Michael R. DeBaun, M. Benjamin Shoemaker, Sam Phillips, Dan M. Roden, Mao Fu, Daniel I. Chasman, James D. Crapo, Hua Tang, Gina M. Peloso, Hyun Min Kang, Samuli Ripatti, Phuwanat Sakornsakolpat, Christopher R. Gignoux, Peter VandeHaar, Jerome I. Rotter, Dandi Qiao, Emily S. Wan, Shabnam Salimi, Kevin Sandow, Jiang He, Patrick T. Ellinor, Joanne E. Curran
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature communications, vol 9, iss 1
Nature Communications
Nature communications, vol 9, iss 1
Nature Communications
Lipoprotein(a), Lp(a), is a modified low-density lipoprotein particle that contains apolipoprotein(a), encoded by LPA, and is a highly heritable, causal risk factor for cardiovascular diseases that varies in concentrations across ancestries. Here, we
Autor:
Blanca E. Himes, David A. Lomas, Barbara J. Klanderman, Dawn L. DeMeo, Craig P. Hersh, William MacNee, Elizabeth A. Regan, John E. Hokanson, Emily S. Wan, John Ziniti, Christoph Lange, Courtney Crim, Julie C. Yates, David Sparrow, Jacqueline B. Hetmanski, Alvar Agusti, Peter J. Castaldi, Lisa D. Edwards, Sreekumar G. Pillai, Bartolome R. Celli, Edwin K. Silverman, Jørgen Vestbo, Barry J. Make, Per Bakke, Mateusz Siedlinski, Peter M.A. Calverley, Terri H. Beaty, Xiangyang Kong, Michael H. Cho, Stephen I. Rennard, Tanda Murray, James D. Crapo, Wayne H. Anderson, Augusto A. Litonjua, Harvey O. Coxson, Emiel F.M. Wouters, Ruth Tal-Singer, Jody S. Sylvia, Amund Gulsvik
Publikováno v:
Human Molecular Genetics, 21(4), 947-957. Oxford University Press
The genetic risk factors for chronic obstructive pulmonary disease (COPD) are still largely unknown. To date, genome-wide association studies (GWASs) of limited size have identified several novel risk loci for COPD at CHRNA3/CHRNA5/IREB2, HHIP and FA
Autor:
Ross Lazarus, Christine A. Sorkness, Weiliang Qiu, Jessica Lasky-Su, Qing Ling Duan, Barbara J. Klanderman, Stephen P. Peters, Stanley J. Szefler, Mayumi Tamari, Fernando D. Martinez, John J. Lima, Augusto A. Litonjua, Amy Murphy, Blanca E. Himes, Jody S. Sylvia, Tomomitsu Hirota, Kelan G. Tantisira, David T. Mauger, Stephen C. Lazarus, Scott T. Weiss, Yusuke Nakamura, Christoph Lange, Robert F. Lemanske, Michishige Harada
Publikováno v:
New England Journal of Medicine. 365:1173-1183
The response to treatment for asthma is characterized by wide interindividual variability, with a significant number of patients who have no response. We hypothesized that a genomewide association study would reveal novel pharmacogenetic determinants
Autor:
James Murphy, Sungho Won, Emily S. Wan, Wayne Anderson, Sreekumar G. Pillai, Michael H. Cho, Barry J. Make, Amund Gulsvik, David A. Lomas, Elizabeth A. Regan, James D. Crapo, Emiel F.M. Wouters, Nadia Boutaoui, Barbara J. Klanderman, Jody S. Sylvia, John Ziniti, Bartolome R. Celli, Christoph Lange, Dawn L. DeMeo, Edwin K. Silverman, Per Bakke, Xiangyang Kong
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology, 45(2), 304-310. American Thoracic Society
Cachexia, whether assessed by body mass index (BMI) or fat-free mass index (FFMI), affects a significant proportion of patients with chronic obstructive pulmonary disease (COPD), and is an independent risk factor for increased mortality, increased em
Autor:
Frank D. Gilliland, James W. Baurley, Benjamin A. Raby, Ingo Ruczinski, Hita Vora, Scott T. Weiss, Sunita Sharma, George T. O'Connor, Nicholas Rafaels, W. James Gauderman, T.H. Beaty, Augustine M.K. Choi, Juan C. Celedón, Barbara J. Klanderman, Manuel E. Soto-Quiros, Jemma B. Wilk, Hong P. Kim, Blanca E. Himes, Rasika A. Mathias, Elliot Israel, Jessica Lasky-Su, Kathleen C. Barnes, Cara Bossley, Lydiana Avila, Jody S. Sylvia, Gary M. Hunninghake, Catherine Liang, Andrew Bush
Publikováno v:
Allergy. 65:1566-1575
Background Single nucleotide polymorphisms (SNPs) in thymic stromal lymphopoietin (TSLP) have been associated with IgE (in girls) and asthma (in general). We sought to determine whether TSLP SNPs are associated with asthma in a sex-specific fashion.
Autor:
Christoph Lange, Edwin K. Silverman, John Ziniti, Benjamin A. Raby, Amy Murphy, Ross Lazarus, Barbara J. Klanderman, Jessica Lasky-Su, Scott T. Weiss, Jody S. Sylvia, Angela J. Rogers, Juan C. Celedón
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 179:1084-1090
Rationale: Association studies have implicated many genes in asthma pathogenesis, with replicated associations between single-nucleotide polymorphisms (SNPs) and asthma reported for more than 30 genes. Genome-wide genotyping enables simultaneous eval
Publikováno v:
Pharmacogenetics and Genomics. 19:244-247
The two classes of leukotriene modifiers work by inhibiting different portions of the same pathway. We hypothesized that single nucleotide polymorphisms (SNPs) in genes associated with response to montelukast (a cys-leukotriene receptor antagonist) w
Autor:
Ngoc P. Ly, Manuel E. Soto-Quiros, Benjamin A. Raby, Jody S. Sylvia, Gary M. Hunninghake, Daniel Laskey, Juan C. Celedón, Lydiana Avila
Publikováno v:
Chest. 133:107-114
Background Little is known about the determinants of airway hyperresponsiveness (AHR) among children with asthma in Hispanic America. Methods We examined the relations among selected familial and environmental factors, markers of allergy, spirometric
Autor:
Craig P. Hersh, Jessica Lasky-Su, Lydiana Avila, Jody S. Sylvia, Manuel E. Soto-Quiros, Amy Murphy, Juan C. Celedón, Barbara J. Klanderman, Scott T. Weiss, Benjamin A. Raby, Christoph Lange
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 176:849-857
Rationale: Replication of gene-disease associations has become a requirement in complex trait genetics. Objectives: In studies of childhood asthma from two different ethnic groups, we attempted to replicate associations with five potential asthma sus
Autor:
Gary M. Hunninghake, Manuel E. Soto-Quiros, Amy Murphy, Juan C. Celedón, Lydiana Avila, Dawn L. DeMeo, Jody S. Sylvia, Catherine Liang, Edwin K. Silverman, Christoph Lange, Jessica Su, Ngoc P. Ly, Barbara J. Klanderman, Benjamin A. Raby
Publikováno v:
Journal of Allergy and Clinical Immunology. 120:84-90
Background It is unclear whether single nucleotide polymorphisms (SNPs) in the gene for IL-13 ( IL13 ) influence asthma severity and/or asthma morbidity. Objectives To examine the relation between IL13 SNPs and asthma-related phenotypes in 2 independ