Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Jody Rosenblatt"'
Autor:
Jody Rosenblatt
Publikováno v:
Current Biology. 26:R485-R487
Akademický článek
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Autor:
Jennifer Rynne, Elena Ortiz-Zapater, Dustin C. Bagley, Onofrio Zanin, George Doherty, Varsha Kanabar, Jon Ward, David J. Jackson, Maddy Parsons, Jody Rosenblatt, Ian M. Adcock, Rocio T. Martinez-Nunez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Asthma is the most common chronic inflammatory disease of the airways. The airway epithelium is a key driver of the disease, and numerous studies have established genome-wide differences in mRNA expression between health and asthma. How
Externí odkaz:
https://doaj.org/article/025cfd2596af4524902ab41889482181
Autor:
Elena Ortiz-Zapater, Dustin C. Bagley, Virginia Llopis Hernandez, Luke B. Roberts, Thomas J. A. Maguire, Felizia Voss, Philipp Mertins, Marieluise Kirchner, Isabel Peset-Martin, Grzegorz Woszczek, Jody Rosenblatt, Michael Gotthardt, George Santis, Maddy Parsons
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The epithelial protein Coxsackievirus Adenovirus Receptor (CAR) is a virus receptor but may have other functions. Here the authors show that deletion of CAR in mice leads to reduced house dust mite-induced lung inflammation, reduced neutrophil accumu
Externí odkaz:
https://doaj.org/article/c3d25d33aea74f4cbf6de6ff469281a8
Autor:
John Fadul, Teresa Zulueta-Coarasa, Gloria M. Slattum, Nadja M. Redd, Mauricio Franco Jin, Michael J. Redd, Stephan Daetwyler, Danielle Hedeen, Jan Huisken, Jody Rosenblatt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
The ability to visualise stochastic invasion events is limited in murine models of metastatic cancers. Here the authors use a transparent zebrafish epidermis model to follow the invasion events of K-Ras transformed epithelial cells and show that thes
Externí odkaz:
https://doaj.org/article/61d4a58f438f4d42b3f1128793ae1242
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105330- (2022)
Summary: Metastasis is tightly linked with poor cancer prognosis, yet it is not clear how transformed cells become invasive carcinomas. We previously discovered that single KRasV12-transformed cells can invade directly from the epithelium by basal ce
Externí odkaz:
https://doaj.org/article/f7547226e5044eef84e5060ef88bcd7d
Jody Rosenblatt: to extrude apically or basally, that is the question. Interview by Caitlin Sedwick.
Autor:
Rosenblatt J
Publikováno v:
The Journal of cell biology [J Cell Biol] 2013 Aug 19; Vol. 202 (4), pp. 602-3.
Akademický článek
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Publikováno v:
bioRxiv
Epithelial cells work collectively to provide a protective barrier, yet also turn over rapidly by cell death and division. If the number of dying cells does not match those dividing, the barrier would vanish, or tumors can form. Mechanical forces and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201047d048fc2f8ece895ef5a97a2f4c
https://doi.org/10.1101/2023.03.13.532421
https://doi.org/10.1101/2023.03.13.532421
Autor:
Saranne J Mitchell, Jody Rosenblatt
Publikováno v:
Curr Opin Cell Biol
Epithelial cells use the process of extrusion to promote cell death while preserving a tight barrier. To extrude, a cell and its neighbors contract actin and myosin circumferentially and basolaterally to seamlessly squeeze it out of the epithelium. R