Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jody L. Janecek"'
Establishment of Skeletal Myogenic Progenitors from Non-Human Primate Induced Pluripotent Stem Cells
Autor:
June Baik, Carolina Ortiz-Cordero, Alessandro Magli, Karim Azzag, Sarah B. Crist, Aline Yamashita, James Kiley, Sridhar Selvaraj, Ricardo Mondragon-Gonzalez, Elizabeth Perrin, John P. Maufort, Jody L. Janecek, Rachael M. Lee, Laura Hocum Stone, Parthasarathy Rangarajan, Sabarinathan Ramachandran, Melanie L. Graham, Rita C. R. Perlingeiro
Publikováno v:
Cells, Vol 12, Iss 8, p 1147 (2023)
Pluripotent stem (PS) cells enable the scalable production of tissue-specific derivatives with therapeutic potential for various clinical applications, including muscular dystrophies. Given the similarity to human counterparts, the non-human primate
Externí odkaz:
https://doaj.org/article/ca90a32d1b4844d29800015a149982ef
Autor:
Julia L. Nugent, Amar Singh, Keith M. Wirth, Scott Hunter Oppler, Laura Hocum Stone, Jody L. Janecek, Adam C. Sheka, Scott Kizy, Meghan E.G. Moore, Christopher Staley, Bernhard J. Hering, Sabarinathan Ramachandran, Sayeed Ikramuddin, Melanie L. Graham
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103421- (2021)
Summary: The obesity epidemic significantly contributes to overall morbidity and mortality. Bariatric surgery is the gold standard treatment for obesity and metabolic dysfunction, yet the mechanisms by which it exerts metabolic benefit remain unclear
Externí odkaz:
https://doaj.org/article/3fc8a538e22247af90c96b7b143479e7
Autor:
Robert W. Holdcraft, Melanie J. Graham, Melissa A. Bemrose, Lucas A. Mutch, Prithy C. Martis, Jody L. Janecek, Richard D. Hall, Barry H. Smith, Lawrence S. Gazda
Publikováno v:
Xenotransplantation. 29
Although human islet transplantation has proven to provide clinical benefits, especially the near complete amelioration of hypoglycemia, the supply of human islets is limited and insufficient to meet the needs of all people that could benefit from is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6679e33acc93a170a4947b4c52b473
https://doi.org/10.1111/xen.12747
https://doi.org/10.1111/xen.12747
Autor:
Timothy Carey, Sabarinathan Ramachandran, Lukkana Suksanpaisan, Samantha Reiter, Rachael M Z Lee, Chase Lathrum, Riya Narjari, Rianna Vandergaast, Alina Baum, Christopher D. Petro, Miguel Ángel Muñoz-Alía, Stephen J. Russell, Michelle Haselton, Christos A. Kyratsous, Patrcyja Lech, Lianwen Zhang, Melanie L. Graham, Jody L. Janecek, Karina Krotova, Clement W. Gnanadurai, Mulu Z. Tesfay, Nandakumar Packiriswamy, Toshie Sakuma, Kah Whye Peng, Kara Sevola, Jordan Recker, Luke Russell, Baskar Balakrishnan, Scott Waniger, Christopher Ziegler
Publikováno v:
Vaccine
An orally active vaccine capable of boosting SARS-CoV-2 immune responses in previously infected or vaccinated individuals would help efforts to achieve and sustain herd immunity. Unlike mRNA-loaded lipid nanoparticles and recombinant replication-defe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30be7219bf4507452322215cec68bc3a
https://doi.org/10.1101/2021.10.16.464660
https://doi.org/10.1101/2021.10.16.464660
Autor:
Amanda H. Klein, Kayla Johnson, Cole Fisher, Madelyn Moore, Amir Sadrati, Jody L. Janecek, Melanie L. Graham
Publikováno v:
The Journal of Pain. 23:16-17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45e8fc7033e527149b1e83efb136d139
https://doi.org/10.1016/j.jpain.2022.03.065
https://doi.org/10.1016/j.jpain.2022.03.065
Autor:
Adam C. Sheka, Jody L. Janecek, Christopher Staley, Scott Kizy, Scott Hunter Oppler, Laura Hocum Stone, Amar Singh, Julia L. Nugent, Sayeed Ikramuddin, Meghan E. G. Moore, Sabarinathan Ramachandran, Keith Wirth, Melanie L. Graham, Bernhard J. Hering
Publikováno v:
iScience
iScience, Vol 24, Iss 12, Pp 103421-(2021)
iScience, Vol 24, Iss 12, Pp 103421-(2021)
Summary The obesity epidemic significantly contributes to overall morbidity and mortality. Bariatric surgery is the gold standard treatment for obesity and metabolic dysfunction, yet the mechanisms by which it exerts metabolic benefit remain unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e6b65c5d733e18abce52d7b278ed3b
https://doi.org/10.1016/j.isci.2021.103421
https://doi.org/10.1016/j.isci.2021.103421
Autor:
Ce Yuan, James R. Dutton, Jody L. Janecek, Timothy O'Brien, Caitlin Hill, Anannya Banga, Lucas A. Mutch, Melanie L. Graham, Juan E. Abrahante
Publikováno v:
Human gene therapy. Clinical development. 28(2)
Type 1 diabetes manifests as autoimmune destruction of beta cells requiring metabolic management with an exogenous replacement of insulin, either by repeated injection of recombinant insulin or by transplantation of allogeneic islets from cadaveric d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbcfc178ebd6795339f5dba7463cddb
https://pubmed.ncbi.nlm.nih.gov/28363269
https://pubmed.ncbi.nlm.nih.gov/28363269
Autor:
Sarah C. Gresch, Jody L. Janecek, Lucas A. Mutch, Rebecca L. Hegstad-Davies, Melanie L. Graham, Sharon K. Hardy
Publikováno v:
Xenotransplantation. 22:62-69
Background Pre-clinical demonstration of porcine islet graft function is necessary to support the clinical transplantation of pig islets. C-peptide concentration is an especially useful marker of insulin secretion, because its measurement is not conf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a54e503bc70f7904a9b38b6ac8e96d4
https://doi.org/10.1111/xen.12143
https://doi.org/10.1111/xen.12143
Autor:
Lucas A. Mutch, Rebecca L. Hegstad-Davies, Melanie L. Graham, Jody L. Janecek, Sarah C. Gresch
Publikováno v:
Xenotransplantation. 24:e12320
Background C-peptide concentration is widely used as a marker of insulin secretion and is especially relevant in evaluating islet graft function following transplantation, because its measurement is not confounded by the presence of exogenous insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc64b04b1e42257dda8f5a0d23ddd19
https://doi.org/10.1111/xen.12320
https://doi.org/10.1111/xen.12320
Autor:
Melanie L, Graham, Jody L, Janecek, Jessica A, Kittredge, Bernhard J, Hering, Henk-Jan, Schuurman
Publikováno v:
Comparative medicine. 61(4)
Diabetes is induced in mice by using streptozotocin (STZ), a compound that has a preferential toxicity toward pancreatic β cells. We evaluated nude male mice from various sources for their sensitivity to a single high dose (160 to 240 mg/kg) of STZ.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e432832c359e5c180078c97f4a8fbdda
https://pubmed.ncbi.nlm.nih.gov/22330251
https://pubmed.ncbi.nlm.nih.gov/22330251