Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Jody E. Hooper"'
Autor:
Shuming Chen, Tracee L. McMiller, Abha Soni, Farah Succaria, John-William Sidhom, Laura C. Cappelli, Livia A. Casciola-Rosen, Isaac R. Morales, Preethi Sankaran, Alan E. Berger, Julie Stein Deutsch, Qingfeng C. Zhu, Robert A. Anders, Jody E. Hooper, Drew M. Pardoll, Evan J. Lipson, Janis M. Taube, Suzanne L. Topalian
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Tumor regression following immune checkpoint blockade (ICB) is often associated with immune-related adverse events (irAEs), marked by inflammation in non-cancerous tissues. This study was undertaken to investigate the functional r
Externí odkaz:
https://doaj.org/article/44edc95deb6444eabbd3e50a4991237d
Autor:
Kevin H. Toomer, Gloria F. Gerber, Yifan Zhang, Laetitia Daou, Michael Tushek, Jody E. Hooper, Ivo M. B. Francischetti
Publikováno v:
eJHaem, Vol 4, Iss 2, Pp 324-338 (2023)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection results in coagulation activation although it is usually not associated with consumption coagulopathy. D‐dimers are also commonly elevated despite systemic hypofibr
Externí odkaz:
https://doaj.org/article/6df57bfbd0cd4ecfaec3563339a660f5
Autor:
Varun Sagi, Nikitha Kosaraju, Lindsay S. Moore, Jip Y. Mulders, Mehmet Solyali, Xiaojie Ma, Donald P. Regula, Jody E. Hooper, Konstantina M. Stankovic
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Human temporal bones (HTBs) are invaluable resources for the study of otologic disorders and for evaluating novel treatment approaches. Given the high costs and technical expertise required to collect and process HTBs, there has been a decline in the
Externí odkaz:
https://doaj.org/article/76b200e223d44c0a8bc82f3de89c7c52
Autor:
Mengya Zhao, Kenichi Toma, Benyam Kinde, Liang Li, Amit K. Patel, Kong-Yan Wu, Matthew R. Lum, Chengxi Tan, Jody E. Hooper, Arnold R. Kriegstein, Anna La Torre, Yaping Joyce Liao, Derek S. Welsbie, Yang Hu, Ying Han, Xin Duan
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113038- (2023)
Summary: Chronic neurodegeneration and acute injuries lead to neuron losses via diverse processes. We compared retinal ganglion cell (RGC) responses between chronic glaucomatous conditions and the acute injury model. Among major RGC subclasses, αRGC
Externí odkaz:
https://doaj.org/article/1987370cf8584a7d92dea074efddcf38
Autor:
Livia Casciola-Rosen, David R. Thiemann, Felipe Andrade, Maria I. Trejo-Zambrano, Elissa K. Leonard, Jamie B. Spangler, Nicole E. Skinner, Justin Bailey, Srinivasan Yegnasubramanian, Rulin Wang, Ajay M. Vaghasia, Anuj Gupta, Andrea L. Cox, Stuart C. Ray, Raleigh M. Linville, Zhaobin Guo, Peter C. Searson, Carolyn E. Machamer, Stephen Desiderio, Lauren M. Sauer, Oliver Laeyendecker, Brian T. Garibaldi, Li Gao, Mahendra Damarla, Paul M. Hassoun, Jody E. Hooper, Christopher A. Mecoli, Lisa Christopher-Stine, Laura Gutierrez-Alamillo, Qingyuan Yang, David Hines, William A. Clarke, Richard E. Rothman, Andrew Pekosz, Katherine Z.J. Fenstermacher, Zitong Wang, Scott L. Zeger, Antony Rosen
Publikováno v:
JCI Insight, Vol 7, Iss 9 (2022)
Background Some clinical features of severe COVID-19 represent blood vessel damage induced by activation of host immune responses initiated by the coronavirus SARS-CoV-2. We hypothesized autoantibodies against angiotensin-converting enzyme 2 (ACE2),
Externí odkaz:
https://doaj.org/article/b514b606a0ee4c42affc7ad2f94c0c67
Autor:
Taejoon Won, Megan K. Wood, David M. Hughes, Monica V. Talor, Zexu Ma, Jowaly Schneider, John T. Skinner, Beejan Asady, Erin Goerlich, Marc K. Halushka, Allison G. Hays, Deok-Ho Kim, Chirag R. Parikh, Avi Z. Rosenberg, Isabelle Coppens, Roger A. Johns, Nisha A. Gilotra, Jody E. Hooper, Andrew Pekosz, Daniela Čiháková
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103812- (2022)
Summary: Background: Thromboembolism is a life-threatening manifestation of coronavirus disease 2019 (COVID-19). We investigated a dysfunctional phenotype of vascular endothelial cells in the lungs during COVID-19. Methods: We obtained the lung speci
Externí odkaz:
https://doaj.org/article/fa15652ffd1a47a2a1954f6284a33f0d
Autor:
Ivo M.B. Francischetti, Kevin Toomer, Yifan Zhang, Jayesh Jani, Zishan Siddiqui, Daniel J. Brotman, Jody E. Hooper, Thomas S. Kickler
Publikováno v:
EClinicalMedicine, Vol 39, Iss , Pp 101069- (2021)
Background: SARS-CoV-2 infection is associated with thrombotic and microvascular complications. The cause of coagulopathy in the disease is incompletely understood. Methods: A single-center cross-sectional study including 66 adult COVID-19 patients (
Externí odkaz:
https://doaj.org/article/b17b1d0611c3414abfb5f9cf23033c62
Autor:
Laura M. Wake MD, Derek B. Allison MD, Alisha D. Ware MD, Jody E. Hooper MD, Alex S. Baras MD, PhD, Evan M. Bloch MBChB, MS, William Clarke PhD, Kathleen H. Burns MD, PhD, Karen S. Sfanos MS, PhD, Michael J. Borowitz MD, PhD, Charles Steenbergen MD, PhD, Ralph H. Hruban MD, Marissa J. White MD
Publikováno v:
Academic Pathology, Vol 8 (2021)
Pathologists who enter the workforce must have a diverse skill set beyond that of clinical diagnostics alone. Anticipating this need, the Johns Hopkins Pathology Residency Program developed Special Expertise Tracks to enhance training in relevant sub
Externí odkaz:
https://doaj.org/article/a86339f24c504feabc4054c257fe2eee
Autor:
Narendra Bharathy, Noah E. Berlow, Eric Wang, Jinu Abraham, Teagan P. Settelmeyer, Jody E. Hooper, Matthew N. Svalina, Zia Bajwa, Martin W. Goros, Brian S. Hernandez, Johannes E. Wolff, Ranadip Pal, Angela M. Davies, Arya Ashok, Darnell Bushby, Maria Mancini, Christopher Noakes, Neal C. Goodwin, Peter Ordentlich, James Keck, Douglas S. Hawkins, Erin R. Rudzinski, Atiya Mansoor, Theodore J. Perkins, Christopher R. Vakoc, Joel E. Michalek, Charles Keller
Publikováno v:
Skeletal Muscle, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Background Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in the pediatric cancer population. Survival among metastatic RMS patients has remained dismal yet unimproved for years. We previously identified the class I-specific h
Externí odkaz:
https://doaj.org/article/61f97051a5764d4b94672ae99d9ce9fa
Autor:
Diane Armao, Thomas W. Bouldin, Rachel M. Bailey, Jody E. Hooper, Diana X. Bharucha, Steven J. Gray
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-5 (2019)
Abstract Giant axonal neuropathy (GAN; ORPHA: 643; OMIM# 256850) is a rare, hereditary, pediatric neurodegenerative disorder associated with intracellular accumulations of intermediate filaments (IFs). GAN knockout (KO) mouse models mirror the IF dys
Externí odkaz:
https://doaj.org/article/845fea1c9d2f488dba37dcde525c0bd7