Výsledky vyhledávání

Large-scale synthesis of Notum inhibitor 1-(2,4-dichloro-3-(trifluoromethyl)-phenyl)-1

Autor: Benjamin N, Atkinson, Nicky J, Willis, Jennifer, Smith, Rebecca, Gill, Jody, Ali, Zhou, Xu, Ping-Shan, Lai, Paul V, Fish

Publikováno v: RSC advances. 12(41)

1-Phenyl-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::30181eb9e0169a716f6a66ed1cd3f3de
https://pubmed.ncbi.nlm.nih.gov/36275171

Zobrazit plný text záznamu

Large-scale synthesis of Notum inhibitor 1-(2,4-dichloro-3-(trifluoromethyl)-phenyl)-1H-1,2,3-triazole (ARUK3001185) employing a modified Sakai reaction as the key step

Autor: Benjamin N. Atkinson, Nicky J. Willis, Jennifer Smith, Rebecca Gill, Jody Ali, Zhou Xu, Ping-Shan Lai, Paul V. Fish

1-Phenyl-1H-1,2,3-triazole 1 (ARUK3001185) was prepared on large scale from aniline 4 by application of both (1) a copper catalyzed azide-alkyne cycloaddition (CuAAC) with (trimethylsilyl)acetylene, and (2) a Clark modification of the Sakai reaction.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf0c4165b4fd2acdb0efbe7c2d45e04
https://doi.org/10.26434/chemrxiv-2022-4vzgh

Zobrazit plný text záznamu

Akademický článek

Large-scale synthesis of Notum inhibitor 1-(2,4-dichloro-3-(trifluoromethyl)-phenyl)-1H-1,2,3-triazole (ARUK3001185) employing a modified Sakai reaction as the key step.

Autor: Atkinson, Benjamin N., Willis, Nicky J., Smith, Jennifer, Gill, Rebecca, Ali, Jody, Xu, Zhou, Lai, Ping-Shan, Fish, Paul V.

Publikováno v: RSC Advances; 2022, Vol. 12 Issue 41, p26497-26503, 7p

Zobrazit plný text záznamu

Akademický článek

29th Annual GP2A Medicinal Chemistry Conference.

Autor: Helesbeux, Jean-Jacques¹ (AUTHOR) jean-jacques.helesbeux@univ-angers.fr, Carro, Laura² (AUTHOR) l.carro@ucl.ac.uk, McCarthy, Florence O.³ (AUTHOR) f.mccarthy@ucc.ie, Moreira, Vânia M.^4,5 (AUTHOR) vmoreira@ff.uc.pt, Giuntini, Francesca⁶ (AUTHOR) F.Giuntini@ljmu.ac.uk, O'Boyle, Niamh⁷ (AUTHOR) nioboyle@tcd.ie, Matthews, Susan E.⁸ (AUTHOR) susan.matthews@uea.ac.uk, Bayraktar, Gülşah⁹ (AUTHOR) gulsah.bayraktar@ege.edu.tr, Bertrand, Samuel¹⁰ (AUTHOR) samuel.bertrand@univ-nantes.fr, Rochais, Christophe¹¹ (AUTHOR) christophe.rochais@unicaen.fr, Marchand, Pascal¹² (AUTHOR) pascal.marchand@univ-nantes.fr

Publikováno v: Pharmaceuticals (14248247). Dec2021, Vol. 14 Issue 12, p1278-1278. 1p.

Zobrazit plný text záznamu

Elektronická kniha

Letters From the Lost Soul : A Five Year Voyage of Discovery and Adventure

Autor: Bob Bitchin

'Reading Bob's stories is almost better than hearing them firsthand. You get all the laughs and adventure...without the killer hangover!'--Cruising World'It seems as is Bob is spinning the world around under him rather than simply making his way acro

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání