Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jodie M. Hanesworth"'
Publikováno v:
Peptides. 20:915-920
Amino acid substitutions in positions two and three of angiotensin IV (VYIHPF) were carried out to determine which structural features of the side-chains were important for achieving high-affinity binding to bovine adrenal receptors. These studies de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f912c2045d8c71138a7e9538b1bcf44
https://doi.org/10.1016/s0196-9781(99)00081-9
https://doi.org/10.1016/s0196-9781(99)00081-9
Publikováno v:
Regulatory Peptides. 71:175-183
Angiotensin II (ANG II), acting principally at the AT1 receptor, modulates mechanically-induced cardiac growth. The ANG II metabolite Angiotensin IV (ANG IV) has been shown to inhibit ANG II-induced mRNA and protein synthesis in chick cardiomyocytes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8185b56ff66ae5227ce35f37f3eadd
https://doi.org/10.1016/s0167-0115(97)01033-1
https://doi.org/10.1016/s0167-0115(97)01033-1
Publikováno v:
Peptides. 15:1399-1406
The effect of structural changes in the N- terminal amino acid of AIV, with respect to AT4 receptor binding, was examined by competition with [125I]AIV in bovine adrenal membranes. Analogues with modifications of the first residue α-amino group poss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe405db65224364f41d5d7ea62394913
https://doi.org/10.1016/0196-9781(94)90115-5
https://doi.org/10.1016/0196-9781(94)90115-5
Publikováno v:
Peptides. 14:949-954
The ability of angiotensin IV (AIV) analogs to compete for [ 125 I]AIV binding in heat-treated bovine adrenal membranes was examined. Angiotensin IV displayed a K i of 2.63 ± 0.12 n M . Peptides containing mono-substitutions with glycine or the corr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb9847be2a5ff1ed60c5ac3330417f7
https://doi.org/10.1016/0196-9781(93)90071-n
https://doi.org/10.1016/0196-9781(93)90071-n
Autor:
Amy E. Ball, Howard L. Hosick, Keith L. Hall, Jodie M. Hanesworth, Joseph W. Harding, Grant P Felgenhauer
Publikováno v:
Regulatory Peptides. 44:225-232
This study demonstrates the existence of a previously unrecognized class of angiotensin binding sites on vascular smooth muscle that exhibit high affinity and specificity for the hexapeptide (3–8) fragment of angiotensin II (AngIV). Binding of [ 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a447528fa14d30d01af62d097dd5e982
https://doi.org/10.1016/0167-0115(93)90246-5
https://doi.org/10.1016/0167-0115(93)90246-5
Autor:
John W. Wright, Jodie M. Hanesworth, M.J. Shaffer, Allison V. Miller-Wing, Joseph W. Harding, Christopher I. Higginson, D.E. Wright
Publikováno v:
Brain Research Bulletin. 32:497-502
The present research characterizes a newly discovered ANG II(3–8) (ANG IV) binding site localized in structures associated with memory function (hippocampus, neocortex, cerebellum), as well as other brain stem structures (thalamus, inferior olivary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbd621c0225ce78488887388685778e
https://doi.org/10.1016/0361-9230(93)90297-o
https://doi.org/10.1016/0361-9230(93)90297-o
Autor:
Jodie M. Hanesworth, Michael F. Sardinia, John W. Wright, Allison V. Miller-Wing, Joseph W. Harding, Erin C. Harding, Jeffrey W. Stobb, Victoria I. Cook, J.K.M. Coleman, Geoffrey N. Swanson, Keith L. Hall
Publikováno v:
Regulatory Peptides. 40:409-419
We report here the discovery of a unique and novel angiotensin binding site and peptide system based upon the C-terminal 3-8 hexapeptide fragment of angiotensin II (NH3(+)-Val-Tyr-Ile-His-Pro-Phe-COO-) (AII(3-8) (AIV)). This fragment binds saturably,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf56e365796915382de3183b3ef6a74
https://doi.org/10.1016/0167-0115(92)90527-2
https://doi.org/10.1016/0167-0115(92)90527-2
Publikováno v:
Brain Research. 529:126-130
Rats received the aminopeptidase inhibitors amastatin (AM) and bestatin (BE), and carboxypeptidase inhibitor Plummer's (PL) via intracerebroventriclar infusion in various combinations, i.e. PL alone, AM + BE, and a cocktail consisting of AM + BE + PL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c69d70d61305ca469a6a38ef032e076
https://doi.org/10.1016/0006-8993(90)90819-w
https://doi.org/10.1016/0006-8993(90)90819-w
Publikováno v:
Peptides. 18(4)
Three hydroxyethylamine analogues of angiotensins II, III, and IV were prepared by solid-phase methods. The resin-bound peptide was alkylated with the iodomethylketone derivative of the N-terminal amino acid, followed by reduction to the alcohol usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e28a51d97575fa95616f38b9712885
https://pubmed.ncbi.nlm.nih.gov/9210168
https://pubmed.ncbi.nlm.nih.gov/9210168
Autor:
Jodie M. Hanesworth, John W. Wright, Joseph W. Harding, Michael F. Sardinia, Luke T. Krebs, EniköA. Kramár, Amy E. Ball
Publikováno v:
Regulatory peptides. 67(2)
Divalinal-Ang IV [Vψ(CH 2 -NH 2 )YVψ(CH 2 -NH 2 )HPF] is being employed increasingly as a specific AT 4 antagonist. This use, which necessitates a comprehensive physiological and pharmacological evaluation of Divalinal-Ang IV's functional and recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6be80fe606e359c9747004f3f754b41
https://pubmed.ncbi.nlm.nih.gov/8958583
https://pubmed.ncbi.nlm.nih.gov/8958583