Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Jodie L Babitt"'
Autor:
Brian Czaya, Kylie Heitman, Isaac Campos, Christopher Yanucil, Dominik Kentrup, David Westbrook, Orlando Gutierrez, Jodie L Babitt, Grace Jung, Isidro B Salusky, Mark Hanudel, Christian Faul
Publikováno v:
eLife, Vol 11 (2022)
Elevations in plasma phosphate concentrations (hyperphosphatemia) occur in chronic kidney disease (CKD), in certain genetic disorders, and following the intake of a phosphate-rich diet. Whether hyperphosphatemia and/or associated changes in metabolic
Externí odkaz:
https://doaj.org/article/81f9c42874cc4914b1511f208920ae5e
Autor:
Delphine Meynard, Chia Chi Sun, Qifang Wu, Wenjie Chen, Shanzhuo Chen, Caroline N Nelson, Michael J Waters, Jodie L Babitt, Herbert Y Lin
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82127 (2013)
TMPRSS6 is a regulated gene, with a crucial role in the regulation of iron homeostasis by inhibiting hepcidin expression. The main regulator of iron homeostasis, the antimicrobial peptide hepcidin, which also has a role in immunity, is directly upreg
Externí odkaz:
https://doaj.org/article/a503fcf8a1664141b6682d180abba1dd
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46307 (2012)
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor beta superfamily that exert their effects via type I and type II serine threonine kinase receptors and the SMAD intracellular signaling pathway to regulate diverse biolo
Externí odkaz:
https://doaj.org/article/fdfa3ef39e8042e999ac29ca3024202d
Autor:
Xinggang Wu, Lai-Ming Yung, Wai-Hang Cheng, Paul B Yu, Jodie L Babitt, Herbert Y Lin, Yin Xia
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44622 (2012)
Hepcidin is an antimicrobial peptide, which also negatively regulates iron in circulation by controlling iron absorption from dietary sources and iron release from macrophages. Hepcidin is synthesized mainly in the liver, where hepcidin is regulated
Externí odkaz:
https://doaj.org/article/4cdc57d9cda04969952c3737b2f75ada
Autor:
Yann Gibert, Victoria J Lattanzi, Aileen W Zhen, Lea Vedder, Frédéric Brunet, Sarah A Faasse, Jodie L Babitt, Herbert Y Lin, Matthias Hammerschmidt, Paula G Fraenkel
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14553 (2011)
Hemojuvelin (Hjv), a member of the repulsive-guidance molecule (RGM) family, upregulates transcription of the iron regulatory hormone hepcidin by activating the bone morphogenetic protein (BMP) signaling pathway in mammalian cells. Mammalian models h
Externí odkaz:
https://doaj.org/article/8e1830f57ce64936aee2ffba775e5122
Autor:
Allison L. Fisher, Chia-Yu Wang, Yang Xu, Sydney Phillips, Joao A. Paulo, Beata Małachowska, Xia Xiao, Wojciech Fendler, Joseph D. Mancias, Jodie L. Babitt
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108555- (2023)
Summary: Hepcidin is the master hormone governing systemic iron homeostasis. Iron regulates hepcidin by activating bone morphogenetic protein (BMP)6 expression in liver endothelial cells (LECs), but the mechanisms are incompletely understood. To addr
Externí odkaz:
https://doaj.org/article/ffcb1389eb464f2bbc0a5ef87272f676
Autor:
Artur Sargun, Allison L. Fisher, Anna S. Wolock, Sydney Phillips, Mozhdeh Sojoodi, Soumya Khanna, Jodie L. Babitt, Eric M. Gale
Publikováno v:
Journal of the American Chemical Society. 145:6871-6879
Autor:
Allison L. Fisher, Chia‐yu Wang, Yang Xu, Kole Joachim, Xia Xiao, Sydney Phillips, Gillian A. Moschetta, Victor M. Alfaro‐Magallanes, Jodie L. Babitt
Publikováno v:
American Journal of Hematology. 97:1548-1559
Systemic iron homeostasis is regulated by the hepatic hormone hepcidin to balance meeting iron requirements while limiting toxicity from iron excess. Iron-mediated induction of bone morphogenetic protein (BMP) 6 is a central mechanism for regulating
Autor:
Elaine Ku, Lucia Del Vecchio, Kai-Uwe Eckardt, Volker H. Haase, Kirsten L. Johansen, Masaomi Nangaku, Navdeep Tangri, Sushrut S. Waikar, Andrzej Więcek, Michael Cheung, Michel Jadoul, Wolfgang C. Winkelmayer, David C. Wheeler, Baris Afsar, Tadao Akizawa, Stefan D. Anker, Mustafa Arici, Jodie L. Babitt, Jonathan Barratt, Jeffrey S. Berns, Anatole Besarab, Sunil Bhandari, Christopher Brown, Aleix Cases, Glenn M. Chertow, Cynthia Delgado, Tillman B. Drüeke, Steven Fishbane, Rafael Gómez, Morgan E. Grams, Takayuki Hamano, Chuan-Ming Hao, Raymond K. Hsu, Kunitoshi Iseki, Isabelle Jordans, Edgar V. Lerma, Francesco Locatelli, Iain C. Macdougall, Jolanta Małyszko, Patrick Maxwell, Lawrence P. McMahon, Gregorio T. Obrador, Marlies Ostermann, Roberto Pecoits-Filho, Farzana Perwad, Simon D. Roger, Ajay K. Singh, Laura Solá, Bruce S. Spinowitz Mai Sugahara, Toshiyuki Takahashi, Mototsugu Tanaka, Tetsuhiro Tanaka, Der-Cherng Tarng, Marcello Tonelli, Yusuke Tsukamoto, Carl P. Walther, Angela Yee-Moon Wang, Bradley A. Warady, Angela C. Webster, Matthew R. Weir, Jay B. Wish, Muh Geot Wong
Publikováno v:
Kidney International.
Autor:
Suzy V. Torti, Frank M. Torti, Donna M. Peehl, Herbert Y. Lin, Jodie L. Babitt, Cindy K. Miranti, Tara Arvedson, Nicole Blanchette, Zhiyong Deng, Lance D. Miller, Xiaohong Wang, Poornima Hegde, Jin Woo Kim, Kathryn A. Clausen, Lia Tesfay
Supplemental Figures S1-S7. Hepcidin transcript levels in prostate cells under basal conditions and in response to modulation by signaling effectors (S1); Immunohistochemical detection of hepcidin in prostate tissue (S2); Clonegenic survival of DU145
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc67accb4e90abcb5359412dbb537a92
https://doi.org/10.1158/0008-5472.22405514.v1
https://doi.org/10.1158/0008-5472.22405514.v1