Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jodie K. Chin"'
Autor:
Ryan T Cirz, Jodie K Chin, David R Andes, Valérie de Crécy-Lagard, William A Craig, Floyd E Romesberg
Publikováno v:
PLoS Biology, Vol 3, Iss 6, p e176 (2005)
The emergence of drug-resistant bacteria poses a serious threat to human health. In the case of several antibiotics, including those of the quinolone and rifamycin classes, bacteria rapidly acquire resistance through mutation of chromosomal genes dur
Externí odkaz:
https://doaj.org/article/9528bccaaca344b591fade312f06350b
Publikováno v:
DNA Repair. 5:618-628
When replication forks stall during DNA synthesis, cells respond by assembling multi-protein complexes to control the various pathways that stabilize the replication machinery, repair the replication fork, and facilitate the reinitiation of processiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65f9b0b73c68d6ae6e52dcc95dcb0352
https://doi.org/10.1016/j.dnarep.2006.02.005
https://doi.org/10.1016/j.dnarep.2006.02.005
Autor:
Denise Hanway, Floyd E. Romesberg, Guy Oshiro, Jodie K. Chin, Elizabeth A. Winzeler, Gang Xia
Publikováno v:
Proceedings of the National Academy of Sciences. 99:10605-10610
A competitive growth assay has been used to identify yeast genes involved in the repair of UV- or MMS-induced DNA damage. A collection of 2,827 yeast strains was analyzed in which each strain has a single ORF replaced with a cassette containing two u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e81f8ae12da232dbd61f57431553a0
https://doi.org/10.1073/pnas.152264899
https://doi.org/10.1073/pnas.152264899
Autor:
Jian Liu, Malcolm G. P. Page, Peter A. S. Smith, Jodie K. Chin, Floyd E. Romesberg, Chuanyun Luo, Mark Paetzel
Publikováno v:
Journal of the American Chemical Society. 133(44)
Glycosylation of natural products, including antibiotics, often plays an important role in determining their physical properties and their biological activity, and thus their potential as drug candidates. The arylomycin class of antibiotics inhibits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9ffee003cc053dd0532e4f77a83c2d
https://pubmed.ncbi.nlm.nih.gov/21999324
https://pubmed.ncbi.nlm.nih.gov/21999324
Autor:
Valérie de Crécy-Lagard, Floyd E. Romesberg, Ryan Cirz, David R. Andes, Jodie K. Chin, William A. Craig
Publikováno v:
PLoS Biology, Vol 3, Iss 6, p e176 (2005)
PLoS Biology
PLoS Biology
The emergence of drug-resistant bacteria poses a serious threat to human health. In the case of several antibiotics, including those of the quinolone and rifamycin classes, bacteria rapidly acquire resistance through mutation of chromosomal genes dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1989a31b66b9c8495bdaf3a84b99bd4
https://doaj.org/article/9528bccaaca344b591fade312f06350b
https://doaj.org/article/9528bccaaca344b591fade312f06350b
Publikováno v:
Journal of the American Chemical Society. 124(9)
A recently developed method to directly observe specific protein vibrations, based on deuteration, has been employed to examine the redox-dependent structural and fluctional properties of cytochrome c. The dynamics of the protein-based methionine hem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d3bcc7635466fee9e07d7a3b4ce836
https://pubmed.ncbi.nlm.nih.gov/11866585
https://pubmed.ncbi.nlm.nih.gov/11866585
Publikováno v:
Biochemistry. 37(26)
The oxidation of alcohol to aldehyde by horse liver alcohol dehydrogenase (LADH) requires the transfer of a hydride ion from the alcohol substrate to the cofactor nicotinamide adenine dinucleotide (NAD). A quantum mechanical tunneling contribution to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e5e0223dee040fe0ad519b9a7dbc72
https://pubmed.ncbi.nlm.nih.gov/9649310
https://pubmed.ncbi.nlm.nih.gov/9649310
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 94(24)
We present evidence that the size of an active site side chain may modulate the degree of hydrogen tunneling in an enzyme-catalyzed reaction. Primary and secondary k H /k T and k D /k T kinetic isotope effects have been measured for the oxidation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed7ac89fcecb7b10af6168f279234f5
https://pubmed.ncbi.nlm.nih.gov/9371755
https://pubmed.ncbi.nlm.nih.gov/9371755
Publikováno v:
Journal of the American Chemical Society. 123:2426-2427
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5e176dc2b52dffaa319a6c2205f968
https://doi.org/10.1021/ja0033741
https://doi.org/10.1021/ja0033741