Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jodie C. McGuffin"'
Publikováno v:
European Journal of Pharmacology. 44:65-74
CPP, administered systemically, elicited four distinct responses characteristic of serotonin-receptor activation in the central nervous system. The crossed extensor reflex in the acutely spinalized rat was enhanced by treatment with CPP, 1–16 mg/kg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d201b278716c977545a30c9c0cd8f662
https://doi.org/10.1016/0014-2999(77)90117-0
https://doi.org/10.1016/0014-2999(77)90117-0
Publikováno v:
European Journal of Pharmacology. 35:211-214
A single oral dose of 15 mg/kg of fenfluramine reduced the level of serotonin in rat brain to 48, 51 and 63% of control at 1, 15 and 30 days, respectively, after administration. 3 mg/kg p.o. of the drug caused a smaller but significant diminution in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e6368a1a4b91c1ea75b4e223666298
https://doi.org/10.1016/0014-2999(76)90318-6
https://doi.org/10.1016/0014-2999(76)90318-6
Autor:
Anthony G. Zacchei, Bradley V. Clineschmidt, Jodie C. McGuffin, A. Barbara Pflueger, Theodore I. Wishousky, J. A. Totaro
Publikováno v:
Annals of the New York Academy of Sciences. 305:222-241
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab7b242d109238e92e7148781930ebd
https://doi.org/10.1111/j.1749-6632.1978.tb31526.x
https://doi.org/10.1111/j.1749-6632.1978.tb31526.x
A 5-HYDROXYTRYPTAMINE-LIKE MODE OF ANORECTIC ACTION FOR 6-CHLORO-2-[1-PIPERAZINYL]-PYRAZINE (MK-212)
Publikováno v:
British Journal of Pharmacology. 62:579-589
The mechanism of the reduction in food consumption elicited by 6-chloro-2-[1-piperazinyl]-pyrazine (MK-212) administered systemically was investigated in the rat. (+/-)-Fenfluramine and (+)-amphetamine were included in some studies for comparative pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1679d7ec0e39ddab62f19568feedc7
https://doi.org/10.1111/j.1476-5381.1978.tb07765.x
https://doi.org/10.1111/j.1476-5381.1978.tb07765.x
Autor:
Patricia R. Bunting, Jodie C. McGuffin, Ruby J. Ballentine, Bradley V. Clineschmidt, A. Barbara Pflueger
Publikováno v:
European Journal of Pharmacology. 32:279-286
BE-2254, 2-[beta-(4-hydroxyphenyl)-ethylaminomethyl]-tetralone, (ED50 = 3.4 mg/kg i.p.) was about equal to chlorpromazine (ED50 = 4.4) as an antagonist of central noradrenergic receptor stimulation produced by clonidine (enhancement of the flexor ref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efab388b1da7fcca1f0353e979ef3e58
https://doi.org/10.1016/0014-2999(75)90294-0
https://doi.org/10.1016/0014-2999(75)90294-0
Publikováno v:
European Journal of Pharmacology. 60:41-46
Administered by either intravenous (i.v.) or intracisternal (i.cis.) injections, MK-771 and TRH induced a dose-related increase in EMG activity recorded from the flexor ulnaris muscle in pentobarbital-anesthetized rats. By the i.v. route, MK-771 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77361b2100a5e0a35c6df48d56e569d3
https://doi.org/10.1016/0014-2999(79)90050-5
https://doi.org/10.1016/0014-2999(79)90050-5
Publikováno v:
European Journal of Pharmacology. 54:129-139
Neurotensin administered intracisternally in mice increased reaction time in the hot plate test (minimum effective dose = 25 ng) and decreased writhing induced by acetic acid (minimum effective dose = 0.25 ng). At the maximum effective dose of 250 ng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b606b41003d76cae0cfb5b7c9fae5d34
https://doi.org/10.1016/0014-2999(79)90415-1
https://doi.org/10.1016/0014-2999(79)90415-1
Publikováno v:
Journal of Pharmacy and Pharmacology. 27:780-782
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd60b3996826da44e3d69a8e2b716538
https://doi.org/10.1111/j.2042-7158.1975.tb09402.x
https://doi.org/10.1111/j.2042-7158.1975.tb09402.x
Publikováno v:
European journal of pharmacology. 50(4)
Three compounds believed to posses 5-hydroxytryptamine-like (5-HT-like) activity in the central nervous system (CNS) were studied in the suprahyoideal muscle twitch-frequency model. MK-212 (0.1 mg/kg), p-methoxy-amphetamine (p-MA; 0.75 mg/kg) and fen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d319c436e89d74249abe973e91b7bf0
https://pubmed.ncbi.nlm.nih.gov/151629
https://pubmed.ncbi.nlm.nih.gov/151629
Publikováno v:
Neuropharmacology. 14(4)
Fenfluramine, administered to rats at anorectic dose levels, reduced open field activity and enhanced confinement motor activity, demonstrating the mixed depressant and stimulant characteristics of the compound. Studies designed to elucidate the mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6eeb00e9bcf1a385e451b7977b8aab1
https://pubmed.ncbi.nlm.nih.gov/124023
https://pubmed.ncbi.nlm.nih.gov/124023