Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jodi L Lukkes"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 3 (2009)
Exposure to adverse experiences in early-life is implicated in the later vulnerability to development of psychiatric disorders, including anxiety and affective disorders in humans. Adverse early-life experiences likely impart their long-term conseque
Externí odkaz:
https://doaj.org/article/ce0dd3ad7d124d718a9521fb4a977f28
Publikováno v:
Neurobiology of Stress, Vol 9, Iss , Pp 29-39 (2018)
Early-life adversity is associated with increased risk for substance abuse in later life, with women more likely to report past and current stress as a mediating factor in their substance use and relapse as compared to men. Preclinical models of neon
Externí odkaz:
https://doaj.org/article/922df5642ac448b58c338c460e6c7947
Publikováno v:
Brain Sciences, Vol 3, Iss 1, Pp 143-158 (2013)
Early adverse experience is a well-known risk factor for addictive behaviors later in life. Drug addiction typically manifests during adolescence in parallel with the later-developing prefrontal cortex (PFC). While it has been shown that dopaminergic
Externí odkaz:
https://doaj.org/article/b9b8060f33f24020bba6334fb757f4b4
Autor:
Anantha Shekhar, Andrei I. Molosh, D. W. Clapp, H. P. Drozd, Jodi L. Lukkes, Stephanie D. Fitz
Publikováno v:
Journal of Neurodevelopmental Disorders
Journal of Neurodevelopmental Disorders, Vol 12, Iss 1, Pp 1-13 (2020)
Journal of Neurodevelopmental Disorders, Vol 12, Iss 1, Pp 1-13 (2020)
Background Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder with a mutation in one copy of the neurofibromin gene (NF1+/−). Even though approximately 40–60% of children with NF1 meet the criteria for attention deficit hyperactivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45f90d406e004b272d779aa117bd8d9
http://europepmc.org/articles/PMC6961243
http://europepmc.org/articles/PMC6961243
Publikováno v:
Psychopharmacology. 236:685-698
Both methylphenidate (MPH), a catecholamine reuptake blocker, and guanfacine, an alpha2A agonist, are used to treat attention-deficit hyperactivity disorder (ADHD). Childhood impulsivity, including delay discounting, is associated with increased subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ad3bf7b1dd9f79473509c96e8cbcc9
https://doi.org/10.1007/s00213-018-5096-0
https://doi.org/10.1007/s00213-018-5096-0
Autor:
Jared D. Heinze, Jodi L. Lukkes, Matthew W. Hale, Drake M. Kienzle, Philip H. Siebler, Jared M. Kopelman, Nina C. Donner, Orlando A. Rodriguez, Christopher A. Lowry
Publikováno v:
Cellular and Molecular Neurobiology. 38:289-304
Peripheral immune activation can have profound physiologic and behavioral effects. One mechanism through which immune activation may affect physiology and behavior is through actions on brainstem neuromodulatory systems, such as serotonergic systems.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8bcca434b2111c1b2638105c6c17369
https://doi.org/10.1007/s10571-017-0564-3
https://doi.org/10.1007/s10571-017-0564-3
Publikováno v:
Behavioural Brain Research. 330:37-45
Early life adversity (ELA) increases the risk of depression during adolescence that may result from a decline in parvalbumin (PVB) secondary to increased neuroinflammation. In this study, we investigated depressive-like behavior following exposure to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f405c6bd4cd611cb3f07420060efc41
https://doi.org/10.1016/j.bbr.2017.04.053
https://doi.org/10.1016/j.bbr.2017.04.053
Publikováno v:
European Neuropsychopharmacology. 26:1496-1506
Clinical and preclinical studies on attention deficit hyperactivity disorder (ADHD) show that juvenile males that are exposed to methylphenidate (MPH) show reduced risk for substance use later in life. In contrast, little is known about whether femal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0dca1da447ea8cd92e382135855405
https://doi.org/10.1016/j.euroneuro.2016.06.003
https://doi.org/10.1016/j.euroneuro.2016.06.003
Publikováno v:
Synapse. 70:125-132
Interactions between corticotropin-releasing factor (CRF) and monoaminergic systems originating from the dorsal raphe nucleus (DR) and ventral tegmental area (VTA) have been implicated in the etiology and pathophysiology of several stress-related neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6d9b27823edfcafdca44b00c7270255
https://doi.org/10.1002/syn.21882
https://doi.org/10.1002/syn.21882
Autor:
Hayley P, Drozd, Sotirios F, Karathanasis, Andrei I, Molosh, Jodi L, Lukkes, D Wade, Clapp, Anantha, Shekhar
Publikováno v:
Progress in brain research. 241
Autism spectrum disorders (ASD) represent a heterogeneous group of disorders defined by deficits in social interaction/communication and restricted interests, behaviors, or activities. Models of ASD, developed based on clinical data and observations,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a10454b2916ec4141caf93276149627c
https://pubmed.ncbi.nlm.nih.gov/30447753
https://pubmed.ncbi.nlm.nih.gov/30447753