Deep rTMS of the insula and prefrontal cortex in smokers with schizophrenia: Proof-of-concept study

Autor: Scott J. Moeller, Roberto Gil, Jodi J. Weinstein, Topaz Baumvoll, Kenneth Wengler, Natalka Fallon, Jared X. Van Snellenberg, Sameera Abeykoon, Greg Perlman, John Williams, Lucian Manu, Mark Slifstein, Clifford M. Cassidy, Diana M. Martinez, Anissa Abi-Dargham

Publikováno v: npj Schizophrenia, Vol 8, Iss 1, Pp 1-9 (2022)

Abstract Patients with schizophrenia have a high prevalence of cigarette smoking and respond poorly to conventional treatments, highlighting the need for new therapies. We conducted a mechanistic, proof-of-concept study using bilateral deep repetitiv

Externí odkaz: https://doaj.org/article/9b002a905e0f409283736774f8d7ba94

Cross-Scanner Harmonization of Neuromelanin-Sensitive MRI for Multisite Studies

Autor: Marieke van der Pluijm, Kenneth Wengler, Anissa Abi-Dargham, Jodi J. Weinstein, Guillermo Horga, Clifford M. Cassidy, Elsmarieke van de Giessen

Publikováno v: Journal of magnetic resonance imaging, 54(4), 1189-1199. John Wiley and Sons Inc.
J Magn Reson Imaging

Background: Neuromelanin-sensitive magnetic resonance imaging (NM-MRI) is a validated measure of neuromelanin concentration in the substantia nigra–ventral tegmental area (SN–VTA) complex and is a proxy measure of dopaminergic function with poten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ff77fa44b227af585f7dda14eb7647
http://www.scopus.com/inward/record.url?scp=85105140079&partnerID=8YFLogxK

Deep rTMS of the insula disrupts cigarette self-administration and modulates insula-centric brain function in smokers with schizophrenia

Autor: Natalka Fallon, Jared X. Van Snellenberg, Topaz Baumvoll, Mark Slifstein, Scott J. Moeller, Kenneth Wengler, Sameera Abeykoon, John W Williams, Lucian Manu, Jodi J. Weinstein, Roberto Gil, Clifford M. Cassidy, Anissa Abi-Dargham, Greg Perlman, Diana Martinez

Publikováno v: Brain Stimulation, Vol 14, Iss 5, Pp 1416-(2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8076ca3cfad73e664b3b8bb72719390c
http://www.sciencedirect.com/science/article/pii/S1935861X21001960

Neuromelanin-sensitive MRI as a noninvasive proxy measure of dopamine function in the human brain

Autor: Madeleine Sharp, Un Jung Kang, Jodi J. Weinstein, David Sulzer, Guillermo Horga, Chiara Bellei, Ragy R. Girgis, Luigi Zecca, Anissa Abi-Dargham, Lawrence S. Kegeles, Seth Baker, Clifford M. Cassidy, Fabio A. Zucca, Gary Brucato, Alice Valmadre, Nora Vanegas

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America 116 (2019): 5108–5117. doi:10.1073/pnas.1807983116
info:cnr-pdr/source/autori:Cassidy C.M.; Zucca F.A.; Girgis R.R.; Baker S.C.; Weinstein J.J.; Sharp M.E.; Bellei C.; Valmadre A.; Vanegas N.; Kegeles L.S.; Brucato G.; Kang U.J.; Sulzer D.; Zecca L.; Abi-Dargham A.; Horga G./titolo:Neuromelanin-sensitive MRI as a noninvasive proxy measure of dopamine function in the human brain/doi:10.1073%2Fpnas.1807983116/rivista:Proceedings of the National Academy of Sciences of the United States of America/anno:2019/pagina_da:5108/pagina_a:5117/intervallo_pagine:5108–5117/volume:116

Neuromelanin-sensitive MRI (NM-MRI) purports to detect the content of neuromelanin (NM), a product of dopamine metabolism that accumulates with age in dopamine neurons of the substantia nigra (SN). Interindividual variability in dopamine function may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d356607471df89e3341160bdec72bb
https://doi.org/10.1073/pnas.1807983116

Multi-Task Learning based 3-Dimensional Striatal Segmentation of MRI – a Multi-modal Objective Assessment

Autor: Anissa Abi-Dargham, Jodi J. Weinstein, Mario Serrano-Sosa, Chuan Huang, Mark Slifstein, Jiayan Meng, Karl Spuhler, Jared X. Van Snellenberg

The human striatum is a collection of subcortical nuclei that serves as a critical node in an information processing network. Recent studies have established a clear topographical and functional organization of projections to and from striatal region

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ddc7d844501fd8bd3292a3dc1fe86112
https://doi.org/10.1101/2020.07.13.200576