Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jodi I. Huggenvik"'
Autor:
Stacey R McGee, Shivakumar Rajamanickam, Sandeep Adhikari, Oluwatosin C Falayi, Theresa A Wilson, Brian J Shayota, Jessica A Cooley Coleman, Cindy Skinner, Raymond C Caylor, Roger E Stevenson, Caio Robledo D' Angioli Costa Quaio, Berenice Cunha Wilke, Jennifer M Bain, Kwame Anyane-Yeboa, Kaitlyn Brown, John M Greally, Emilia K Bijlsma, Claudia A L Ruivenkamp, Keren Politi, Lydia A Arbogast, Michael W Collard, Jodi I Huggenvik, Sarah H Elsea, Philip J Jensik
Publikováno v:
Hum Mol Genet
Human Molecular Genetics, 32(3), 386-401. OXFORD UNIV PRESS
Human Molecular Genetics, 32(3), 386-401. OXFORD UNIV PRESS
De novo deleterious and heritable biallelic mutations in the DNA binding domain (DBD) of the transcription factor deformed epidermal autoregulatory factor 1 (DEAF1) result in a phenotypic spectrum of disorders termed DEAF1-associated neurodevelopment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce133e0cb7ab0932b2f68c883c636406
https://hdl.handle.net/1887/3563136
https://hdl.handle.net/1887/3563136
Autor:
Raghuveer Kanneganti, Ryan P Coppens, Travis Healey, Kristin A. Wiggs, David G. Gilbert, Gregory M. Rose, Norka E. Rabinovich, Jodi I. Huggenvik, Herman Augustus Diggs
Publikováno v:
Psychopharmacology. 238:1171-1181
There is strong evidence that nicotine can enhance cognitive functions and growing evidence that this effect may be larger in young healthy APOE e4 carriers. However, the moderating effects of the APOE e4 allele on cognitive impairments caused by nic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f905ee98f66db211f00284b8dd2f6c4
https://doi.org/10.1007/s00213-021-05763-5
https://doi.org/10.1007/s00213-021-05763-5
Autor:
Philip J Jensik, Jesse D Vargas, Sara N Reardon, Shivakumar Rajamanickam, Jodi I Huggenvik, Michael W Collard
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115908 (2014)
DEAF1 is a transcriptional regulator associated with autoimmune and neurological disorders and is known to bind TTCG motifs. To further ascertain preferred DEAF1 DNA ligands, we screened a random oligonucleotide library containing an "anchored" CpG m
Externí odkaz:
https://doaj.org/article/dc2ed74694934ff1882625223f66a904
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33404 (2012)
Deformed Epidermal Autoregulatory Factor 1 (DEAF1) is a transcription factor linked to suicide, cancer, autoimmune disorders and neural tube defects. To better understand the role of DEAF1 in protein interaction networks, a GST-DEAF1 fusion protein w
Externí odkaz:
https://doaj.org/article/e1916b19639b4a978b9422fda022162d
Autor:
Jodi I. Huggenvik, Xiang Cai, Michael W. Collard, Anneke T. Vulto-van Silfhout, Shivakumar Rajamanickam, Joris A. Veltman, Bregje W.M. van Bon, Evan E. Eichler, Philip J. Jensik, Bert B.A. de Vries, Stacy Ownby, Alexander Hoischen, Dorien Lugtenberg, Joseph Bulinski, Arjan P.M. de Brouwer, Gregory M. Rose, Nina De Rocker, Gemma L. Carvill, Heather C Mefford, Ramya Raghavan, Björn Menten, Joep de Ligt, Kathryn J. Newhall, Sarah Vergult, G. Stanley McKnight, Lisenka E.L.M. Vissers, Han G. Brunner, Hans van Bokhoven, Christiane Zweier, Tara McIntyre, Andy Willaert, Petra de Vries, Sara Reardon, Kelsey Jarrett, Sabine Endele, Anita Rauch
Publikováno v:
American Journal of Human Genetics, 94, 5, pp. 649-61
American Journal of Human Genetics, 94, 649-61
The American Journal of Human Genetics; Vol 94
American Journal of Human Genetics, 94, 649-61
The American Journal of Human Genetics; Vol 94
Contains fulltext : 137502.pdf (Publisher’s version ) (Open Access) Recently, we identified in two individuals with intellectual disability (ID) different de novo mutations in DEAF1, which encodes a transcription factor with an important role in em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184d6f829ac573fa4aa8b126eb553590
Autor:
David Piquemal, Ken Saito, Sucharita Bandyopadhyay, Sudha K. Pai, Jodi I. Huggenvik, Shigeru Hirota, Ying Wang, Misako Watabe, Thérèse Commes, Yukio Takano, Kunio Miura, Kounosuke Watabe, Sadahiro Hosobe, Taisei Tsukada, Steven S. Gross
Publikováno v:
Cancer Research. 64:7655-7660
PTEN (phosphatase and tensin homologue deleted on chromosome 10) has been shown to be inactivated in a wide variety of cancers, and the role of this gene as a tumor suppressor has been well established. On the other hand, results of recent animal stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb4fb1c4cbdd12792130c89cdb6275c
https://doi.org/10.1158/0008-5472.can-04-1623
https://doi.org/10.1158/0008-5472.can-04-1623
Autor:
Jesse D. Vargas, Shivakumar Rajamanickam, Jodi I. Huggenvik, Sara Reardon, Philip J. Jensik, Michael W. Collard
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115908 (2014)
PLoS ONE
PLoS ONE
DEAF1 is a transcriptional regulator associated with autoimmune and neurological disorders and is known to bind TTCG motifs. To further ascertain preferred DEAF1 DNA ligands, we screened a random oligonucleotide library containing an “anchored” C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968a690ee195c847fed851d78a3870d8
http://europepmc.org/articles/PMC4274154?pdf=render
http://europepmc.org/articles/PMC4274154?pdf=render
Autor:
Zhihong Liu, Jodi I. Huggenvik, Toby J. Gibson, Michael Sattler, Matthew J. Bottomley, Michael W. Collard
Publikováno v:
Nature Structural Biology. 8:626-633
The SAND domain is a conserved sequence motif found in a number of nuclear proteins, including the Sp100 family and NUDR. These are thought to play important roles in chromatin-dependent transcriptional regulation and are linked to many diseases. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1599b0474b1a19ad4bac29e8d3b0f0e4
https://doi.org/10.1038/89675
https://doi.org/10.1038/89675
Autor:
Michael W. Collard, Jodi I. Huggenvik, Jim Persinger, Rhett J. Michelson, Amy J. Ziemba, Blaine Bartholomew
Publikováno v:
Journal of Biological Chemistry. 274:30510-30519
Nuclear DEAF-1-related (NUDR) protein is a novel transcriptional regulator with sequence similarity to developmental and oncogenic proteins. NUDR protein deletions were used to localize the DNA binding domain between amino acids 167 and 368, and site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc71eaa311e9b946e6afec515fc971d2
https://doi.org/10.1074/jbc.274.43.30510
https://doi.org/10.1074/jbc.274.43.30510
Autor:
Jodi I. Huggenvik, Ragbubir P. Sharma
Publikováno v:
Pharmacology & Toxicology. 76:17-22
Retinoic acid (RA) and its congeners mediate their biologic effects after binding to nuclear transcription factors called retinoic acid receptors. Biological effects and binding affinities to various receptors vary widely. Activation of transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d7a522a2309400cc9c6e3ed9d95577
https://doi.org/10.1111/j.1600-0773.1995.tb00096.x
https://doi.org/10.1111/j.1600-0773.1995.tb00096.x