Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jodi Dufner-Beattie"'
Autor:
Swati Mishra, James Dee, William Moar, Jodi Dufner-Beattie, James Baum, Naymã Pinto Dias, Andrei Alyokhin, Aaron Buzza, Silvia I. Rondon, Mark Clough, Sandy Menasha, Russell Groves, Justin Clements, Ken Ostlie, Gary Felton, Tim Waters, William E. Snyder, Juan Luis Jurat-Fuentes
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Insecticidal double-stranded RNAs (dsRNAs) silence expression of vital genes by activating the RNA interference (RNAi) mechanism in insect cells. Despite high commercial interest in insecticidal dsRNA, information on resistance to dsRNA is s
Externí odkaz:
https://doaj.org/article/e780da9e18344236be16c74090991e43
Autor:
Mark E. Clough, Silvia I. Rondon, Juan Luis Jurat-Fuentes, Naymã Pinto Dias, Sandy Menasha, Jodi Dufner-Beattie, Andrei Alyokhin, Timothy D. Waters, Russell L. Groves, William E. Snyder, Justin Clements, Kenneth R. Ostlie, William Moar, James Dee, Aaron M. Buzza, Gary W. Felton, James A. Baum, Swati Mishra
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Insecticidal double-stranded RNAs (dsRNAs) silence expression of vital genes by activating the RNA interference (RNAi) mechanism in insect cells. Despite high commercial interest in insecticidal dsRNA, information on resistance to dsRNA is scarce, pa
Publikováno v:
bchm. 388:1301-1312
Dietary zinc deficiency in mice is accompanied by enhanced expression of the zinc uptake transporter Slc39a4 (Zip4) and repressed expression of Slc39a5 (Zip5) in tissues which regulate zinc homeostasis (intestine, pancreas and visceral yolk sac). Her
Autor:
Jodi Dufner-Beattie, Jim Geiser, Jennifer L. Peters, David E. Salt, Wenhao Xu, Glen K. Andrews, Brett Lahner
Publikováno v:
genesis. 45:339-352
Fourteen members of the Slc39a superfamily of metal ion uptake transporters have been identified in mice and humans, but the physiological functions of most remain obscure. Herein, we created mice with Zip2 (Slc39a2) genes in which the open reading f
Publikováno v:
Journal of Biological Chemistry. 279:49082-49090
The ZIP5 gene encodes a protein closely related to ZIP4, a zinc transporter mutated in the human genetic disorder acrodermatitis enteropathica. Herein, we demonstrate that mouse ZIP5 and ZIP4 genes are co-expressed in several tissues involved in zinc
Autor:
Michael J. Petris, Fudi Wang, David J. Eide, Jodi Dufner-Beattie, Byung-Eun Kim, Glen K. Andrews
Publikováno v:
Journal of Biological Chemistry. 279:4523-4530
Zinc is an essential nutrient for all organisms. Its requirement in humans is illustrated dramatically by the genetic disorder acrodermatitis enteropathica (AE). AE is caused by the reduced uptake of dietary zinc by enterocytes, and the ensuing syste
Autor:
Michael J. Petris, Jodi Dufner-Beattie, David J. Eide, Byung-Eun Kim, Fudi Wang, Glen K. Andrews
Publikováno v:
Human Molecular Genetics. 13:563-571
The Zip4 protein is involved in dietary zinc uptake from the intestinal lumen. The human ZIP4 gene (SLC39A4) was identified because of its association with acrodermatitis enteropathica (AE), a genetic disorder of zinc absorption. To date, several SLC
Autor:
Yien-Ming Kuo, David J. Eide, Jodi Dufner-Beattie, Jane Gitschier, Fudi Wang, Glen K. Andrews
Publikováno v:
Journal of Biological Chemistry. 278:33474-33481
The human ZIP4 gene (SLC39A4) is a candidate for the genetic disorder of zinc metabolism acrodermatitis enteropathica. To understand its role in zinc homeostasis, we examined the function and expression of mouse ZIP4. This gene encodes a well conserv
Publikováno v:
The Journal of Nutrition. 133:45-50
Herein, the function of pancreatic metallothionein (MT)-I during zinc deficiency in pregnancy was examined using transgenic mice, which constitutively express the mouse MT-I gene driven by the rat elastase I promoter. Pancreatic MT protein levels and
Autor:
Mehmet Bilgen, Melissa C. Larson, Benjamin P. Weaver, Glen K. Andrews, Jodi Dufner-Beattie, Jim Geiser, Wenhao Xu
Publikováno v:
Human molecular genetics. 16(12)
The human Zip4 gene (Slc39a4) is mutated in the rare recessive genetic disorder of zinc metabolism acrodermatitis enteropathica, but the physiological functions of Zip4 are not well understood. Herein we demonstrate that homozygous Zip4-knockout mous