Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jodi L McBride"'
Autor:
Alison R. Weiss, William A. Liguore, Kristin Brandon, Xiaojie Wang, Zheng Liu, Christopher D. Kroenke, Jodi L. McBride
Publikováno v:
Current Research in Neurobiology, Vol 4, Iss , Pp 100090- (2023)
We recently generated a nonhuman primate (NHP) model of the neurodegenerative disorder Huntington's disease (HD) using adeno-associated viral vectors to express a fragment of mutant HTT protein (mHTT) throughout the cortico-basal ganglia circuit. Pre
Externí odkaz:
https://doaj.org/article/797dd838d6c74e3e85e84fbe193e9049
Autor:
Alison R Weiss, William A Liguore, Kristin Brandon, Xiaojie Wang, Zheng Liu, Jacqueline S Domire, Dana Button, Sathya Srinivasan, Christopher D Kroenke, Jodi L McBride
Publikováno v:
eLife, Vol 11 (2022)
We created a new nonhuman primate model of the genetic neurodegenerative disorder Huntington’s disease (HD) by injecting a mixture of recombinant adeno-associated viral vectors, serotypes AAV2 and AAV2.retro, each expressing a fragment of human mut
Externí odkaz:
https://doaj.org/article/40c54a4ae76146b79b16dfb2a213c0f2
Autor:
Brett D. Dufour, Jodi L. McBride
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 214-229 (2019)
Huntington's disease (HD) is a fatal genetic neurological disorder caused by a mutation in the human Huntingtin (HTT) gene. This mutation confers a toxic gain of function of the encoded mutant huntingtin (mHTT) protein, leading to widespread neuropat
Externí odkaz:
https://doaj.org/article/eb4e401d0d994ef5a54d5d54c298aad2
Autor:
Alison R. Weiss, Zheng Liu, Xiaojie Wang, William A. Liguore, Christopher D. Kroenke, Jodi L. McBride
Publikováno v:
NeuroImage, Vol 225, Iss , Pp 117517- (2021)
Macaques are the most common nonhuman primate (NHP) species used in neuroscience research. With the advancement of many neuroimaging techniques, new studies are beginning to apply multiple types of in vivo magnetic resonance imaging (MRI), such as st
Externí odkaz:
https://doaj.org/article/0e4e9b042e354c4ebae98f4412e60ff8
Autor:
Jodi L. McBride, Martha Neuringer, Betsy Ferguson, Steven G. Kohama, Ian J. Tagge, Robert C. Zweig, Laurie M. Renner, Trevor J. McGill, Jonathan Stoddard, Samuel Peterson, Weiping Su, Larry S. Sherman, Jacqueline S. Domire, Rebecca M. Ducore, Lois M. Colgin, Anne D. Lewis
Publikováno v:
Neurobiology of Disease, Vol 119, Iss , Pp 65-78 (2018)
We have identified a natural Japanese macaque model of the childhood neurodegenerative disorder neuronal ceroid lipofuscinosis, commonly known as Batten Disease, caused by a homozygous frameshift mutation in the CLN7 gene (CLN7−/−). Affected maca
Externí odkaz:
https://doaj.org/article/168900da9e314a49a97ffd11e624322e
Reduced D 2 / D 3 Receptor Binding and Glucose Metabolism in a Macaque Model of Huntington's Disease
Autor:
Alison R. Weiss, Daniele Bertoglio, William A. Liguore, Kristin Brandon, John Templon, Jeanne Link, Jodi L. McBride
Publikováno v:
Movement Disorders. 38:143-147
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1490071d8c44737b6f4bf22be363eca
https://doi.org/10.1002/mds.29271
https://doi.org/10.1002/mds.29271
Autor:
Nicholas S Caron, Arsalan S Haqqani, Akshdeep Sandhu, Amirah E Aly, Hailey Findlay Black, Jeffrey N Bone, Jodi L McBride, Abedelnasser Abulrob, Danica Stanimirovic, Blair R Leavitt, Michael R Hayden
Publikováno v:
Brain Communications. 4
The identification of molecular biomarkers in CSF from individuals affected by Huntington disease may help improve predictions of disease onset, better define disease progression and could facilitate the evaluation of potential therapies. The primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584587e3e69bee8be3eb098fc00707bd
https://doi.org/10.1093/braincomms/fcac309
https://doi.org/10.1093/braincomms/fcac309
Autor:
Nicholas S Caron, Arsalan S Haqqani, Akshdeep Sandhu, Amirah E Aly, Hailey Findlay Black, Jeffrey N Bone, Jodi L McBride, Abedelnasser Abulrob, Danica Stanimirovic, Blair R Leavitt, Michael R Hayden
Publikováno v:
D: Wet biomarkers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ac93dea464c3251027ccc73e5851d63
https://doi.org/10.1136/jnnp-2022-ehdn.72
https://doi.org/10.1136/jnnp-2022-ehdn.72
Autor:
Alison R Weiss, William A Liguore, Kristin Brandon, Xiaojie Wang, Zheng Liu, Jacqueline S Domire, Dana Button, Sathya Srinivasan, Christopher D Kroenke, Jodi L McBride
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::975ea988eccdf74536d1be51c9843198
https://doi.org/10.7554/elife.77568.sa2
https://doi.org/10.7554/elife.77568.sa2
Autor:
Alison R, Weiss, Daniele, Bertoglio, William A, Liguore, Kristin, Brandon, John, Templon, Jeanne, Link, Jodi L, McBride
Publikováno v:
Movement disorders : official journal of the Movement Disorder SocietyReferences.
Dopamine system dysfunction and altered glucose metabolism are implicated in Huntington's disease (HD), a neurological disease caused by mutant huntingtin (mHTT) expression.The aim was to characterize alterations in cerebral dopamine DPositron emissi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5dfcf01d7e0b05213a42a509118d1e7
https://pubmed.ncbi.nlm.nih.gov/36544385
https://pubmed.ncbi.nlm.nih.gov/36544385