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pro vyhledávání: '"Jocylin D, Pierro"'
Autor:
Jocylin D. Pierro, Bhavesh K. Ahir, Nancy C. Baker, Nicole C. Kleinstreuer, Menghang Xia, Thomas B. Knudsen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
All-trans retinoic acid (ATRA) gradients determine skeletal patterning morphogenesis and can be disrupted by diverse genetic or environmental factors during pregnancy, leading to fetal skeleton defects. Adverse Outcome Pathway (AOP) frameworks for AT
Externí odkaz:
https://doaj.org/article/fea4d4e314784441ac0b51c30c4f7898
Publikováno v:
Curr Opin Toxicol
New approach methodologies (NAMs) refer to any non-animal technology, methodology, approach, or combination thereof that can be used to provide information on chemical hazard and risk assessment that avoids the use of intact animals. A spectrum of in
Publikováno v:
ALTEX.
Evaluating chemicals for potential in vivo toxicity based on their in vitro bioactivity profile is an important step toward animal-free testing. A compendium of reference chemicals and data describing their bioactivity on specific molecular targets,